全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Rubén Aquino-Martínez , Alcira P. Angelo , Francesc Ventura Pujol
来源:[J].Stem Cell Research & Therapy(IF 3.652), 2017, Vol.8 (1)Springer
摘要:Osteoinduction and subsequent bone formation rely on efficient mesenchymal stem cell (MSC) recruitment. It is also known that migration is induced by gradients of growth factors and cytokines. Degradation of Ca2+-containing biomaterials mimics the bone remodeling compa...
作者:J. Eyckmans , S. J. Roberts , J. Schrooten ...
来源:[J].Journal of Cellular and Molecular Medicine(IF 4.753), 2010, Vol.14 (6b), pp.1845-1856Wiley
摘要:... In addition, inhibition of endogenous bone morphogenetic protein and Wnt signalling by overexpression of the secreted antagonists Noggin and Frzb, respectively, also abrogated osteoinduction. Proliferation of the engrafted HPDCs was strongly reduced in the decalcified scaffo...
作者:Arlyng González-Vázquez , Josep A. Planell , Elisabeth Engel
来源:[J].Acta Biomaterialia(IF 5.093), 2014, Vol.10 (6), pp.2824-2833Elsevier
摘要:... The objective of the present work is to evaluate the roles of extracellular calcium ([Ca 2+ ] o ) and the CaSR in osteoinduction. Rat bone marrow mesenchymal stromal cells (rBMSCs) were stimulated with 10 mM of Ca 2+ . Several experiments were conducted to demonstrate the ...
作者:A. Fukuda , M. Takemoto , T. Saito ...
来源:[J].Acta Biomaterialia(IF 5.093), 2011, Vol.7 (5), pp.2327-2336Elsevier
摘要:Abstract(#br)Many studies have shown that certain biomaterials with specific porous structures can induce bone formation in non-osseous sites without the need for osteoinductive biomolecules, however, the mechanisms responsible for this phenomenon (intrinsic osteoinduction of b...
作者:Yoshitake Takahashi , Masaya Yamamoto , Yasuhiko Tabata
来源:[J].Biomaterials(IF 7.604), 2005, Vol.26 (23), pp.4856-4865Elsevier
摘要:... The in vivo osteoinduction activity of the sponges incorporating BMP-2 was investigated, while their in vivo profile of BMP-2 release was evaluated. The sponges prepared had an interconnected pore structure with an average pore size of 200 μm, irrespective of the β -TCP ...
作者:Noel L. Davison , Anne-Laure Gamblin , Pierre Layrolle ...
来源:[J].Biomaterials(IF 7.604), 2014, Vol.35 (19), pp.5088-5097Elsevier
摘要:Abstract(#br)Bone graft substitutes such as calcium phosphates are subject to the innate inflammatory reaction, which may bear important consequences for bone regeneration. We speculate that the surface architecture of osteoinductive β-tricalcium phosphate (TCP) stimulates t...
作者:Lijia Cheng , Feng Ye , Ruina Yang ...
来源:[J].Acta Biomaterialia(IF 5.093), 2009, Vol.6 (4), pp.1569-1574Elsevier
摘要:Abstract(#br)Many studies have shown that calcium phosphate ceramics can induce bone formation in non-osseous sites without the application of any osteoinductive biomolecules, but the mechanisms of this phenomenon (intrinsic osteoinduction of bioceramics) remain unclear. In this...
作者:Soheila Ali Akbari Ghavimi , Rama Rao Tata , Andrew J. Greenwald ...
来源:[J].The AAPS Journal(IF 4.386), 2017, Vol.19 (4), pp.1029-1044Springer
摘要:Due to the growing number of patients suffering from musculoskeletal defects and the limited supply of and sub-optimal outcomes associated with biological graft materials, novel biomaterials must be created that can function as graft substitutes. For bone regeneration, composite ...
作者:Tatiana A. B. Bressel , Jana Dara Freires de Queiroz , Susana Margarida Gomes Moreira ...
来源:[J].Stem Cell Research & Therapy(IF 3.652), 2017, Vol.8 (1)Springer
摘要:Titanium surfaces have been modified by various approaches with the aim of improving the stimulation of osseointegration. Laser beam (Yb-YAG) treatment is a controllable and flexible approach to modifying surfaces. It creates a complex surface topography with micro and nano-scale...
作者:Pamela Habibovic , Uwe Gbureck , Charles J. Doillon ...
来源:[J].Biomaterials(IF 7.604), 2007, Vol.29 (7), pp.944-953Elsevier
摘要:... The design of the channels allowed investigation of the effect of macropore geometry (open and closed pores) and osteoinduction on bone formation orthotopically. Intramuscular implantation resulted in bone formation within the channels of both monetite and brushite, indicatin...

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