全部文献期刊会议图书|学者科研项目
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作者:Thao-Quyen Nguyen-Pham , Lazhar Benyahia , Guillaume Bastiat ...
来源:[J].Journal of Colloid And Interface Science(IF 3.172), 2020, Vol.561, pp.838-848
摘要:... The aim of this study was to identify the key parameters influencing the behavior of PLGA polymer-based droplets falling into a complex extraction medium, to select appropriate conditions for prilling.(#br)Experiments(#br)Polymer solutions and extraction media were characteri...
作者:Sergio Alberto Bernal-Chávez , Sergio Alcalá-Alcalá , Doris Cerecedo ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2020, Vol.146
摘要:Abstract(#br)A thermo-responsive hydrogel of Pluronic F-127, containing PLGA nanoparticles loaded with a platelet lysate for wound treatment, was prepared. A high rate of incorporation of the lysate (about 80%) in the nanoparticles was achieved by the double emulsion-solvent evap...
作者:Tugba Eren Boncu , Aylin Uskudar Guclu , Mehmet Faruk Catma ...
来源:[J].International Journal of Pharmaceutics(IF 3.458), 2020, Vol.573
摘要:Abstract(#br)In this study, it was aimed to formulate linezolid loaded electrospun PLGA and PCL fiber mats doing controlled drug release, to be used in the treatment and prophylaxis of the prosthesis related infections. The effect of PLGA concentration, PLGA to PCL ratio and th...
作者:Wei Fan , Yanyun Li , Qing Sun ...
来源:[J].Materials Science & Engineering C(IF 2.404), 2020
摘要:... In the present study, poly(D,L-lactic- co -glycolide) (PLGA) submicron particles were used as carriers to deliver an antimicrobial quaternary ammonium silane (code-named K21) as well as calcium and phosphorus elements. The release profiles, antibacterial ability against E. fa...
作者:Frantiescoli Anversa Dimer , Cristiane de Souza Carvalho-Wodarz , Adriely Goes ...
来源:[J].Nanomedicine: Nanotechnology, Biology, and Medicine(IF 6.93), 2020, Vol.24
摘要:... To reach intracellular Staphylococcus aureus and Mycobacterium abscessus, we encapsulated clarithromycin in PLGA nanocapsules, suitable for aerosol delivery by nebulization of an aqueous dispersion. Compared to the same dose of free clarithromycin, nanoencapsulation reduc...
作者:M.A. Sevostyanov , A.S. Baikin , K.V. Sergienko ...
来源:[J].Reactive and Functional Polymers(IF 2.505), 2020, Vol.150
摘要:Abstract(#br)The work describes synthesis of novel biodegradable polymer membranes based on poly(lactic- co -glycolic acid) (PLGA), as well as testing of their physicochemical properties. The membranes synthesized have been shown to possess the necessary mechanical properties an...
作者:Kinam Park , Sarah Skidmore , Justin Hadar ...
来源:[J].Journal of Controlled Release(IF 7.633), 2019, Vol.304, pp.125-134
摘要:Abstract(#br)Injectable, long-acting depot formulations based on poly(lactide- co -glycolide) (PLGA) have been used clinically since 1989. Despite 30 years of development, however, there are only 19 different drugs in PLGA formulations approved by the U.S. Food and Drug Administr...
作者:Enqi Zhang , Vasilisa Zhukova , Aleksey Semyonkin ...
来源:[J].European Journal of Pharmaceutics and Biopharmaceutics(IF 3.826), 2020
摘要:Abstract(#br)PLGA (poly(lactic-co-glycolic acid))-based nanoparticles (NPs) are promising carrier-cargo systems because of their excellent biocompatibility and possibility of sustained drug release. However, it is not well understood how the kinetics of such drug delivery system ...
作者:Bernhard Brauner , Patrik Schwarz , Michael Wirth ...
来源:[J].International Journal of Pharmaceutics(IF 3.458), 2020, Vol.579
摘要:...3] of 1–9 µm) and nanoparticles (Z-Avg of 200–400 nm) were prepared from two types of poly( d , l -lactic -co- glycolic acid) (PLGA) for instillative therapy. While PLGA 503H microparticles could not be loaded with more than 2.6% trimethoprim, PLGA 2300 entrapped 22%....
作者:G. Dollo , Y. Boucaud , M. Amela-Cortes ...
来源:[J].International Journal of Pharmaceutics(IF 3.458), 2020, Vol.576
摘要:Abstract(#br)We present a screening of poly (D,L-lactide-co-glycolide) (PLGA) nanoparticles embedding a series of inorganic molybdenum octahedral clusters intended for photodynamic therapy (PDT) of cancer. Three cluster compounds from 2 cluster units, [{Mo 6 Br 8 }Br 6 ] 2− a...

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