全部文献期刊会议图书|学者科研项目
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作者:Fang Li , Xin-Yu Xie , Xia-Fei Sui ...
来源:[J].Neuroscience(IF 3.122), 2020, Vol.432, pp.240-246
摘要:Abstract(#br)Protein and miRNA enrichment within extracellular vesicles (EVs) isolated from patients with Alzheimer’s disease (AD) has been shown to have putative diagnostic value. However, whether a combination of both will be more advantageous is unknown. EVs were enriched...
作者:Kryspin Andrzejewski , Katarzyna Kaczyńska , Małgorzata Zaremba
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)
摘要:Malfunctioning of the serotonergic system in Parkinson’s disease may contribute to non-motor symptoms such as respiratory complications. Thus the aim of our study was to investigate the role of serotonin 5-HT2 receptors in the modulation of normoxic breathing and...
作者:Daria V. Rakitina , Alexander I. Manolov , Alexandra V. Kanygina ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)
摘要:... coli ) has been increasingly implicated in the pathogenesis of Crohn’s disease (CD). The phylogeny of E. coli isolated from Crohn’s disease patients (CDEC) was controversial, and while genotyping results suggested heterogeneity, the sequenced strains of E. coli from CD...
作者:Molood Alsadat Vakilinezhad , Azadeh Amini , Hamid Akbari Javar ...
来源:[J].DARU Journal of Pharmaceutical Sciences, 2018, Vol.26 (2), pp.165-177
摘要:Abstract(#br) Background(#br)Nicotinamide is considered to be effective in halting the Alzheimer’s disease progression. The body could absorb a limited amount of nicotinamide at a time, requiring multiple doses through a day. To overcome such an obstacle which reduces the pat...
作者:Minghua Wu , Min Li , Jun Yuan ...
来源:[J].Pharmacological Research(IF 4.346), 2020
摘要:Abstract(#br)Hormone therapy continues to be a favourable option in the management of menopausal symptomatology, but the associated risk-benefit ratios with respect to neurodegenerative diseases remain controversial. The study aim was to determine the relation between menopausal...
作者:Rejko Krüger , Paul Lingor , Triantafyllos Doskas ...
来源:[J].Advances in Therapy(IF 2.125), 2017, Vol.34 (7), pp.1741-1752
摘要:Continuous delivery of levodopa–carbidopa intestinal gel (LCIG) by percutaneous endoscopic gastrojejunostomy (PEG-J) in advanced Parkinson’s disease (PD) patients reduces variability in plasma levels, providing better control of motor fluctuations (“on” and “off”...
作者:Shih-Ya Hung , Wen-Mei Fu
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)
摘要:Alzheimer’s disease (AD) is a major form of senile dementia, characterized by progressive memory and neuronal loss combined with cognitive impairment. AD is the most common neurodegenerative disease worldwide, affecting one-fifth of those aged over 85 years. Recent therape...
作者:Vivek Tiwari , Kamal Saba , Pandichelvam Veeraiah ...
来源:[J].Journal of Biosciences(IF 1.759), 2017, Vol.42 (3), pp.363-371
摘要:Alzheimer’s disease (AD) is the most common neurodegenerative disorder characterized by progressive loss of memory and cognitive function. The cerebral metabolic rate of glucose oxidation has been shown to be reduced in AD. The present study evaluated efficacy of dietary Am...
作者:Rongfeng Liu , Yu-Chih Liu , Junwei Meng ...
来源:[J].Analytical and Bioanalytical Chemistry(IF 3.659), 2017, Vol.409 (28), pp.6635-6642
摘要:The β-secretase (BACE1) initiates the generation of toxic amyloid-β peptide (Aβ) from amyloid-β precursor protein (APP), which was widely considered to play a key role in the pathogenesis of Alzheimer’s disease (AD). Here, a novel microfluidics-based mobility shift assa...

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