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作者:M. Hermann , R. Margreiter , P. Hengster
来源:[J].Journal of Cellular and Molecular Medicine(IF 4.753), 2007, Vol.11 (3), pp.398-415Wiley
摘要: • Introduction(#br)Human islet transplantation(#br)In search of an “endless pool” of β‐cells: embryonic stem cells, adult mesenchymal stem cells, progenitor cells, cell lines and xenotransplantations(#br)•cell proliferati...
作者:Vaibhav Mundra , Hao Wu , Ram I Mahato
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (10)DOAJ
摘要:The objective of this study was to determine the potential of human bone marrow derived mesenchymal stem cells (hBMSCs) as gene carriers for improving the outcome of human islet transplantation. hBMSCs were characterized for the expression of phenotypic markers and transduced wit...
作者:Sandra Marín-Cañas , Elisabet Estil Les , Laura Llado ...
来源:[J].PLoS ONE(IF 3.73), 2019, Vol.14 (7)DOAJ
摘要:AIM:To evaluate the effect of pancreatic ductal cells on experimental human islet transplantation. MATERIALS AND METHODS:Isolated islets were additionally purified by handpicking. Ductal cells were purified by magnetic cell sorting and then clustered into ductal pancreatosphe...
作者:Elisabet Estil·les , Noèlia Téllez , Montserrat Nacher ...
来源:[J].Cell Transplantation(IF 4.422), 2018, Vol.27DOAJ
摘要:... The sensitivity of beta cells to STZ is species-specific and human beta cells are resistant to STZ. In experimental islet transplantation to rodents, STZ-diabetes must be induced before transplantation to avoid destruction of grafted islets by STZ. In human islet transplantation...
作者:Elisabet Estil·les , Noèlia Téllez , Montserrat Nacher ...
来源:[J].Cell Transplantation(IF 4.422), 2018, Vol.27 (11), pp.1684-1691Sage国际出版集团
摘要:... The sensitivity of beta cells to STZ is species-specific and human beta cells are resistant to STZ. In experimental islet transplantation to rodents, STZ-diabetes must be induced before transplantation to avoid destruction of grafted islets by STZ. In human islet transplantation...
作者:José Caballero-Corbalán , Heide Brandhorst , Helene Malm ...
来源:[J].Journal of Surgical Research(IF 2.018), 2012, Vol.175 (1), pp.163-168Elsevier
摘要:... In human islet transplantation, HTK provided similar isolation outcomes after short CIT. The present study aimed to investigate whether islets can be successfully isolated from HTK-preserved pancreata after prolonged CIT compared with UWS.(#br)Materials and Methods(#br)Si...
作者:P. Y. Benhamou , J. Oberholzer , C. Toso ...
来源:[J].Diabetologia(IF 6.487), 2001, Vol.44 (7), pp.859-864Springer
摘要:... Improvements in islet transplantation require clinical series large enough to implement controlled new strategies. The goal of this study was to demonstrate the feasibility of a multicentre network for islet transplantation in Type I (insulin-dependent) diabetic patients. ...
作者:Yong Wang , Meirigeng Qi , James J. McGarrigle ...
来源:[J].Current Diabetes Reports(IF 3.165), 2013, Vol.13 (5), pp.723-732Springer
摘要:Abstract(#br)Human islet transplantation is an effective and promising therapy for type I diabetes. However, long-term insulin independence is both difficult to achieve and inconsistent. De novo or early administration of incretin-based drugs is being explored for improving islet...
作者:Romie F. Gibly , Xiaomin Zhang , William L. Lowe ...
来源:[J].Cell Transplantation(IF 4.422), 2013, Vol.22DOAJ
摘要:Islet transplantation as a therapy or cure for type 1 diabetes has significant promise but has been limited by islet mass requirements and long-term graft failure. The intrahepatic and intravascular site may be responsible for significant loss of transplanted islets. Nonencapsula...
作者:Babak Movahedi , Bart Keymeulen , Mary-Helen Lauwers ...
来源:[J].Transplant International(IF 3.155), 2003, Vol.16 (3), pp.186-190Springer
摘要:Intra-portal islet transplantation is usually performed by cannulation of a mesenteric vein during laparotomy or through percutaneous trans-hepatic cannulation of a portal branch. In this study, we describe a new laparoscopic technique for intra-portal islet transplantation in a ...

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