全部文献期刊会议图书|学者科研项目
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作者:Jiongjie Jing , Xiaolong Jiang , Jianwei Chen ...
来源:[J].Animal Reproduction Science(IF 1.897), 2017, Vol.181, pp.69-78
摘要:Abstract(#br)The Notch signaling pathway regulates cell proliferation, differentiation and apoptosis involved in development of the organs and tissues such as nervous system, cartilage, lungs, kidneys and prostate as well as the ovarian follicles. This study aimed to investi...
作者:Cheng-Gen Zheng , Bing-Yu Chen , Ren-Hua Sun ...
来源:[J].Molecular Therapy - Nucleic Acids, 2019
摘要:... The expression of miR-133b was altered or Notch signaling pathway was blocked in the AS mice models in order to evaluate the proliferation, migration and apoptosis of macrophages. It was observed that miR-133b was upregulated in AS, which might target MAML1 to regulate the Notch signaling pathway...
作者:Wei Pan , Xing-Yu Song , Qi-Bo Hu ...
来源:[J].Brain Research(IF 2.879), 2019, Vol.1718, pp.223-230
摘要:... The expression of TSP2, Notch1 and VEGF in MB and adjacent tissues collected from clinical samples as well as a MB cell line (Daoy) was examined. The results demonstrated that in the MB tissues and Daoy cells, TSP2 was downregulated, while Notch1 and VEGF were upregulated. Th...
作者:Ming-ming Ni , Ya-rui Wang , Wen-wen Wu ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2018, Vol.826, pp.66-74
摘要:... The Notch pathway is a fundamental and highly conserved pathway able to control cell-fate, including cell proliferation, differentiation, apoptosis, regeneration and other cellular activities. Recently, the deregulation of Notch cascade has been found involved in many path...
作者:Qifeng Li , Hui Zhang , Liang Yu ...
来源:[J].International Immunopharmacology(IF 2.417), 2018, Vol.54, pp.24-32
摘要:... Notch signaling pathway is involved in the peripheral T cell activation and effector cell differentiation. However, whether it affects Th1/Th2 imbalance in TB patients is still not known. Here, we used γ-secretase inhibitor (DAPT) to treat the peripheral blood mononuclear ...
作者:Chong Liu , Dongxiao Li , Cui Lv ...
来源:[J].Neuroscience(IF 3.122), 2020, Vol.432, pp.84-93
摘要:... The Notch signaling pathway has been reported to be dysfunctional in neurodegenerative diseases, including ALS. However, the exact mechanism is still unclear. Here, we detected Notch signaling activation in proliferating glial cells, Notch inactivation in motor neurons in the...
作者:Yu Wang , Tian-Bao Luo , Long Liu ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.47 (6), pp.2291-2306
摘要:... Thus, an investigation was conducted into the target relationship between LINC00311, which has been reported to be highly expressed in osteoporosis, and delta-like 3 (DLL3), which is involved in the Notch signaling pathway, in connection with a series of bioinformatic methods...
作者:Songou Zhang , Benson O.A. Botchway , Yong Zhang ...
来源:[J].Annals of Anatomy(IF 1.96), 2019, Vol.223, pp.100-107
摘要:... Medicinal and chemical agents have the tendency of regulating signaling pathways. Notch signaling pathway plays an important role in neuronal cell differentiation, neuroinflammation and axonal regeneration in the wake of SCI. Resveratrol has been reported to exert neuroprotec...
作者:Ye Yu , Yuan Wang , Yi Wang ...
来源:[J].Neurotoxicology(IF 2.652), 2018, Vol.68, pp.159-166
摘要:... Thus, the purpose of this study was to determine the effects of marginal ID on the development of cerebellar Bergmann glial cells (BGs) and investigate the activation of the Notch signaling pathway, which is crucial for the development and morphology of BGs. We treated Wi...
作者:Fangkun Shi , Zhiling Dong , Hualian Li ...
来源:[J].Experimental Cell Research(IF 3.557), 2017, Vol.352 (1), pp.1-8
摘要:... Moreover, Notch1 was predicted as a target gene of miR-137 and verified by dual-luciferase reporter assay, real-time quantitative polymerase chain reaction, and western blot analysis. Through targeting of Notch1, miR-137 regulated the Notch signaling pathway. The blockade of ...

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