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作者:Robert L. Baker , Yulia Yarkhunova , Katherine Vidal ...
来源:[J].BMC Plant Biology(IF 4.354), 2017, Vol.17 (1)
摘要:Polyploidy is well studied from a genetic and genomic perspective, but the morphological, anatomical, and physiological consequences of polyploidy remain relatively uncharacterized. Whether these potential changes bear on functional integration or are idiosyncratic remains an ope...
作者:Stefanie M. Ickert-Bond , Aretuza Sousa , Ya Min ...
来源:[J].Molecular Phylogenetics and Evolution(IF 4.066), 2020, Vol.147
摘要:Abstract(#br)While polyploidization is recognized as a major evolutionary driver for ferns and angiosperms, little is known about its impact in gymnosperms, where polyploidy is much less frequent. We explore Ephedra to evaluate (i) the extent of genome size diversity in the gen...
作者:Yanxiu Mo , Yunpeng Fan , Wen Fu ...
来源:[J].Fish and Shellfish Immunology(IF 2.964), 2019, Vol.84, pp.656-663
摘要:Abstract(#br)Previous research has indicated that the small compound, SP600125, could induce polyploidy of fish cells, and has established a stable tetraploid cell line from diploid fish cells. In order to explore how fish cells maintain homeostasis under SP600125-stress in vit...
作者:Evan K. Pacey , Hafiz Maherali , Brian C. Husband
来源:[J].Ecology and Evolution(IF 1.184), 2020, Vol.10 (1), pp.198-216
摘要:Abstract(#br)Whole genome duplication, leading to polyploidy and endopolyploidy, occurs in all domains and kingdoms and is especially prevalent in vascular plants. Both polyploidy and endopolyploidy increase cell size, but it is unclear whether both processes have similar effect...
作者:Sanjeev Gupta
来源:[J].Seminars in Cancer Biology(IF 7.436), 2000, Vol.10 (3), pp.161-171
摘要:Abstract(#br)The onset of cellular polyploidy is recognized in all differentiated mammalian tissues. Polyploidy has been noted frequently in the normal liver, as well as in pathophysiological states of the liver. As insights into the significance of polyploidy accumulate graduall...
作者:Johanna Sigl-Glöckner , Michael Brecht
来源:[J].Cell Reports, 2017, Vol.20 (11), pp.2575-2583
摘要:Summary(#br)In many species, polyploidy, in which an increase in nuclear DNA content is accompanied by an increase in cell size, contributes to cellular diversity. In the rat visual cortex, most neurons are small and homogeneous in size, while layer 5 cells are heterogeneous, co...
作者:Zhang , Lin , Tarlow ...
来源:[J].Cell Cycle(IF 5.243), 2019, Vol.18 (12), pp.1302-1315
摘要:... The original observations of liver polyploidy date back to the 1940s, but functional roles for polyploid cells are still unclear. Liver polyploidy may influence regeneration, stress response, and cancer, although little evidence has established direct causal links between polyploidy...
作者:Chaonan Shi , Lei Zhao , Xiangfen Zhang ...
来源:[J].BMC Plant Biology(IF 4.354), 2019, Vol.19 (1), pp.6
摘要:Abstract Background The extensive adaptability of polyploidy wheat is attributed to its complex genome, and accurately controlling heading stage is a prime target in wheat breeding process. Wheat heading stage is an essential growth and development processes since it starts at a ...
作者:Yi Tan , Meiling Li , Sandra Cox ...
来源:[J].Developmental Biology(IF 3.868), 2003, Vol.265 (1), pp.181-195
摘要:Abstract(#br)Stromal cell polyploidy is a unique phenomenon that occurs during uterine decidualization following embryo implantation, although the developmental mechanism still remains elusive. The general consensus is that the aberrant expression and altered functional activity ...
作者:Sharad Sharma , Hang-Ping Yao , Yong-Qing Zhou ...
来源:[J].Molecular Oncology(IF 6.701), 2014, Vol.8 (3), pp.469-482
摘要:... We have previously shown that BMS-777607 induces chemoresistance in vitro by causing polyploidy, which hampers therapeutic efficacy. Here, we studied polyploidy-associated senescence induced by BMS-777607 in breast cancer cells and its prevention by mTOR inhibitor AZD8055, l...

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