全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Constantinos Giaginis , Anastasia Sampani , Iolly Kotta-Loizou ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2018, Vol.24 (3), pp.631-640
摘要:Abstract(#br)Hu-antigen R (HuR), a RNA-binding protein, is considered to play a crucial role in tumor development and progression by stabilizing or regulating a group of cellular mRNAs of cancer-related genes, such as cyclooxygenase-2 (COX-2). The present study aimed to eval...
作者:Toyota Kazuhiro , Murakami Yoshiaki , Kondo Naru ...
来源:[J].Annals of surgical oncology, 2018, Vol.25 (5), pp.1202-1210
摘要:BACKGROUND(#br)Hu-antigen R (HuR) is an RNA-binding protein that regulates the stability, translation, and nucleus-to-cytoplasm translocation of messenger RNAs (mRNAs).(#br)OBJECTIVE(#br)The aim of this study was to investigate the prognostic significance of HuR in cholangiocarci...
作者:Mingxia Wu , Christy W.S. Tong , Wei Yan ...
来源:[J].Current Cancer Drug Targets(IF 4), 2019, Vol.19 (5), pp.382-399
摘要:... Human antigen R (HuR) is an RNA-binding protein that regulates thestability, translation, and nucleus-to-cytoplasm shuttling of its target mRNAs. While HuR is normallylocalized within the nucleus, it has been shown that HuR binds mRNAs in the nucleus andthen escorts the mRNA...
作者:Mingxia Wu , Christy W.S. Tong , Wei Yan ...
来源:[J].Current Cancer Drug Targets(IF 4), 2019, Vol.19 (5), pp.382-399
摘要:... Human antigen R (HuR) is an RNA-binding protein that regulates the stability, translation, and nucleus-to-cytoplasm shuttling of its target mRNAs. While HuR is normally localized within the nucleus, it has been shown that HuR binds mRNAs in the nucleus and then escorts the m...
作者:Constantinos Giaginis , Paraskevi Alexandrou , Ioanna Delladetsima ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2016, Vol.22 (1), pp.189-196
摘要:Abstract(#br)Hu-antigen R (HuR) is considered to play a crucial role in tumor formation and growth by binding to mRNAs encoding proteins such as Cyclooxygenase-2 (COX-2) and inducing their expression via mRNA stabilization and/or altered translation. The present study aimed ...
作者:Amadio M , Osera C , Lupo G ...
来源:[J].Molecular vision(IF 1.987), 2012, Vol.18, pp.2153-64
摘要:PURPOSE(#br)To explore whether, following direct contact, there is mutual influence between pericytes (PC) and endothelial cells (EC), and to establish whether protein kinase C (PKC) activation, a condition associated with hyperglycemia, can affect, via the mRNA-binding Hu-antigen...
作者:W. Arnout van Hattem , Lodewijk A.A. Brosens , Susan Y. Marks ...
来源:[J].Clinical Gastroenterology and Hepatology(IF 6.648), 2008, Vol.7 (1), pp.93-97
摘要:... Two additional markers, Hu-antigen R, a stabilizer of messenger RNA, and CCAAT/enhancer-binding protein β, a transcription factor, both associated with increased COX-2 expression, also were investigated.(#br)Results(#br)Increased COX-2 expression in JPS patients was note...
作者:Giaginis Constantinos , Sampani Anastasia , Kotta-Loizou Iolly ...
来源:[J].Pathology oncology research : POR, 2018, Vol.24 (3), pp.631-640
摘要:Hu-antigen R (HuR), a RNA-binding protein, is considered to play a crucial role in tumor development and progression by stabilizing or regulating a group of cellular mRNAs of cancer-related genes, such as cyclooxygenase-2 (COX-2). The present study aimed to evaluate the clinical ...
作者:Wu Mingxia , Tong Christy W S , Yan Wei ...
来源:[J].Current cancer drug targets, 2018
摘要:... Human antigen R (HuR) is a RNA-binding protein that regulates the stability, translation, and nucleus-to-cytoplasm shuttling of its target mRNAs. While HuR is normally localized within the nucleus, it has been shown that HuR binds mRNAs in the nucleus and then escorts the mRN...
作者:Ioly Kotta-Loizou , Spyridon N. Vasilopoulos , Robert H.A. Coutts ...
来源:[J].Neoplasia, 2016, Vol.18 (11), pp.674-688
摘要:Abstract(#br)Hu-antigen R (HuR) is an RNA-binding posttranscriptional regulator that belongs to the Hu/ELAV family. HuR expression levels are modulated by a variety of proteins, microRNAs, chemical compounds, or the microenvironment, and in turn, HuR affects mRNA stability and tr...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×