全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Xiao-Dan Ren , Ying-Wen Zhang , Xiu-Ping Wang ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
摘要:Dysfunction of glomerular mesangial cells (GMCs) plays an important role in pathogenesis of diabetic nephropathy. Here, we investigated the effects of Dangguibuxue decoction (DBD), an herbal traditional Chinese medicinal (TCM) formula composed of Astragali Radix and Angelicae Sin...
作者:Nuoyan Zheng , Donxian Wang , Hongyan Ming ...
来源:[J].BMC Nephrology(IF 1.644), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)B cell activating factor belonging to the TNF family (BAFF) is vital for B cell survival, proliferation and activation. Evidence indicates that BAFF is systemically or locally increased in glomerulonephritis (e.g. lupus nephritis, IgA nephropathy). ...
作者:Jin-Shuen Chen , Herng-Sheng Lee , Jong-Shiaw Jin ...
来源:[J].Journal of Biomedical Science(IF 2.458), 2004, Vol.11 (2), pp.142-151Springer
摘要:Abstract(#br)Hyperglycemia and mannitol activate protein kinase C (PKC) and induce mesangial cell hypocontractility that subsequently may modulate renal function. Since focal adhesion kinase (FAK) activation is known to be linked with PKC activity, FAK may also be involved in mesangial cell...
作者:Min-Jung Park , Ho Jae Han , Dong-il Kim
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2017, Vol.18 (7)DOAJ
摘要:Lipotoxicity-induced mesangial cell apoptosis is implicated in the exacerbation of diabetic nephropathy (DN). Protein arginine methyltransferases (PRMTs) have been known to regulate a variety of biological functions. Recently, it was reported that PRMT1 expression is increased in...
作者:Wenjia Geng , Ribao Wei , Shuwen Liu ...
来源:[J].Biological Research(IF 1.129), 2018, Vol.49, pp.1-10DOAJ
摘要:BACKGROUND: In China, mesangial proliferative glomerulonephritis (MsPGN) is one of the most common kidney diseases. In this study, we treated a rat model of chronic anti-Thy-1 MsPGN with Shenhua Tablet and evaluated whether the tablet was able to protect the kidney function. Thir...
作者:Tao Ding , Wei Chen , Juan Li ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.41 (3), pp.1035-1043DOAJ
摘要:Background/Aims: Overproliferation of mesangial cells was believed to play an important role in the progress of diabetic nephropathy, one of the primary complications of diabetes. Hydrogen sulfide (H2S), a well-known and pungent gas with the distinctive smell of rotten eggs, was ...
作者:Kang Ding , Yan Wang , Weimin Jiang ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2015, Vol.15 (1)Springer
摘要:... In this study, we investigated the effects of QYYYG-containing serum (QYGS) in human mesangial cells (HMCs) against Ang II-induced cell proliferation, ROS production, and inflammation through the seropharmacological method.(#br) Results(#br)We found that QYGS could inhibit cell...
作者:Kerstin Ebefors , Peidi Liu , Emelie Lassén ...
来源:[J].BMC Nephrology(IF 1.644), 2016, Vol.17 (1)Springer
摘要:... We hypothesize that, in addition to IgA complexes, patients with IgAN possess a subtype of mesangial cells highly susceptible to gd-IgA induced cell proliferation.(#br) Methods(#br)To test the hypothesis, we designed a technique to culture primary mesangial cells from rena...
作者:Honglan Piao , Yuan Chi , Xiling Zhang ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2016, Vol.132 (4), pp.224-234Elsevier
摘要:Abstract(#br)Suramin inhibits immune responses and protects cells against inflammatory cell injury. However, little is known about its mechanisms. Using an in vitro model of glomerular mesangial cell (MC) lysis induced by antibodies plus complement, we investigated the potential ...
作者:Shuzhen Li , Zhenzhen Sun , Guixia Ding ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.43 (1), pp.271-281DOAJ
摘要:Background/Aims: We previously reported that indoxyl sulfate (IS) could cause mesangial cell (MC) proliferation via a cyclooxygenase (COX)-2-dependent mechanism. However, the specific prostaglandin contributing to COX-2 effect on IS-induced MC proliferation remained unknown. T...

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