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作者:Mitali Mishra , Seetaram Mohapatra , Nilima Priyadarsini Mishra ...
来源:[J].Tetrahedron Letters(IF 2.397), 2019, Vol.60 (33)
摘要:Abstract(#br)Heterocyclic compounds particularly five, six and seven membered ring containing heterocycles are the most abundant which constitute a staggeringly diverse and important class of molecules that occur ubiquitously in a variety of synthetic drugs, bioactive natural...
作者:Leon Jacobs , Carmen de Kock , Dale Taylor ...
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2018
摘要:... We synthesized five libraries of 6,5-fused heterocycles to establish the importance of the heterocycles as core scaffolds, as well as introduced various aromatic amides and esters to determine which carbonylic group affects the potency of each heterocyclic antiplasmodial agen...
作者:Sumana Y. Kotian , Chakrabhavi Dhananjaya Mohan , Aloir A. Merlo ...
来源:[J].Journal of Molecular Liquids(IF 1.684), 2019
摘要:... The research in the past few decades shows the substantial increase in the exploring of applications of five-membered liquid crystalline heterocycles in photovoltaic devices, organic light-emitting technologies, and biological systems. In this article, we have discussed the h...
作者:Navjeet Kaur
来源:[J].Inorganic Chemistry Communications(IF 2.016), 2018, Vol.99, pp.82-107
摘要:Abstract(#br)Nitrogen, oxygen, and sulfur containing heterocycles have a wide range of biological activities. Metal catalysts are used in organic reactions with high activity. New strategies have been developed for the preparation of heterocycles in the last decades. The meta...
作者:Bubun Banerjee
来源:[J].Ultrasonics - Sonochemistry(IF 3.516), 2017, Vol.35, pp.15-35
摘要:Abstract(#br)Heterocycles are the backbone of organic compounds. Specially, N - & O -containing heterocycles represent privileged structural subunits well distributed in naturally occurring compounds with immense biological activities. Multicomponent reactions (MCRs) are becomi...
作者:Imran Ali , Mohammad Nadeem Lone , Zeid A. Alothman ...
来源:[J].Journal of Molecular Liquids(IF 1.684), 2017, Vol.234, pp.391-402
摘要:Abstract(#br)In quest to develop effective anticancer drugs, a series of twelve heterocycles ( 1 − 12 ) embedded with oxopyrrolidine rings was synthesized. The compounds ( 1 – 12 ) were characterized by microanalysis, FT-IR, UV–Vis and 1 H NMR spectroscopy, and mass spe...
作者:Matthew S. Ward , Isba Silva , Walfre Martinez ...
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2016, Vol.24 (15), pp.3267-3275
摘要:... Five known antibiotics/inhibitors and 28 boron heterocycles were tested by TIPA II assay, in conjunction with the original assay TIPA. The TIPA II was more sensitive than TIPA because eight boron heterocycles previously found to be inactive to AG1 cells in TIPA assays exhibit...
作者:Christopher T. Walsh
来源:[J].Tetrahedron Letters(IF 2.397), 2015, Vol.56 (23), pp.3075-3081
摘要:Abstract(#br)Nitrogen-containing heterocycles are central to the chemical reactions that occur in all organisms. The metabolic transformation of amino acids into five, six, and seven-member heterocycles reveals the chemical logic and enzymatic machinery for shunting primary metab...
作者:Harjeet S. Soor , Solomon D. Appavoo , Andrei K. Yudin
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2018, Vol.26 (10), pp.2774-2779
摘要:... In this mini-review we discuss key examples in which heterocycles influence the conformational stability and other properties of macrocycles.
作者:Gregory Landelle , Etienne Schmitt , Armen Panossian ...
来源:[J].Journal of Fluorine Chemistry(IF 1.939), 2017, Vol.203, pp.155-165
摘要:... To allow a facile access to the second F 2 HCO-containing key intermediate, the difluoromethylation of hydroxylated N -based heterocycles has been developed using difluoromethyl triflate (a liquid non-ODS reagent) under air in aqueous conditions and with very short reacti...

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