全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Terruzzi Ileana , Montesano Anna , Senesi Pamela ...
来源:[J].Endocrine(IF 2.25), 2017, Vol.58 (1), pp.33-45
摘要:The purpose of this study is to investigate Ranolazine action on skeletal muscle differentiation and mitochondrial oxidative phenomena. Ranolazine, an antianginal drug, which acts blocking the late INaL current, was shown to lower hemoglobin A1c in patients with diabetes. In the ...
作者:Elaine Nguyen , Craig I. Coleman , Christine G. Kohn ...
来源:[J].International Journal of Cardiology(IF 5.509), 2018
摘要:... Ranolazine has been shown to reduce angina frequency versus placebo in patients with T2D and stable angina. We sought to estimate the cost-effectiveness of ranolazine when added to standard-of-care (SoC) versus SoC alone in patients with T2D and stable, but symptomatic c...
作者:Adam P. Bress , John A. Dodson , Jordan B. King ...
来源:[J].The American Journal of Cardiology(IF 3.209), 2018
摘要:ABSTRACT(#br)Real-world outcomes among patients with chronic stable angina treated with ranolazine and other antianginal medications as second- or third-line therapy are limited. In a historical cohort study of veterans with chronic stable angina, we compared time to coronary r...
作者:Vedant S. Pargaonkar , Jennifer A. Tremmel , Ingela Schnittger ...
来源:[J].International Journal of Cardiology(IF 5.509), 2020
摘要:... We studied the effect of ranolazine on symptoms and quality of life (QOL) in these patients.(#br)Methods(#br)We retrospectively studied 53 patients prescribed with ranolazine, matched on sex and age, with 106 patients on standard of care who underwent comprehensive invasive...
作者:Wojciech Zareba , James P. Daubert , Christopher A. Beck ...
来源:[J].Journal of the American College of Cardiology(IF 14.086), 2018, Vol.72 (6), pp.636-645
摘要:...(#br)Objectives(#br)This study aimed to determine whether ranolazine administration decreases the likelihood of VT, VF, or death in patients with an ICD.(#br)Methods(#br)This was double-blind, placebo-controlled clinical trial in which high-risk ICD patients with ischemic ...
作者:Kinjal Banerjee , Raktim Kumar Ghosh , Sravani Kamatam ...
来源:[J].International Journal of Cardiology(IF 5.509), 2017, Vol.227, pp.556-564
摘要:Abstract(#br)Ranolazine was FDA approved for chronic angina in 2006. Since then, there has been extensive research involving this drug. The mechanism of action, debatable at the time of approval, has been demonstrated. Ranolazine acts via inhibition of late sodium channel current...
作者:Benedetta Terragni , Paolo Scalmani , Elisa Colombo ...
来源:[J].Neuropharmacology(IF 4.114), 2016, Vol.110, pp.223-236
摘要:... Ranolazine, a Na V -blocker approved for treatment of angina pectoris, is considered a preferential inhibitor of I NaP and has been proposed as a novel AED. Although it is thought that classic Na V -blockers used as AEDs target mainly I NaT , they can also reduce I NaP . It ...
作者:Panagiotis Efentakis , Ioanna Andreadou , Sophia-Iris Bibli ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2016, Vol.789, pp.431-438
摘要:Abstract(#br)We tested the hypothesis that ranolazine (Ran) is cardioprotective in a model of ischemia /reperfusion and we elucidated the intracellular mechanism. Anesthetized rabbits were subjected to is chemia and reperfusion and were divided into 5 groups: 1) Control, 2) Pre...
作者:Houyong Zhu , Xiaoqun Xu , Xiaojiang Fang ...
来源:[J].Clinical Therapeutics(IF 2.23), 2019, Vol.41 (10), pp.2137-2152.e12
摘要:Abstract(#br)Purpose(#br)The goal of this study was to investigate the effects of the antianginal drugs ranolazine, nicorandil, and ivabradine on coronary microvascular function.(#br)Methods(#br)Electronic scientific databases were searched for randomized trials investigating th...
作者:Hidehira Fukaya , Bradley N. Plummer , Joseph S. Piktel ...
来源:[J].Heart Rhythm(IF 5.045), 2018
摘要:...(#br)OBJECTIVE(#br)We determined if ranolazine suppresses cardiac alternans in HF by normalizing Ca 2+ cycling.(#br)METHODS(#br)Transmural dual optical mapping of Ca 2+ transients and action potentials was performed in wedge preparations from 8 HF and 8 control (Normal) dogs....

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×