全部文献期刊会议图书|学者科研项目
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作者:Camilla Pramfalk , Tomas Jakobsson , Cristy R.C. Verzijl ...
来源:[J].BBA - Molecular and Cell Biology of Lipids(IF 4.134), 2020, Vol.1865 (6)
摘要:... Here, we aimed to create hepatocyte-like cells expressing the ACAT2, but not the ACAT1, protein to generate a model that – at least in this regard – resembles the human condition in vivo and to assess the effects on lipid metabolism. Using the Clustered Regularly Int...
作者:Xue Li , Junping Wu , Xin Sun ...
来源:[J].Stem Cell Reports, 2020, Vol.14 (3), pp.420-432
摘要:... Mechanistically, during bleomycin injury, autophagy downregulated lipid metabolism but upregulated glucose metabolism in AT2 cells for alveolar repair. Chemical blockade of fatty acid synthesis promoted organoid growth of AT2 cells and counteracted the effects of autophagy lo...
作者:Qiaoling Yang , Fangfang Shu , Junting Gong ...
来源:[J].Journal of Ethnopharmacology(IF 2.755), 2020, Vol.255
摘要:... Ingenuity pathway analysis (IPA) demonstrated that hepatic gene networks related to lipid metabolism and inflammatory response were down-regulated in the HFD + sweroside group. PPAR-ɑ was located in the center of the hepatic gene network, and the significantly altered g...
作者:Mei-Fang Li , Li Ma , Tian-Pei Yu ...
来源:[J].Diabetes Research and Clinical Practice(IF 2.741), 2020, Vol.161
摘要:Abstract(#br)Aims(#br)To assess the prevalence and risk of adverse perinatal outcomes in pregnant women with abnormal glucose metabolism.(#br)Methods(#br)3269 Chinese pregnant women with singleton delivery were studied, including 787 diagnosed as gestational diabetes mellitus...
作者:Su Yon Jung , Eric M. Sobel , Jeanette C. Papp ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Impaired glucose metabolism–related genetic variants and traits likely interact with obesity and related lifestyle factors, influencing postmenopausal breast and colorectal cancer (CRC), but their interconnected pathways are not fully understood. By stratifying via obesity and...
作者:Jessica K. Van Harsselaar , Julia Lorenz , Melanie Senning ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:... Its metabolism has been subject of extensive research over the past decades. Despite its importance, a description of the complete inventory of genes involved in starch metabolism and their genome organization in potato plants is still missing. Moreover, mechanisms regulating...
作者:Hui Chen , Yanli Zheng , Jiao Zhan ...
来源:[J].Biotechnology for Biofuels(IF 5.552), 2017, Vol.10 (1)Springer
摘要:... For instance, lipid metabolism can be induced by nitrogen-limiting conditions. However, the underlying mechanisms of lipid biosynthesis are unclear. In this study, we analyzed the global metabolic profiles of three genetically closely related Chlorella strains (C1, C2, and C...
作者:Katja Uršič , Mojca Ogrizović , Dušan Kordiš ...
来源:[J].BMC Microbiology(IF 3.104), 2017, Vol.17 (1)Springer
摘要:... To assess the role of Tum1 in cell metabolism and the putative functional connection between lipid metabolism and tRNA modification, we analysed evolutionary conservation of the rhodanese protein superfamily, investigated the role of Tum1 in lipid metabolism, and examined the...
作者:Tanya R. Copley , Konstantinos A. Aliferis , Daniel J. Kliebenstein ...
来源:[J].BMC Plant Biology(IF 4.354), 2017, Vol.17 (1)Springer
摘要:... Combining information from different “omics” levels such as transcriptomics, metabolomics, and proteomics is required to gain insights into plant metabolism and its regulation. As such, we studied fluctuations in soybean metabolism in response to R. solani infection at e...
作者:Valery Veprinskiy , Leonhard Heizinger , Maximilian G. Plach ...
来源:[J].BMC Evolutionary Biology(IF 3.285), 2017, Vol.17 (1)Springer
摘要:... For a high-level classification, metabolism is subdivided into primary (PM) and secondary (SM) metabolism. SM products are often not essential for survival of the organism and it is generally assumed that SM enzymes stem from PM homologs.

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