全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Clara Crescioli , Mariangela Sottili , Paolo Bonini ...
来源:[J].European Journal of Cell Biology(IF 3.213), 2011, Vol.91 (2), pp.139-149
摘要:Abstract(#br)Inflammatory myopathies (IMs) are systemic diseases characterized by a T helper (Th) 1 type inflammatory response and cell infiltrates within skeletal muscles. The mainstay of treatment is drugs aimed at suppressing the immune system – corticosteroids and immunos...
作者:Cristina Antinozzi , Clarissa Corinaldesi , Carla Giordano ...
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2017, Vol.167, pp.169-181
摘要:Abstract(#br)Vitamin D plays a pivotal role to maintain skeletal muscle integrity and health. Vitamin D deficiency characterizes inflammatory myopathy (IM) and diabetes, often overlapping diseases involving skeletal muscle damage. Vitamin D receptor (VDR) agonists likely exert be...
作者:Christopher May , Lukas Weigl , Anton Karel ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2006, Vol.71 (10), pp.1497-1509
摘要:... The sequential expression of P2X and P2Y receptors has been correlated to these effects in many species and cell lines. We have therefore investigated ATP mediated signalling in differentiated primary human skeletal muscle cells. ATP was capable to trigger Ca 2+ transients...
作者:Christian Klingler , Xinjie Zhao , Till Adhikary ...
来源:[J].BBA - Molecular and Cell Biology of Lipids(IF 4.134), 2016, Vol.1861 (12), pp.1980-1992
摘要:Abstract(#br)Metabolomics studies of human plasma demonstrate a correlation of lower plasma lysophosphatidylcholines (LPC) concentrations with insulin resistance, obesity, and inflammation. This relationship is not unraveled on a molecular level. Here we investigated the effec...
作者:Nils G. Løvsletten , Helene Vu , Christine Skagen ...
来源:[J].Scientific Reports(IF 2.927), 2020, Vol.10 (1), pp.883-891
摘要:... Despite catalysing the same reaction and being present in the same cell types, they exhibit different functions on lipid metabolism in various tissues. Yet, their roles in skeletal muscle remain poorly defined. In this study, we investigated how selective inhibitors of DG...
作者:Ad A.G.M. Benders , Arie Oosterhof , Ron A. Wevers ...
来源:[J].Cell Calcium(IF 4.327), 1997, Vol.21 (1), pp.81-91
摘要:Abstract(#br)Cultured human skeletal muscle cells are frequently used as a model to study muscle pathology, in which Ca 2+ homeostasis might be affected. However, their excitation-contraction (E-C) coupling has been poorly investigated.(#br)In order to elucidate E-C coupling ...
作者:Gabriella Czifra , István Balázs Tóth , Rita Marincsák ...
来源:[J].Cellular Signalling(IF 4.304), 2005, Vol.18 (9), pp.1461-1472
摘要:Abstract(#br)In this study, we have investigated the effects of insulin-like growth factor-I (IGF-I) on cellular responses of primary human skeletal muscle cells and mouse C2C12 myoblasts. In human muscle, IGF-I stimulated proliferation and fusion of the cells and the expres...
作者:Ine Blankenberg Skottheim , Ane Gedde-Dahl , Solmaz Hejazifar ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2007, Vol.33 (4), pp.317-325
摘要:... Primary human skeletal muscle cells were incubated with increasing concentrations of lactone and acid forms of atorvastatin, fluvastatin, pravastatin and simvastatin. Following incubation, living myotubes were quantified by fluorescence staining. Atorvastatin lactone showed a...
作者:Audrey E. Brown , Stephen J. Yeaman , Mark Walker
来源:[J].Molecular Genetics and Metabolism(IF 2.834), 2007, Vol.91 (4), pp.318-324
摘要:... As skeletal muscle is the principal site of the peripheral insulin resistance for glucose disposal in type 2 diabetes, we investigated whether targeted suppression of calpain-10 expression directly affects insulin action in cultured human skeletal muscle cells. Short interfe...
作者:F. Marampon , C. Antinozzi , C. Corinaldesi ...
来源:[J].Endocrine(IF 2.25), 2018, Vol.59 (3), pp.602-613
摘要:... We have previously reported that tadalafil targets human skeletal muscle cells with an insulin (I)-like effect. We aim to evaluate in human fetal skeletal muscle cells after tadalafil or I: (i) expression profile of I-regulated genes dedicated to cellular energy control, ...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×