全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Kazuhide Takada , Shihoko Komine-Aizawa , Naoko Hirohata ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)Springer
摘要:... The systemic administration of polyriboinosinic-polyribocytidylic acid (poly I:C ; a substitute for viral dsRNA and a ligand of toll-like receptor 3), enhances wound healing in vivo. The aim of this study is to improve our understanding of the link between innate immunity and...
作者:Shaopin Zhu , Xun Xu , Lili Wang ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2017, Vol.15 (1)Springer
摘要:Keratitis is a common cause of blindness. Current anti-inflammatory drugs used in keratitis have profound side effects. Small peptides derived from endogenous proteins potentially display both desired efficiency and safety. We identified an 11-amino-acid peptide, H-RN, from hepat...
作者:Anita Müller , Ben J. G. Sutherland , Ben F. Koop ...
来源:[J].BMC Genomics(IF 4.397), 2015, Vol.16 (1)Springer
摘要:... Moreover, following challenge with poly(I:C), survivors and carriers displayed an elevated antiviral immune response in comparison to naïve fish.(#br) Conclusions(#br)IHN virus persistence was identified in Sockeye Salmon where it elicited a unique brain transcriptome profi...
作者:Lawrence Mok , James W. Wynne , Kris Ford ...
来源:[J].Proteome Science(IF 2.42), 2015, Vol.13 (1)Springer
摘要:... Here, we investigated the differential protein expression of immortalised Pteropus alecto kidney cells (PaKiT03) following transfection with the viral mimic, Poly I:C. Two complementary proteomic approaches, difference gel electrophoresis (DIGE) and isobaric tagging for relat...
作者:Jiying Wang , Yanping Wang , Huaizhong Wang ...
来源:[J].G3: Genes, Genomes, Genetics(IF 1.794), 2016, Vol.6 (5), pp.1267-1275DOAJ
摘要:Polyinosinic-polycytidylic acid (poly I:C), a synthetic dsRNA analog, has been demonstrated to have stimulatory effects similar to viral dsRNA. To gain deep knowledge of the host transcriptional response of pigs to poly I:C stimulation, in the present study, we cultured and stimu...
作者:Villena Julio , Chiba Eriko , Tomosada Yohsuke ...
来源:[J].BMC Immunology(IF 2.61), 2012, Vol.13 (1)DOAJ
摘要:... To mimic the pro-inflammatory and physiopathological consecuences of RNA viral infections in the lung, we used an experimental model of lung inflammation based on the administration of the artificial viral pathogen-associated molecular pattern poly(I:C). Nasal administrati...
作者:Khalil Eslamloo , Xi Xue , Jennifer R. Hall ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:... These diets were designed to be relatively low in EPA + DHA (i.e. FO7: 1.41% and FO5: 1%), but near the requirement level, and resulting in comparable growth. Vegetable oil (i.e. rapeseed oil) was used to balance fish oil in experimental diets. After a 16-week feeding trial, ...
作者:Yohannes A. Mebratu , Kevin R. Smith , Getahun E. Agga ...
来源:[J].Respiratory Research(IF 3.642), 2016, Vol.17 (1)Springer
摘要:... However, the extent of inflammatory responses and lung pathologies of mice exposed to CS and infected with influenza A virus (IAV), respiratory syncytial virus (RSV), or treated with the viral derivative dsRNA (polyinosine-polycytidylic acid [poly (I:C)] have not been com...
作者:Flavia S. Mueller , Juliet Richetto , Lindsay N. Hayes ...
来源:[J].Brain Behavior and Immunity(IF 5.612), 2019, Vol.80, pp.406-418Elsevier
摘要:Abstract(#br)Maternal immune activation (MIA) models that are based on administration of the viral mimetic, poly(I:C), are widely used as experimental tools to study neuronal and behavioral dysfunctions in relation to immune-mediated neurodevelopmental disorders and mental ill...
作者:H.M. Kowash , H.G. Potter , M.E. Edye ...
来源:[J].Brain Behavior and Immunity(IF 5.612), 2019Elsevier
摘要:Abstract(#br)The viral mimetic polyinosinic:polycytidylic acid (poly(I:C)) is increasingly used to induce maternal immune activation (mIA) to model neurodevelopmental disorders (NDDs). Robust and reproducible phenotypes across studies are essential for the generation of models th...

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