全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Chiara Lauritano , Maria Immacolata Ferrante , Alessandra Rogato
来源:[J].Marine Drugs(IF 3.978), 2019, Vol.17 (5)DOAJ
摘要:... Marine microalgae possess distinct and unique metabolic pathways, and can potentially produce specific secondary metabolites with biological activity (e.g., antipredator, allelopathic, antiproliferative, cytotoxic, anticancer, photoprotective, as well as anti-infective and an...
作者:Hassan Y. Ebrahim , Khalid A. El Sayed
来源:[J].Marine Drugs(IF 3.978), 2016, Vol.14 (3)DOAJ
摘要:Marine natural products (MNPs) are recognized for their structural complexity, diversity, and novelty. The vast majority of MNPs are pharmacologically relevant through their ability to modulate macromolecular targets underlying human diseases. Angiogenesis is a fundamental proc...
作者:Yiwen Hu , Jiahui Chen , Guping Hu ...
来源:[J].Marine Drugs(IF 3.978), 2015, Vol.13 (1), pp.202-221DOAJ
摘要:Every year, hundreds of new compounds are discovered from the metabolites of marine organisms. Finding new and useful compounds is one of the crucial drivers for this field of research. Here we describe the statistics of bioactive compounds discovered from marine organisms from 1...
作者:Solida Long , Emília Sousa , Anake Kijjoa ...
来源:[J].Molecules(IF 2.428), 2016, Vol.21 (7)DOAJ
摘要:... On the other hand, a strategy to search for modulators from natural products to overcome MDR had been in place during the last decades. However, Nature limits the amount of some natural products, which has led to the development of synthetic strategies to increase their avail...
作者:Chun-Yu Chen , Yung-Fong Tsai , Wen-Yi Chang ...
来源:[J].Marine Drugs(IF 3.978), 2016, Vol.14 (8)DOAJ
摘要:... Marine organisms are a valuable source of bioactive compounds with potential for industrial and pharmaceutical application. Marine natural products that inhibit neutrophil activation could be used as drugs for the treatment of inflammatory diseases. Numerous studies investiga...
作者:Lilia Cherigo , Dioxelis Lopez , Sergio Martinez-Luis
来源:[J].Marine Drugs(IF 3.978), 2015, Vol.13 (4), pp.2010-2029DOAJ
摘要:... This review article aims to summarize the different research findings on marine natural products with BCRP inhibiting activity. In this sense, the potential modulation of physiological targets of BCRP by natural or synthetic compounds offers a great possibility for the discov...
作者:Chen Zhang , Se-Kwon Kim
来源:[J].Marine Drugs(IF 3.978), 2009, Vol.7 (2), pp.71DOAJ
摘要:... Up to present, more than 20,000 new compounds have been isolated from marine organisms, where considerable numbers of these naturally occurring derivatives are developed as potential candidates for pharmaceutical application. Eventhough the quantity of marine derived MMPIs is...
作者:Yoshihide Usami
来源:[J].Marine Drugs(IF 3.978), 2009, Vol.7 (3), pp.314DOAJ
摘要:Because of the highly unique structures of marine natural products, there are many examples of structures that were originally proposed based on spectral analyses but later proven incorrect. In many cases, the total syntheses of the originally proposed structures of marine natural products...
作者:Amy J. Jones , Tanja Grkovic , Melissa L. Sykes ...
来源:[J].Marine Drugs(IF 3.978), 2013, Vol.11 (10), pp.4058-4082DOAJ
摘要:Marine natural products are a diverse, unique collection of compounds with immense therapeutic potential. This has resulted in these molecules being evaluated for a number of different disease indications including the neglected protozoan diseases, human African trypanosomiasis a...
作者:Ana Martins , Helena Vieira , Helena Gaspar ...
来源:[J].Marine Drugs(IF 3.978), 2014, Vol.12 (2), pp.1066-1101DOAJ
摘要:The marine environment harbors a number of macro and micro organisms that have developed unique metabolic abilities to ensure their survival in diverse and hostile habitats, resulting in the biosynthesis of an array of secondary metabolites with specific activities. Several of th...

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