全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Trung N. Le , Brian W. Blakley
来源:[J].Journal of Otolaryngology - Head & Neck Surgery(IF 0.715), 2017, Vol.46 (1)Springer
摘要:... In this report, we demonstrated a unique method of controlling the BLB, and established the pharmacokinetics of gentamicin in perilymph, cerebrospinal fluid (CSF) and blood with and without mannitol.
作者:Hsiao-Chun Lin , Yin Ren , Andrew C Lysaght ...
来源:[J].PLoS ONE(IF 3.73), 2019, Vol.14 (6)DOAJ
摘要:... Perilymph sampling can thus provide molecular cues to hearing and balance disorders. While such "liquid biopsy" of the inner ear is not yet in routine clinical practice, previous studies have uncovered alterations in perilymph in patients with certain types of hearing loss. H...
作者:Kristian Pirttilä , Pernilla Videhult Pierre , Jakob Haglöf ...
来源:[J].Metabolomics(IF 4.433), 2019, Vol.15 (10), pp.1-12Springer
摘要:...(#br) Objectives(#br)To present a protocol for untargeted metabolomics of guinea pig perilymph and investigate the effect of H 2 administration on the perilymph metabolome of noise exposed guinea pigs.(#br) Methods(#br)The left ear of guinea pigs were exposed to hazardous im...
作者:A. N. Salt , R. M. Gill , J. J. Hartsock
来源:[J].Journal of the Association for Research in Otolaryngology(IF 2.952), 2015, Vol.16 (3), pp.357-371Springer
摘要:Abstract(#br)Understanding how drugs are distributed in perilymph following local applications is important as local drug therapies are increasingly used to treat disorders of the inner ear. The potential contribution of cerebrospinal fluid (CSF) entry to perilymph homeostas...
作者:Tetsuo Ikezono , Tomohiro Matsumura , Han Matsuda ...
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.13 (1)DOAJ
摘要:Perilymphatic fistula is defined as an abnormal communication between the perilymph-filled space and the middle ear, or cranial spaces. The manifestations include a broad spectrum of neuro-otological symptoms such as hearing loss, vertigo/dizziness, disequilibrium, aural fullne...
作者:Mian Zu , Jinan Jiang , Hui Zhao ...
来源:[J].Journal of Chromatography B(IF 2.487), 2018Elsevier
摘要:... The aim of this work was to develop and validate an analytical method suitable for the detection and quantification of neomycin in cochlear perilymph of guinea pig after local application. The SupelMIP SPE column was used for the pre-treatment of matrix. Chromatographic sep...
作者:Alec N. Salt , Jared J. Hartsock , Ruth M. Gill ...
来源:[J].Journal of the Association for Research in Otolaryngology(IF 2.952), 2012, Vol.13 (6), pp.771-783Springer
摘要:Abstract(#br)Perilymph pharmacokinetics was investigated by a novel approach, in which solutions containing drug or marker were injected from a pipette sealed into the perilymphatic space of the lateral semi-circular canal (LSCC). The cochlear aqueduct provides the outlet for flu...
作者:Varun V. Varadarajan , Orrin L. Dayton , Reordan O. De Jesus ...
来源:[J].International Journal of Pediatric Otorhinolaryngology(IF 1.35), 2019, Vol.126Elsevier
摘要:Abstract(#br)Objectives(#br)Perilymph gusher (PLG), an uncommon complication of otologic surgery, has been attributed to communication between the cochlea and the internal auditory canal (IAC). Subtle osseous defects may be missed on routine review of computed tomography (CT)....
作者:Varun V. Varadarajan , Orrin L. Dayton , Reordan O. De Jesus ...
来源:[J].International Journal of Pediatric Otorhinolaryngology(IF 1.35), 2019, Vol.126Elsevier
摘要:Abstract(#br)Objectives(#br)Perilymph gusher (PLG), an uncommon complication of otologic surgery, has been attributed to communication between the cochlea and the internal auditory canal (IAC). Subtle osseous defects may be missed on routine review of computed tomography (CT)....
作者:Robert Mynatt , Shane A. Hale , Ruth M. Gill ...
来源:[J].Journal of the Association for Research in Otolaryngology(IF 2.952), 2006, Vol.7 (2), pp.182-193Springer
摘要:... Measurement of drug levels in ST is technically difficult because of the known contamination of perilymph samples taken from the basal cochlear turn with cerebrospinal fluid (CSF). Recently, we reported a technique in which perilymph was sampled from the cochlear apex to m...

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