全部文献期刊会议图书|学者科研项目
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作者:Chatterjee Amit , Prema Padmanabhan , Sailaja V. Elchuri ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2020
摘要:Abstract(#br)Matrix stiffness regulates the physiology of the cells and plays an important role in maintaining its homeostasis. It has been reported to regulate cell division, proliferation, migration, extracellular uptake and various other physiological processes. The alteration...
作者:Jun Dai , Liang Qin , Yan Chen ...
来源:[J].Journal of the Mechanical Behavior of Biomedical Materials(IF 2.368), 2018
摘要:Abstract(#br)Matrix stiffness is known to alter cellular behaviors in various biological contexts. Previous investigations have shown that epithelial–mesenchymal transition (EMT) promotes the progression and invasion of tumor. Mechanical signaling is identified as a regulat...
作者:Chang Liu , Jing-Wan Luo , Ting Liang ...
来源:[J].Experimental Cell Research(IF 3.557), 2018
摘要:... Matrix stiffness modulated stem cells differentiation, and matrix stiffness of tendinopathic tissues decreased significantly. In order to clarify the role of matrix stiffness in TDSCs differentiaiton, they were cultured on the gelatin hydrogels with the stiffness from 2.34...
作者:Baoxiang Tian , Xili Ding , Yang Song ...
来源:[J].Biomaterials(IF 7.604), 2019, Vol.221
摘要:Abstract(#br)The stiffness change of the vessel wall is involved in many pathological processes of the blood vessel. However, how stiffness changes regulate vascular cell phenotype is not well understood. In this study, we investigated the effects of matrix stiffness on the ph...
作者:Yinying Dong , Xiaoying Xie , Zhiming Wang ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2014, Vol.444 (3), pp.427-432
摘要:Abstract(#br)Matrix stiffness as a novel regulation factor involves in modulating the pathogenesis of hepatocellular carcinoma (HCC) invasion or metastasis. However, the mechanism by which matrix stiffness modulates HCC angiogenesis remains unknown. Here, using buffalo rat H...
作者:Chang Liu , Yang Liu , Xiao-xi Xu ...
来源:[J].Experimental Cell Research(IF 3.557), 2015, Vol.330 (1), pp.123-134
摘要:... In this study, the potential effect of matrix stiffness on the biological characteristics of human head and neck squamous cell carcinoma (HNSCC) TICs, especially the enrichment of HNSCC TICs, was investigated under three-dimensional (3D) culture conditions by means of alginat...
作者:Yosi Navaro , Nadav Bleich-Kimelman , Lena Hazanov ...
来源:[J].Biomaterials(IF 7.604), 2015, Vol.49, pp.68-76
摘要:... It was recently shown that survival and function of mature NP cells are regulated in part by tissue stiffness. We hypothesized that modification of matrix stiffness will influence the ability of cultured NP-SCs to proliferate, survive, and differentiate into mature NP cells...
作者:Brahmananda Reddy Chitteti , Melissa A. Kacena , Sherry L. Voytik-Harbin ...
来源:[J].Journal of Immunological Methods(IF 2.225), 2015, Vol.425, pp.108-113
摘要:Abstract(#br)To recreate the in vivo hematopoietic cell microenvironment or niche and to study the impact of extracellular matrix (ECM) biophysical properties on hematopoietic progenitor cell (HPC) proliferation and function, mouse bone-marrow derived HPC (Lin-Sca1+cKit+/(LSK) w...
作者:Juanjuan Xu , Meiyu Sun , Ye Tan ...
来源:[J].Differentiation(IF 2.855), 2017, Vol.96, pp.30-39
摘要:... Matrix stiffness plays a profound role on stem cell behavior. Nevertheless, the effect of matrix stiffness on umbilical cordmesenchymal stem cells (UC-MSCs) remains unexplored. To conduct an in-depth exploration, we cultured UC-MSCs on different stiffness (Young's modulus: 1...
作者:Murali Ganesan , Raghubendra Singh Dagur , Edward Makarov ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2018, Vol.500 (3), pp.717-722
摘要:... In this study, we hypothesize that increased matrix stiffness enhances apoptosis in HCV-HIV-co-infected hepatocytes and that capturing of apoptotic bodies (AB) derived from these infected hepatocytes by hepatic stellate cells (HSC) drives the fibrosis progression. As the sour...

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