全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Robert Galinsky , Joanne O Davidson , Justin M Dean ...
来源:[J].Neural Regeneration Research(IF 0.144), 2018, Vol.13 (2), pp.181-189DOAJ
摘要:... In this review, we discuss the role of astrocytic gap junction (connexin) hemichannels in the spread of neural injury after hypoxia-ischemia and/or infection/inflammation. Potential mechanisms of hemichannel mediated injury likely involve impaired intracellular calcium handli...
作者:Viviana M. Berthoud , Anaclet Ngezahayo
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:... Congenital cataract-associated connexin mutants can affect protein trafficking, stability and/or function, and the functional effects may differ between gap junction channels and hemichannels. Dominantly inherited cataracts may result from effects of the connexin mutant on it...
作者:Andrei B. Belousov , Joseph D. Fontes , Moises Freitas-Andrade ...
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:... These channels are composed of connexin proteins that oligomerize into hexamers to form connexons or hemichannels. Many different connexins are expressed in the CNS, with some specificity with regard to the cell types in which distinct connexins are found, as well as the time...
作者:F. Villanelo , Y. Escalona , C. Pareja-Barrueto ...
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. These channels allow intercellular transfer of molecules up to ~1 kDa, including water, ions and other metabolites. Unveiling structure-function relationships coded into the mole...
作者:Thomas Desplantez
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:This review comes after the International Gap Junction Conference (IGJC 2015) and describes the current knowledge on the function of the specific motifs of connexins in the regulation of the formation of gap junction channels. Moreover the review is complemented by a summarized d...
作者:Kristin Pogoda , Petra Kameritsch , Mauricio A. Retamal ...
来源:[J].BMC Cell Biology(IF 2.808), 2016, Vol.17 (1)Springer
摘要:... The prerequisite for the formation of functional gap junction channels is the assembly of connexin proteins into hemichannels and their insertion into the membrane. Hemichannels can affect cellular processes by enabling the passage of signaling molecules between the intracell...
作者:Brian Skriver Nielsen , Daniel Bloch Hansen , Bruce R. Ransom ...
来源:[J].Neurochemical Research(IF 2.125), 2017, Vol.42 (9), pp.2537-2550Springer
摘要:... These proteins may exist as hemichannels in the plasma membrane in the absence of a ‘docked’ counterpart on the neighboring cell. A variety of stimuli are reported to open the hemichannels and thereby create a permeation pathway through the plasma membrane. Cx30 and C...
作者:Vytas K. Verselis
来源:[J].Neuroscience Letters(IF 2.026), 2019, Vol.695, pp.40-45Elsevier
摘要:... Connexins function as gap junction channels and as hemichannels, which mediate intercellular and transmembrane signaling, respectively. Both channel configurations can play important, but very different roles in the cochlea. The potential roles connexin hemichannels can play ...
作者:Ashish Kumar Gadicherla , Nan Wang , Marco Bulic ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2017, Vol.112 (3)Springer
摘要:... Cx43 also forms calcium (Ca2+)-permeable hemichannels that may potentially lead to mitochondrial Ca2+ overload and cell death. Here, we studied the role of Cx43 in facilitating mitochondrial Ca2+ entry and investigated its downstream consequ...
作者:Mohammad Shahidullah , Nicholas A. Delamere
来源:[J].Experimental Eye Research(IF 3.026), 2014, Vol.118, pp.20-29Elsevier
摘要:Abstract(#br)The expression of connexins in the ciliary epithelium is consistent with gap junctions between the pigmented (PE) and nonpigmented ciliary epithelium (NPE) that form when connexon hemichannels from adjacent cells pair to form a channel. Here we present evidence ...

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