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作者:J. Olejnik , N. Suchowerska , M. Herrid ...
来源:[J].Animal Reproduction Science(IF 1.897), 2018, Vol.193, pp.58-67
摘要:... Further optimization of recipient irradiation protocols will add precision to the depletion of recipient spermatogonia prior to germ cell transplant. Three irradiation doses (9,12,15 Gy) were administered to ram lambs aged 14 weeks (Group 1) and 20 weeks (Group 2), then testi...
作者:Chunyan Zhao , Qinghua Liu , Shihong Xu ...
来源:[J].Theriogenology(IF 2.082), 2018, Vol.113, pp.137-145
摘要:... Recent research proved that type A spermatogonia possesses the properties of spermatogonia stem cell, and it might provide an ideal solution. Therefore, it is necessary to develop an appropriate molecular marker on type A spermatogonia to further isolate and purify of type A ...
作者:Yuki Niimi , Atsuki Imai , Hitomi Nishimura ...
来源:[J].Developmental Biology(IF 3.868), 2018
摘要:... However, it remains to be determined whether DND1 works with NANOS2 in the spermatogonia. Here, we show that DND1 is expressed in a subpopulation of differentiating spermatogonia and undifferentiated spermatogonia, including NANOS2-positive spermatogonia. Conditional disrupti...
作者:Jiajie Tu , Pengying Zhang , Alfred Chun Shui Luk ...
来源:[J].Experimental Cell Research(IF 3.557), 2018
摘要:Abstract(#br)During spermatogenesis, a group of undifferentiated spermatogonia undergoes an essential transition to a differentiating stage, which involves gain of Kit receptor. In the current study, we showed that a small non-coding RNA, miRNA-26b could induce transition from Ki...
作者:Won-Young Lee , Hyun-Jung Park , Ran Lee ...
来源:[J].Animal Reproduction Science(IF 1.897), 2017, Vol.185, pp.174-180
摘要:... Markers of male germ cells, including undifferentiated spermatogonia to fully developed spermatozoa have been identified in rodents, but not in dogs. In this study, to characterize the markers of undifferentiated spermatogonia, histological and immunohistochemical analys...
作者:Huan Cai , Jian-Ying Wu , Xing-Lan An ...
来源:[J].Animal Reproduction Science(IF 1.897), 2016, Vol.166, pp.109-115
摘要:... To explore the appropriate conditions for in vitro culture of bovine spermatogonia (containing putative SSCs), Sertoli cell monolayer and serum concentration were set as two main control factors. Morphological examination showed that the intactness and structure of adult bovi...
作者:Jeanette Olejnik , Natalka Suchowerska , Muren Herrid ...
来源:[J].Small Ruminant Research(IF 1.124), 2018, Vol.166, pp.22-27
摘要:... Spermatogonia numbers were not significantly reduced (27% change).(#br)The impact of irradiation doses (0–15 Gy) delivered with high precision to the testis by a 6 MV photon beam was assessed by serial biopsies. Sertoli cell numbers were depleted by 90% at 3 weeks in 15 Gy...
作者:Chencheng Yao , Qingqing Yuan , Minghui Niu ...
来源:[J].Molecular Therapy - Nucleic Acids, 2017, Vol.9, pp.182-194
摘要:Human spermatogenesis includes three main stages, namely, the mitosis of spermatogonia, meiosis of spermatocytes, and spermiogenesis of spermatids, which are precisely regulated by epigenetic and genetic factors. Abnormality of epigenetic and genetic factors can result in aberran...
作者:Meng-Qi Li , Ao-Lin Luo , Peng-Wei Zhao ...
来源:[J].Animal Reproduction Science(IF 1.897), 2017, Vol.186, pp.44-51
摘要:... However, little is known about Nanos2 in inchoate buffalo spermatogonia. Here, rapid-amplification of cDNA ends (RACE) was used to obtain the full-length buffalo Nanos2 sequence and bioinformatic analysis revealed a highly conserved Nanos2 sequence between buffalo and other m...
作者:Yuan Zhou , Jintao Yuan , Jiang Wu ...
来源:[J].Toxicology Letters(IF 3.145), 2012, Vol.212 (1), pp.48-56
摘要:... We examined whether MC-LR could enter spermatogonia and investigated the toxic effects of MC-LR on spermatogonia in vitro. Multispecific organic anion-transporting polypeptides (Oatps), which transported MCs, were screened as well. Spermatogonia were exposed to 0, 0.5, 5, 50,...

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