全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Wissam Beaino , Bieneke Janssen , Gijs Kooij ...
来源:[J].Journal of Neuroinflammation(IF 4.351), 2017, Vol.14 (1)Springer
摘要:... Positron emission tomography (PET) imaging is a powerful non-invasive technique that allows real-time imaging of microglia activation phenotypes in the central nervous system, depending on the availability of selective PET tracers. Our objective is to investigate and characte...
作者:Laure Saint-Aubert , Laetitia Lemoine , Konstantinos Chiotis ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2017, Vol.12 (1)Springer
摘要:... The advances of molecular imaging in the recent years have now led to the recent development of promising tau-specific tracers for positron emission tomography (PET), such as THK5317, THK5351, AV-1451, and PBB3. These tracers are now available for clinical assessment in pat...
作者:Daniele Paula Faria , Sjef Copray , Carlos Buchpiguel ...
来源:[J].Journal of Neuroimmune Pharmacology(IF 3.802), 2014, Vol.9 (4), pp.468-482Springer
摘要:Abstract(#br)Positron emission tomography (PET) is a non-invasive technique for quantitative imaging of biochemical and physiological processes in animals and humans. PET uses probes labeled with a radioactive isotope, called PET tracers, which can bind to or be converted by a sp...
作者:Ali Ahmadi , Stephanie L. Thorn , Emilio I. Alarcon ...
来源:[J].Biomaterials(IF 7.604), 2015, Vol.49, pp.18-26Elsevier
摘要:... Matrix imaging would be useful for evaluating these important properties. Herein, hexadecyl-4-[ 18 F]fluorobenzoate ( 18 F-HFB) and Qdot labeling was used to evaluate collagen matrix delivery in a mouse model of myocardial infarction (MI). At 1wk post-MI, mice received myoc...
作者:Guiqing Liu , Wei Wang , Jianguo Lin ...
来源:[J].Journal of Radioanalytical and Nuclear Chemistry(IF 1.467), 2017, Vol.312 (3), pp.599-607Springer
摘要:16α-18F-fluoroestradiol (18F-FES) has been developed as a promising positron emission tomography (PET) imaging agent for targeting estrogen receptor positive (ER+) breast cancer in the clinical trial. However, the radiosynthesis of 18...
作者:Christian Uprimny , Alexander Stephan Kroiss , Josef Fritz ...
来源:[J].European Journal of Nuclear Medicine and Molecular Imaging(IF 5.114), 2017, Vol.44 (10), pp.1647-1655Springer
摘要:PET/CT using 68Ga-labelled prostate-specific membrane antigen PSMA-11 (HBEDD-CC) has emerged as a promising imaging method in the diagnostic evaluation of prostate cancer (PC) patients with biochemical recurrence. However, assessment of local recurrence (LR) may be lim...
作者:Yangchun Xin , Hancheng Cai
来源:[J].Molecular Imaging and Biology(IF 3.095), 2017, Vol.19 (4), pp.589-598Springer
摘要:... Imaging IDO-mediated kynurenine pathway of tryptophan metabolism with positron emission tomography (PET) could provide valuable information for noninvasive assessment of cancer immunotherapy response. In this work, radiotracer 1-(2-[18F]fluoroethyl)-L-tryptophan (1...
作者:Christian Brand , Valerie A. Longo , Mike Groaning ...
来源:[J].Molecular Imaging and Biology(IF 3.095), 2017, Vol.19 (5), pp.754-761Springer
摘要:... It was therefore the aim of this study to develop a folate-derived Ga-68-based positron emission tomography (PET) imaging tracer that is straightforward to radiolabel and could be broadly used in clinical studies. We validated its target binding affinity and specificity and c...
作者:Nisha Singh , Mattia Veronese , Jim O'Doherty ...
来源:[J].Nuclear Medicine and Biology(IF 2.517), 2018Elsevier
摘要:Abstract(#br)Introduction(#br)The development of clinically useful tracers for PET imaging is enormously challenging and expensive. The intranasal (IN) route of administration is purported to be a viable route for delivering drugs to the brain but has, as yet, not been investigat...
作者:Sang Ju Lee , Seung Jun Oh , Eun Hye Cho ...
来源:[J].Journal of Radioanalytical and Nuclear Chemistry(IF 1.467), 2017, Vol.314 (3), pp.1587-1593Springer
摘要:[18F]THK-5351, a new candidate for tau protein imaging, is based on an aryl quinoline structure. We report the full automatic synthesis using disposable cassettes under pH controlled [18F]fluorination. After the trapping of 88.5 ± 21.9 GBq of [18...

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