全部文献期刊会议图书|学者科研项目
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作者:M. Vesel , J. Rapp , D. Feller ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Lung cancer (LC) is still the most common cause of cancer related deaths worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of all LC cases but is not a single entity. It is now accepted that, apart from the characteristic driver mutations, the unique molecular signat...
作者:Michèle Beau-Faller , Erwan Pencreach , Charlotte Leduc ...
来源:[J].Lung Cancer(IF 3.392), 2020, Vol.140, pp.19-26
摘要:Abstract(#br)Objectives(#br)T790M mutations in EGFR -mutated non-small cell lung cancer (NSCLC) account for nearly 50% of acquired resistance mechanisms to EGFR-TKIs. Earlier studies suggested that tumor T790M could also be detected in TKI-naïve EGFR -mutated NSCLC. The aim ...
作者:Lingfei Tong , Wenming Wu
来源:[J].Pathology - Research and Practice(IF 1.213), 2019, Vol.215 (9)
摘要:Abstract(#br)Objectives(#br)This study was aimed to investigate the effects of long non-coding RNA (lncRNA) cancer susceptibility candidate 2c (CASC2c) on the proliferation, metastasis and drug resistance of non-small cell lung cancer (NSCLC) cells.(#br)Methods(#br)The expressi...
作者:Alessandro Leonetti , Francesco Facchinetti , Giulio Rossi ...
来源:[J].Cancer Treatment Reviews(IF 6.024), 2018, Vol.66, pp.82-94
摘要:Abstract(#br)Molecular characterization of non-small cell lung cancer (NSCLC) marked an historical turning point for the treatment of lung tumors harboring kinase alterations suitable for specific targeted drugs inhibition, translating into major clinical improvements. Besides ...
作者:Aaron C. Tan , Gillianne G.Y. Lai , Gek San Tan ...
来源:[J].Lung Cancer(IF 3.392), 2020, Vol.139, pp.207-215
摘要:Abstract(#br)Objectives(#br)There is an expanding list of therapeutically relevant biomarkers for non-small cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition in scaling traditional single biomarker assays from small biopsies is an incre...
作者:Hui Zhao , Yan Duan , Tanzhen Liu ...
来源:[J].Biotechnology & Biotechnological Equipment(IF 0.622), 2019, Vol.33 (1), pp.894-901
摘要:The aim of this study was to investigate the role of chromatin assembly factor 1 subunit A (CHAF1A) in the pathogenesis of non-small cell lung cancer (NSCLC), as well as its association with disease prognosis. The expression levels of CHAF1A in NSCLC tissues were detected by immu...
作者:Kazuo Nakagawa , Hisao Asamura , Koji Tsuta ...
来源:[J].Lung Cancer(IF 3.392), 2016, Vol.97, pp.1-7
摘要:Abstract(#br)Objectives(#br)The precise and rapid diagnosis of the presence or absence of lymph node (LN) metastasis is essential for deciding upon an appropriate therapeutic strategy for patients with non-small cell lung cancer (NSCLC). We conducted a prospective multicenter...
作者:Qin Shen , Xuan Wang , Bo Yu ...
来源:[J].Lung Cancer(IF 3.392), 2015, Vol.90 (3), pp.492-498
摘要:Abstract(#br)Objectives(#br)Anaplastic lymphoma kinase ( ALK )-rearranged non-small cell lung cancer (NSCLC) screening is essential to its treatment such as crizotinib. Different assays have been developed to detect ALK rearrangements, such as fluorescence in situ hybridization...
作者:Victoria Dunne , Mihaela Ghita , Donna M. Small ...
来源:[J].Radiotherapy and Oncology(IF 4.52), 2017
摘要:Abstract(#br)Background and purpose(#br)To evaluate the impact of ATR inhibition using AZD6738 in combination with radiotherapy on the response of non-small cell lung cancer (NSCLC) tumour models and a murine model of radiation induced fibrosis.(#br)Materials and methods(#br)AZD6...
作者:Juliane Rieber , Alexander Deeg , Elena Ullrich ...
来源:[J].Lung Cancer(IF 3.392), 2016, Vol.91, pp.41-47
摘要:Abstract(#br)Purpose(#br)Current guidelines recommend postoperative radiation therapy (PORT) for incompletely resected non-small cell lung cancer (NSCLC). However, there is still a paucity of evidence for this approach. Hence, we analyzed survival in 78 patients following radio...

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