全部文献期刊会议图书|学者科研项目
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作者:Yu Xia , Peng-Cheng Cai , Fan Yu ...
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Mucus overproduction is an important feature of asthma. Interleukin (IL)-4 is required for allergen-induced airway inflammation and mucus production. MUC5AC gene expression is regulated by transcript factors NF-κB. The intracellular Ca2+ ([Ca2+]i...
作者:Irene Izquierdo , María N. Barrachina , Lidia Hermida-Nogueira ...
来源:[J].Journal of Proteomics(IF 4.088), 2019, Vol.195, pp.88-97
摘要:Abstract(#br)Lipid rafts are membrane microdomains that have been proposed to play an important role in several platelet-signalling cascades, including those mediated by the receptors Glycoprotein VI (GPVI), and C-type lectin domain family 1 member B (CLEC-2), both involved in th...
作者:Huaming Xu , Yuan Liu , Dongsheng Wang ...
来源:[J].Journal of Ethnopharmacology(IF 2.755), 2019, Vol.237, pp.55-63
摘要:... TJ proteins are associated with cholesterol-enriched regions of plasma membrane known as lipid rafts, which are critical for the trafficking, positioning and function of TJ proteins. In this study, we investigated the effect of SMI on the expression and trafficking of the key...
作者:Raquel Marin , Noemí Fabelo , Virginia Martín ...
来源:[J].Neurobiology of Aging(IF 6.166), 2017, Vol.49, pp.52-59
摘要:Abstract(#br)Lipid rafts are highly dynamic membrane microdomains intimately associated with cell signaling. Compelling evidence has demonstrated that alterations in lipid rafts are associated with neurodegenerative diseases such Alzheimer's disease, but at present, whether al...
作者:Yunhe Jiang , Shunan Liu , Siyu Shen ...
来源:[J].Antiviral Research(IF 3.925), 2020, Vol.176
摘要:... Here, we show that methyl-β-cyclodextrin (MβCD), a common drug that disrupts lipid rafts, specifically inhibits EV-D68 infection without producing significant cytotoxicity at virucidal concentrations. The addition of exogenous cholesterol attenuated the anti-EV-D68 activit...
作者:Mario Díaz , Noemí Fabelo , Isidre Ferrer ...
来源:[J].Neurobiology of Aging(IF 6.166), 2018, Vol.67, pp.42-52
摘要:Abstract(#br)Lipid rafts are highly dynamic membrane domains featured by distinctive biochemical composition and physicochemical properties compared with the surrounding plasma membrane. These microstructures are associated not only with cellular signaling and communication in n...
作者:S.M Campbell , S.M Crowe , J Mak
来源:[J].Journal of Clinical Virology(IF 3.287), 2001, Vol.22 (3), pp.217-227
摘要:Abstract(#br)Background: Lipid rafts are currently an intensely investigated topic of cell biology. In addition to a demonstrated role in signal transduction of the host cell, lipid rafts serve as entry and exit sites for microbial pathogens and toxins, such as FimH-expressing en...
作者:Stephen R. Wassall , Xiaoling Leng , Samuel W. Canner ...
来源:[J].BBA - Biomembranes(IF 3.389), 2018
摘要:... One structural mechanism by which DHA exerts its biological effects is through its ability to modify the physical organization of plasma membrane signaling assemblies known as sphingomyelin/cholesterol (SM/chol)-enriched lipid rafts. Here we studied how DHA acyl chains es...
作者:Wei Zhu , Xiangyi Deng , Jinming Peng ...
来源:[J].The Journal of Nutritional Biochemistry(IF 4.552), 2017, Vol.48, pp.62-73
摘要:... In the synthetic “lipid raft-like” liposome, A-type ECG and EGCG dimers incorporated into the liposome with high affinity and decreased the fluidity of the liposome. In 3T3-L1 preadipocytes, A-type ECG and EGCG dimers possibly bonded to lipid rafts cholesterol and dis...
作者:Yao Lv , Duo Zhou , Xiao-qiang Hao ...
来源:[J].Cancer Letters(IF 4.258), 2019, Vol.460, pp.108-118
摘要:... Furthermore, lipid rafts, a type of membrane microdomain with specific lipid compositions, played an important role in facilitating entry of rMV-Hu191. Integrity of lipid rafts was required for successful viral infection as well as subsequent cell apoptosis, but was not requi...

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