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作者:Norbertus A. Ipenburg , Serigne N. Lo , Ricardo E. Vilain ...
来源:[J].Journal of the American Academy of Dermatology(IF 4.906), 2020, Vol.82 (4), pp.910-919
摘要:Background(#br)Mitotic rate is a strong predictor of outcome in adult patients with primary cutaneous melanoma, but for children and adolescent patients this is unknown.(#br)Objective(#br)We sought to assess the prognostic value of primary tumor mitotic rate in children and ...
作者:Yislenz Narváez-Martínez , Napoleón de la Ossa , Raquel López-Martos ...
来源:[J].Neurocirugía(IF 0.343), 2017, Vol.28 (4), pp.190-196Elsevier
摘要:... Several entities have to be considered, including melanin-containing tumours (melanotic ependymoma and melanotic schwannoma) and melanocyte-containing tumours (melanocytoma, primary melanoma and melanoma metastases). The case is presented of a 47 year-old male with a pigmente...
作者:Raghavendra Gowda , Bailey M. Robertson , Soumya Iyer ...
来源:[J].Cancer Treatment Reviews(IF 6.024), 2020, Vol.85
摘要:Abstract(#br)The mechanisms of melanoma metastasis have been the subject of extensive research for decades. Improved diagnostic and therapeutic strategies are of increasing importance for the treatment of melanoma due to its high burden of mortality in the advanced stages of the ...
作者:Yo-Han Han , Jeong-Geon Mun , Hee Dong Jeon ...
来源:[J].Phytomedicine(IF 2.972), 2020, Vol.68
摘要:...A on metastatic melanoma, and the mechanism by which it affects metastatic melanoma.(#br)Study design(#br)The anti-proliferative and anti-metastatic effects of G.A were observed in in vitro and in vivo .(#br)Methods(#br)WST assay and flow cytometry were conducted to invest...
作者:Yeong-Seon Won , Kwon-Il Seo
来源:[J].Food and Chemical Toxicology(IF 3.01), 2020, Vol.138
摘要:... The molecular and cellular mechanisms of sanggenol L effects on melanoma cells are not well known. Recently, melanoma is the most common skin cancer with a high mortality rate not only in United States, but also in East Asia. Therefore, safe and effective treatments for melanoma...
作者:Priscila Daniele Ramos Cirilo , Luciana Nogueira de Sousa Andrade , Bruna Renata Silva Corrêa ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Melanoma is the most lethal type of skin cancer. Since chemoresistance is a significant barrier, identification of regulators affecting chemosensitivity is necessary in order to create new forms of intervention. Prohibitin 1 (PHB1) can act as anti-apoptotic or tumor suppressor mo...
作者:Liang Song , Ewan M. McNeil , Ann-Marie Ritchie ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:The global incidence of melanoma has been increasing faster than any other form of cancer. New therapies offer exciting prospects for improved survival, but the development of resistance is a major problem and there remains a need for additional effective melanoma therapy. Platin...
作者:Messaouda Merzoug-Larabi , Caroline Spasojevic , Marianne Eymard ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Melanoma is a highly metastatic type of cancer that is resistant to all standard anticancer therapies and thus has a poor prognosis. Therefore, metastatic melanoma represents a significant clinical problem and requires novel and effective targeted therapies. The protein kinase C ...
作者:Jérôme Fernandes , Bruno Bregman , Patrick Combemale ...
来源:[J].BMC Health Services Research(IF 1.773), 2017, Vol.17 (1)Springer
摘要:Management of metastatic melanoma is changing rapidly following the introduction of innovative effective therapies, with consequences for the allocation of healthcare resources. The objective of this study was to assess hospitalisation costs of metastatic melanoma in France from ...
作者:Selma Ugurel , Joachim Röhmel , Paolo A. Ascierto ...
来源:[J].European Journal of Cancer(IF 5.061), 2020, Vol.130, pp.126-138
摘要:Abstract(#br)Background(#br)Recent therapeutic strategies, particularly MAP kinase pathway inhibitors (BRAF, MEK) and immune checkpoint blockers (CTLA-4, PD-1), have been put on the test for their differential impact on long-term survival of metastatic melanoma patients. Vari...

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