全部文献期刊会议图书|学者科研项目
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作者:Dongfang Liu , Shuo Tian , Kai Zhang ...
来源:[J].Protein & Cell(IF 3.22), 2017, Vol.8 (12), pp.861-877
摘要:... Current chimeric antigen receptor (CAR)-modified T cell immunotherapy shows strong promise for treating various cancers and infectious diseases. Although CAR-modified NK cell immunotherapy is rapidly gaining attention, its clinical applications are mainly focused on precli...
作者:Giovanni Battista Pajno , Roberto Bernardini , Diego Peroni ...
来源:[J].Italian Journal of Pediatrics, 2017, Vol.43 (1)
摘要:Allergen-specific immunotherapy (AIT) is currently recognized as a clinically effective treatment for allergic diseases, with a unique disease-modifying effect. AIT was introduced in clinical practice one century ago, and performed in the early years with allergenic extracts of p...
作者:Giorgio Ciprandi , Valentina Natoli , Paola Puccinelli ...
来源:[J].Allergy, Asthma & Clinical Immunology, 2017, Vol.13 (1)
摘要:As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House dust mite (HDM) allergy is very common. The aim of the current experi...
作者:Hwei-Fang Tsai , Ping-Ning Hsu
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)
摘要:... These immune checkpoint blocking antibodies have moved immunotherapy into a new era, and they represent paradigm-shifting therapeutic strategies for cancer treatment. A clearer understanding of the regulatory roles of these receptors and elucidation of the mechanisms of T ...
作者:María Morales , Mayte Gallego , Victor Iraola ...
来源:[J].BMC Immunology(IF 2.61), 2017, Vol.18 (1)
摘要:... Allergen specific immunotherapy is therefore recommended for these patients. The use of polymerized allergen extracts, allergoids, would allow to achieve the high allergen doses suggested to be effective while maintaining safety.
作者:Jordi Remon , Benjamin Besse , Jean-Charles Soria
来源:[J].BMC Medicine(IF 6.679), 2017, Vol.15 (1)
摘要:Immune checkpoint inhibitors have significantly modified the therapeutic landscape of advanced non-small cell lung cancer in second-line settings, with a more recent advancement in first-line settings. Given the superior outcome with pembrolizumab as an upfront strategy, PD-L1 st...
作者:Sandra Andorf , Monali Manohar , Tina Dominguez ...
来源:[J].Allergy, Asthma & Clinical Immunology, 2017, Vol.13 (1)
摘要:Clinical trials using oral immunotherapy (OIT) for the treatment of food allergies have shown promising results. We previously demonstrated the feasibility of desensitization for up to 5 food allergens simultaneously through OIT. In this observational study, we report the finding...
作者:L. M. A. Aparicio , I. P. Fernandez , J. Cassinello
来源:[J].Clinical and Translational Oncology(IF 1.276), 2017, Vol.19 (10), pp.1175-1182
摘要:... The confirmation that TKIs improve cell cytokine response in mRCC provides a basis for the rational combination and sequential treatment of TKIs and immunotherapy.
作者:Petr Szturz , Jan B. Vermorken
来源:[J].BMC Medicine(IF 6.679), 2017, Vol.15 (1)
摘要:... Immunotherapy is based on functional restoration of the host immune system, helping to counteract various tumour evasion strategies. Broadly, immunotherapeutic approaches encompass tumour-specific antibodies, cancer vaccines, cytokines, adoptive T-cell transfer, and immune-mo...
作者:Francesca Finotello , Zlatko Trajanoski
来源:[J].Genome Medicine(IF 3.397), 2017, Vol.9 (1)
摘要:... Two recent studies report distinct transcriptional profiles of tumor-infiltrating Treg cells and expression of specific molecules, suggesting novel strategies to overcome resistance to cancer immunotherapy.

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