全部文献期刊会议图书|学者科研项目
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作者:Antonio Ceriello , Harold W. deValk , Bruno Guerci ...
来源:[J].Diabetes Research and Clinical Practice(IF 2.741), 2020, Vol.161
摘要:Abstract(#br)Due to the progressive nature of type 2 diabetes (T2DM), initiation of insulin therapy is very likely in the disease continuum. This article aims at highlighting the current situation with regard to insulin therapy in people with T2DM in Europe and at presenting the ...
作者:Kana N. Miyata , Shuiling Zhao , Chin-Han Wu ...
来源:[J].Diabetes Research and Clinical Practice(IF 2.741), 2020
摘要:Abstract(#br)Aims(#br)SGLT2 inhibitors have been proposed as an adjunct to insulin therapy for glycemic control in type 1 diabetes (T1D) patients. However, concern has been raised due to an increase in renin–angiotensin-system (RAS) activity reported in a clinical trial in whi...
作者:Ansab Akhtar , Sangeeta Pilkhwal Sah
来源:[J].Neurochemistry International(IF 2.659), 2020, Vol.135
摘要:... Its major pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from dysfunctional insulin signaling. Insulin is an important growth factor that regulates cell growth, energy utilization, mitochondrial function, autophagy, oxidative stress...
作者:Sunil Kumar Dubey , K.K. Lakshmi , Kowthavarapu Venkata Krishna ...
来源:[J].Life Sciences(IF 2.555), 2020, Vol.249
摘要:... Together, impaired insulin signaling in the brain is also observed as essential factor to be considered in AD pathophysiology. Hence, currently researchers focused on studying the effect of brain insulin metabolism and relation of diabetes with AD. Based on the investigations...
作者:Sandeep Das , Dipayan Choudhuri
来源:[J].Life Sciences(IF 2.555), 2020
摘要:Abstract(#br)Aims(#br)Dietary calcium a common nutrient of our daily diet found to have an anti-obesity effect which may also regulate insulin sensitivity but this effect and the exact mechanism remains unexplored. Therefore, we aimed to study the effect of different types of ...
作者:V.M. Paes , L.F. Lima , A.C.A. Ferreira ...
来源:[J].Theriogenology(IF 2.082), 2020, Vol.147, pp.10-17
摘要:... Here we investigated the in vitro effects of thyroxine combined with insulin on caprine preantral follicle survival and development. Sliced ovarian tissues were cultured for 1 or 7 days using 10 ng/mL (low) or 10 μg/mL (high) insulin in the presence of thyroxine at 0, 0.5,...
作者:Xiangdong Wu , Keyang Chen , Kevin Jon Williams
来源:[J].Atherosclerosis(IF 3.706), 2020, Vol.298, pp.42-51
摘要:... These features share an unexplained origin – namely, imbalanced insulin action, also called pathway-selective insulin resistance and responsiveness. To control glycemia, these patients require hyperinsulinemia that then overdrives ERK and hepatic de-novo lipogenesis. We p...
作者:Ilia Ostrovski , Leif E. Lovblom , Daniel Scarr ...
来源:[J].Canadian Journal of Diabetes(IF 0.458), 2020, Vol.44 (3), pp.229-235
摘要:Abstract(#br)Objectives(#br)To better understand the dawn phenomenon in type 1 diabetes, we sought to determine its prevalence, timing and magnitude in studies specifically designed to assess basal insulin requirements in patients using insulin pumps.(#br)Methods(#br)Thirty-thre...
作者:Pouneh Sadat Pourhosseini , Reza Amani , Ali Akbar Saboury ...
来源:[J].Journal of the Iranian Chemical Society(IF 1.467), 2017, Vol.14 (12), pp.2637-2648Springer
摘要:... In vitro release behavior of bovine insulin from LA37–EG136–LA37 micelles is evaluated at 37 °C. According to results, nearly 90 wt% of insulin is released over 6 days by diffusion in a biphasic pattern. Secondly, a comparative study...
作者:Juan Li , Ernest Hung Yu Ng , Elisabet Stener-Victorin ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:Our prospective pilot study of acupuncture affecting insulin sensitivity on polycystic ovary syndrome (PCOS) combined with insulin resistance (IR) showed that acupuncture had a significant effect on improving the insulin sensitivity of PCOS. But there is still no randomized contr...

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