全部文献期刊会议图书|学者科研项目
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作者:Rumena Petkova , Pavlina Chelenkova , Husein Yemendzhiev ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2013, Vol.27 (6), pp.4217-4221
摘要:... The P72R polymorphism in the human TP53 gene has been contemplated as an independent phenotype modifier in cancers, especially the R allele which has been shown to confer higher pro-apoptotic properties to the resultant p53 protein. It has been demonstrated, however, that RR ...
作者:S. Ozlem Altinkaya , Sumeyra N. Avcioglu , Selda D. Sezer ...
来源:[J].Journal of Obstetrics and Gynaecology Research(IF 0.841), 2019, Vol.45 (10), pp.2088-2094
摘要:... The results indicated that P72R/P72R genotype increased the risk of leiomyoma development by 6.3 fold (95% confidence interval [CI]: 2.880–13.793). There was a negative correlation between P72R/WT genotype and leiomyoma development (OR = 0.261, 95% CI: 0.114–0.596). P72R/...
作者:Rumena Petkova , Pavlina Chelenkova , Husein Yemendzhiev ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2013, Vol.27 (6), pp.4217-4221
摘要:... The P72R polymorphism in the human TP53 gene has been contemplated as an independent phenotype modifier in cancers, especially the R allele which has been shown to confer higher pro-apoptotic properties to the resultant p53 protein. It has been demonstrated, however, that RR ...
作者:Che-Pei Kung , Julia I-Ju Leu , Subhasree Basu ...
来源:[J].Cell Reports, 2016, Vol.14 (10), pp.2413-2425
摘要:Summary(#br)p53 is well known for its tumor suppressor role, but this protein also has a poorly understood role in the regulation of metabolism. Human studies have implicated a common polymorphism at codon 72 of p53 in diabetic and pre-diabetic phenotypes. To understand this role...
作者:Che-Pei Kung , Julia I-Ju Leu , Subhasree Basu ...
来源:[J].Cell Reports, 2016, Vol.14 (10), pp.2413-2425
摘要:p53 is well known for its tumor suppressor role, but this protein also has a poorly understood role in the regulation of metabolism. Human studies have implicated a common polymorphism at codon 72 of p53 in diabetic and pre-diabetic phenotypes. To understand this role, we utilize...
作者:Szymon Zmorzyński , Magdalena Wojcierowska-Litwin , Małgorzata Kowal ...
来源:[J].BioMed Research International, 2020, Vol.2020
摘要:Introduction . NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies ...
作者:Panni Simona , Salvioli Stefano , Santonico Elena ...
来源:[J].Journal of biochemistry, 2015, Vol.157 (2), pp.101-11
摘要:... SH3 and WW), and we present the first demonstration that the purified SH3 domains of the CD2AP/Cin85 protein family are able to directly bind the p53 protein, and to discriminate between the two polymorphic variants P72R.
作者:Altinkaya S Ozlem , Avcioglu Sumeyra N , Sezer Selda D ...
来源:[J].The journal of obstetrics and gynaecology research, 2019, Vol.45 (10), pp.2088-2094
摘要:... The results indicated that P72R/P72R genotype increased the risk of leiomyoma development by 6.3 fold (95% confidence interval [CI]: 2.880-13.793). There was a negative correlation between P72R/WT genotype and leiomyoma development (OR = 0.261, 95% CI: 0.114-0.596). P72R/P72R...

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