全部文献期刊会议图书|学者科研项目
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作者:Jing Liu , Bo Jin , Hang Su ...
来源:[J].BMC Cancer(IF 3.333), 2019, Vol.19 (1), pp.1-6DOAJ
摘要:... Case presentation A 65-year-old female patient was diagnosed with stage IV non-small-cell lung adenocarcinoma with synchronic brain metastasis in February 2015. Before and during treatment, 416 tumor-related genes were monitored dynamically by liquid biopsies using next-gener...
作者:Yanfang Ju , Jinliang Wang , Shengjie Sun ...
来源:[J].Journal of Cancer Research and Therapeutics(IF 0.761), 2016, Vol.12 (7), pp.181-185DOAJ
摘要:Objective: Leptomeningeal metastasis (LM) leades a devastating consequence in patients with nonsmall cell lung cancer(NSCLC). Treatment is very limited for patients with LM. We introduced to use nimotuzumab (also known as h-R3) combined with methotrexate for treating LM in NS...
作者:MingShan Zhang , YunWei Ou , HongWei Zhang ...
来源:[J].Chinese Science Bulletin(IF 1.319), 2012, Vol.57 (22), pp.2914-2919Springer
摘要:Abstract(#br)Leptomeningeal metastasis (LM) is caused by the spread of malignant tumor cells into the subarachnoid space. However, classification and staging of LM in the spinal canal is rare in the literature. The authors reviewed the records of 58 Chinese patients with LM for...
作者:Emilie Le Rhun , Roberta Rudà , Patrick Devos ...
来源:[J].Journal of Neuro-Oncology(IF 3.115), 2017, Vol.133 (2), pp.419-427Springer
摘要:Leptomeningeal metastases are a late manifestation of systemic cancer which affects up to 10% of patients with solid tumors. Prognosis is poor, and overall survival at 1 year is only approximately 10%. Management depends mainly on general and neurological condition, primary tumor...
作者:Iole Cordone , Serena Masi , Valentina Summa ...
来源:[J].Breast Cancer Research(IF 5.872), 2017, Vol.19 (1)Springer
摘要:... We focused on one of the most aggressive circulating tumor cells (CTCs) which, from the primitive tumor, spreads to the central nervous system (CNS), evaluating the expression of prognostic and putative cancer stem cell markers in breast cancer (BC) leptomeningeal metastasis ...
作者:Yanfang Ju , Jinliang Wang , Shengjie Sun ...
来源:[J].Journal of Cancer Research and Therapeutics(IF 0.761), 2016, Vol.12 (7), pp.181-185Wolters Kluwer
摘要:Objective: Leptomeningeal metastasis (LM) leades a devastating consequence in patients with nonsmall cell lung cancer(NSCLC). Treatment is very limited for patients with LM. We introduced to use nimotuzumab (also known as h-R3) combined with methotrexate for treating LM in NS...
作者:Anna Niwińska , Halina Rudnicka , Magdalena Murawska
来源:[J].Clinical Breast Cancer(IF 2.422), 2015, Vol.15 (1), pp.66-72Elsevier
摘要:Abstract(#br)Background(#br)This was a prospective observational study to assess the results of the treatment of patients with breast cancer leptomeningeal metastasis (LM) and to compare the efficacy of methotrexate and liposomal cytarabine in patients treated intrathecally by lu...
作者:Adrienne Boire , Yilong Zou , Jason Shieh ...
来源:[J].Cell(IF 31.957), 2017, Vol.168 (6), pp.1101-1113.e13Elsevier
摘要:Summary(#br)We molecularly dissected leptomeningeal metastasis, or spread of cancer to the cerebrospinal fluid (CSF), which is a frequent and fatal condition mediated by unknown mechanisms. We selected lung and breast cancer cell lines for the ability to infiltrate and grow in CS...
作者:Jin Sun Lee , Michelle E. Melisko , Mark Jesus M. Magbanua ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2015, Vol.154 (2), pp.339-349Springer
摘要:... We tested the feasibility of tumor cell detection in the cerebrospinal fluid (CSF) and studied its clinical relevance in leptomeningeal metastasis (LM) of breast cancer. CSF samples were collected from 38 metastatic breast cancer patients known or suspected to have LM. C...
作者:Masafumi Toyoshima , Keita Tsuji , Shogo Shigeta ...
来源:[J].Clinical Imaging(IF 0.648), 2017, Vol.41, pp.42-47Elsevier
摘要:Abstract(#br)Leptomeningeal metastasis (LM) is rarely observed in gynecologic cancers. As gadolinium-enhanced magnetic resonance imaging (Gd-MRI) is highly effective for diagnosing LM, the aim of this study is to describe the clinical behaviors and outcomes of LM patients who wer...

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