全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Fei-hu Zhang , Yu-han Sun , Kai-liang Fan ...
来源:[J].BMC Gastroenterology(IF 2.11), 2017, Vol.17 (1)Springer
摘要:Heme oxygenase-1 (HO-1) is an inducible defense gene which plays a significant role in inflammation. HO-1 protects cells and tissues through the mechanism of anti-oxidation, maintaining microcirculation and anti-inflammation. The aim of the current study is to investigate the rol...
作者:Xi Qiao , Lihua Wang , Yanhong Wang ...
来源:[J].BMC Nephrology(IF 1.644), 2017, Vol.18 (1)Springer
摘要:... Heme oxygenase-1 (HO-1), an antioxidant agent, is associated with antifibrogenic effects. ADM is known to induce HO-1. Whether IMD has any effect on HO-1 is unclear. Herein, we determined whether the antifibrotic properties of IMD are mediated by induction of HO-1.
作者:Xiaobo Yang , Hong Jiang , Yao Shi
来源:[J].Cell & Bioscience(IF 3), 2017, Vol.7 (1)Springer
摘要:Curcumin is a major constituent of rhizomes of Curcuma longa that elicits beneficial effects for oxidative damage. The aim of this study was to investigate whether curcumin could attenuate hydrogen peroxide (H2O2)-induced apoptosis in H9c2 cardiomyoblasts an...
作者:Sang Jae Noh , Kyoung Min Kim , Kyu Yun Jang
来源:[J].Diagnostic Pathology(IF 1.85), 2017, Vol.12 (1)Springer
摘要:... Recently, it has been suggested that NGF induces heme oxygenase-1 (HO1) expression, and that both NGF and HO1 are involved in the progression of malignant human tumors. However, exact roles of NGF and HO1 in tumorigenesis remain controversial. Therefore, we investigated the e...
作者:Su-Jin Moon , Eun-Kyung Kim , Joo Yeon Jhun ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2017, Vol.15 (1)Springer
摘要:Leflunomide is a low-molecular-weight compound that is widely used in the treatment of rheumatoid arthritis. Although leflunomide is thought to act through the inhibition of the de novo pyrimidine synthesis, the molecular mechanism of the drug remains largely unknown. We investig...
作者:Zhang JQ , Zhang JQ , Fang LZ ...
来源:[J].Drug Design, Development and Therapy(IF 3.486), 2015, Vol.2015 (Issue 1), pp.6379-6387DOAJ
摘要:Jia-Qiang Zhang, Jian-Qing Zhang, Li-Zhou Fang, Ling Liu, Wei-Ping Fu, Lu-Ming DaiThe Second Department of Respiratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, People’s Republic of ChinaBackground: Heme oxygenase-1 (HO-1) plays a prot...
作者:Luana M. Manosso , Morgana Moretti , Julia M. Rosa ...
来源:[J].Pharmacological Reports(IF 1.965), 2017, Vol.69 (3), pp.497-503Elsevier
摘要:Abstract(#br)Background(#br)Considering that heme oxygenase-1 (HO-1) and the brain-derived neurotrophic factor (BDNF)-mediated pathway are involved in the pathophysiology of depression and that zinc has been shown to exert beneficial effects in the management of depression, t...
作者:Si Chao Yan , Ya Jie Wang , Yu Jie Li ...
来源:[J].Molecules(IF 2.428), 2019, Vol.24 (13)DOAJ
摘要:... Moreover, it promoted heme oxygenase-1 (HO-1) production in vitro and in vivo, concomitant with CD4+ T cell apoptosis and restoration of the Th/Treg balance, and these effects were blocked by treatment with the HO-1 inhibitor Sn-protoporphyrin IX. Overall, these results sugge...
作者:Valeria Sorrenti , Marco Raffaele , Luca Vanella ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2019, Vol.20 (10)DOAJ
摘要:... The aim of the present study was to investigate if the potentially protective effects of phenethyl ester of caffeic acid (CAPE), a natural phenolic compound occurring in a variety of plants and derived from honeybee hive propolis, and of a novel CAPE analogue, as heme oxygenase-1...
作者:In-Hyoung Yang , Chi-Hyun Ahn , Nam-Pyo Cho ...
来源:[J].Molecules(IF 2.428), 2019, Vol.24 (9)DOAJ
摘要:... Proteome profiling using a human apoptosis array revealed four candidate proteins and of these, heme oxygenase-1 (HO-1) was mainly related to the differential response to TW-37 of YD-15 and MC3 cells. TW-37 also led to a significant increase in intracellular levels of ROS...

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