全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Neves G. , Fenner R. , Heckler A.P. ...
来源:[J].Brazilian Journal of Medical and Biological Research(IF 1.139), 2003, Vol.36 (5), pp.625DOAJ
摘要:... The aim of the present study was to report the structural design of two N-phenylpiperazine derivatives, compound 4: 1-[1-(4-chlorophenyl)-1H-4-pyrazolylmethyl]-4-phenylhexahydropyrazine and compound 5: 1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-ylmethyl]-4-phenylhexahydropyrazi...
作者:G. Neves , R. Fenner , A.P. Heckler ...
来源:[J].Brazilian Journal of Medical and Biological Research(IF 1.139), 2003, Vol.36 (5), pp.625-629DOAJ
摘要:... The aim of the present study was to report the structural design of two N-phenylpiperazine derivatives, compound 4: 1-[1-(4-chlorophenyl)-1H-4-pyrazolylmethyl]-4-phenylhexahydropyrazine and compound 5: 1-[1-(4-chlorophenyl)-1H-1,2,3-triazol-4-ylmethyl]-4-phenylhexahydropyrazi...
作者:Ivan Malík , Marián Bukovský , Fils Andriamainty ...
来源:[J].Brazilian Journal of Microbiology(IF 0.762), 2012, Vol.43 (3), pp.959-965DOAJ
摘要:In the present investigation, the basic esters of meta-alkoxyphenylcarbamic acid bearing variously substituted N-phenylpiperazine fragment were screened for their in vitro antimicrobial activity against Staphylococcus aureus, Escherichia coli and Candida albicans, respectively. ...
作者:Seyedeh M. Mahdavi , Azizollah Habibi , Hadi Dolati ...
来源:[J].Letters in Organic Chemistry(IF 0.667), 2016, Vol.13 (4), pp.316-321Bentham
摘要:... Methods: We synthesized new derivatives of spirooxindole by a three-component reaction of isatinderivatives, malononitrile (or ethyl cyanoacetate) and beta-dicarbonyl compounds in the presence ofcatalytic amount of N-Phenylpiperazine (NPP) as an organocatalyst. Results: A ser...
作者:Daniela J. Conrado , Stela Maris Kuze Rates , Teresa Dalla Costa ...
来源:[J].Química Nova(IF 0.737), 2007, Vol.30 (8), pp.1919-1922DOAJ
摘要:A rapid HPLC analytical method was developed and validated for the determination of the N-phenylpiperazine derivative LASSBio-579in plasma rat. Analyses were performed using a C18 column and elution with 20 mM sodium dihydrogen phosphate monohydrate - methanol. The analyte was mo...
作者:Özlem Sarıöz , Sena Öznergiz , Fatma Kandemirli
来源:[J].Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry(IF 0.144), 2013, Vol.43 (2), pp.185-195Taylor & Francis
摘要:Functionalized bis(amino)phosphines that are the type PhP(NR2)2 (1,2) have been synthesized by treating PhPCl2 with N-phenylpiperazine or N-ethylpiperazine. Ligands react with aqueous hydrogen peroxide, elemental sulfur, or selenium to give the...
作者:V. S. Reznik , V. D. Akamsin , I. V. Galyametdinova
来源:[J].Russian Chemical Bulletin(IF 0.423), 2001, Vol.50 (1), pp.125-129Springer
摘要:Abstract(#br)The reactions of 3-chloropropylphosphonates, 3-chloropropylthiophosphonates, or 3-chloropropylphosphinates with 2-aryloxyethylamines or N -phenylpiperazine afford the corresponding 3-(2-aryloxyethylamino)propylphosphonates and -phosphinates or 3-(4-phenylpiperaz...
作者:Jerzy Kossakowski , Anna Bielenica , Marta Struga ...
来源:[J].Medicinal Chemistry Research(IF 1.612), 2008, Vol.17 (8), pp.507-514Springer
摘要:Abstract(#br)The synthesis and pharmacological activity of 4-[2-hydroxy-3-(4-phenyl-piperazin-1-yl)-propoxy]-4-aza-tricyclo[5.2.1.0 2,6 ]dec-8-ene-3,5-dione is described. The structure of the compound was confirmed by elemental analysis, 1 H nuclear magnetic resonance (NMR), 13 C...
作者:Tatiana F. Gomes , Thais E.T. Pompeu , Daniel A. Rodrigues ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2013, Vol.62, pp.214-221Elsevier
摘要:Abstract(#br)Using a combination of docking and molecular dynamics simulations, we predicted that p -hydroxylation by CYP1A2 would be the main metabolic pathway for the 1-[1-(4-chlorophenyl)-1 H -4pyrazolylmethyl] phenylhexahydropiperazine, LASSBio-579 ( 3 ). As the result of a s...

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