作者:Junpeng Zhang , Thuc D Le , Lin Liu ... |
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (3)Springer |
摘要:MicroRNA (miRNA) sponges with multiple tandem miRNA binding sequences can sequester miRNAs from their endogenous target mRNAs. Therefore, miRNA sponge acting as a decoy is extremely important for long-term loss-of-function studies both in vivo and in silico . Recently, a growing ... |
作者:Junpeng Zhang , Thuc Duy Le , Lin Liu ... |
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer |
摘要:Recent studies have shown that the crosstalk between microRNA (miRNA) sponges plays an important role in human cancers. However, the co-regulation roles of miRNA sponges in protein-protein interactions (PPIs) are still unknown. |
作者:Manu Shivakumar , Younghee Lee , Lisa Bang ... |
来源:[J].BMC Medical Genomics(IF 3.466), 2017, Vol.10 (1)Springer |
摘要:... In addition, miRNA, another major component of epigenome, is also a regulator at the post-transcriptional levels that modulate transcriptome changes. However, a mechanistic role of synergistic interactions between DNA methylation and miRNA as epigenetic regulators on transcri... |
作者:Qiansi Chen , Meng Li , Zhongchun Zhang ... |
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer |
摘要:Drought stress is one of the most severe problem limited agricultural productivity worldwide. It has been reported that plants response to drought-stress by sophisticated mechanisms at both transcriptional and post-transcriptional levels. However, the precise molecular mechanisms... |
作者:Showkat Ahmad Ganie , Ananda Bhusan Debnath , Abubakar Mohammad Gumi ... |
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer |
摘要:MicroRNAs (miRNAs) are non-coding RNAs that play versatile roles in post-transcriptional gene regulation. Although much is known about their biogenesis, and gene regulation very little is known about their evolutionary relation among the closely related species. |
作者:Shomi Oka , Hiroshi Furukawa , Kota Shimada ... |
来源:[J].BMC Musculoskeletal Disorders(IF 1.875), 2017, Vol.18 (1)Springer |
摘要:Interstitial lung disease (ILD) is frequently associated with rheumatoid arthritis (RA), and is designated RA-associated ILD (RA-ILD). RA-ILD has a large impact on the prognosis of RA. Here, we investigated the micro RNAs (miRNAs) profiles to determine whether they may be useful ... |
作者:Mario Baumgart , Emanuel Barth , Aurora Savino ... |
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer |
摘要:The short-lived fish Nothobranchius furzeri is the shortest-lived vertebrate that can be cultured in captivity and was recently established as a model organism for aging research. Small non-coding RNAs, especially miRNAs, are implicated in age dependent control of gene expression... |
作者:Yan Y , Li XQ , Duan JL ... |
来源:[J].International Journal of Nanomedicine(IF 3.463), 2019, Vol.Volume 14, pp.3645-3667DOAJ |
摘要:...Methods: A novel 25 nucleotide sense strand of miRNA was designed to treat TNBC by silencing the Slug gene, and encapsulated into DSPE-PEG2000-tLyp-1 peptide-modified functional liposomes. The efficacy of miRNA liposomes was evaluated on invasive TNBC cells and TNBC cancer-b... |
作者:Shanrong Zhao , William Gordon , Sarah Du ... |
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer |
摘要:Genome-wide miRNA expression data can be used to study miRNA dysregulation comprehensively. Although many open-source tools for microRNA (miRNA)-seq data analyses are available, challenges remain in accurate miRNA quantification from large-scale miRNA-seq dataset. We implemented ... |
作者:Abdul Fatah A. Samad , Reyhaneh Rahnamaie-Tajadod , Muhammad Sajad ... |
来源:[J].BMC Genomics(IF 4.397), 2019, Vol.20 (1), pp.1-22DOAJ |
摘要:... minor have been studied thoroughly, the involvement of microRNA (miRNA) in terpenoid regulation remains poorly understood and needs to be explored. In this study, P. minor plants were inoculated with the pathogenic fungus Fusarium oxysporum for terpenoid induction. Result SP... |
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