全部文献期刊会议图书|学者科研项目
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作者:Lydia G. Roos , Johanna Janson , Sarah C. Sturmbauer ...
来源:[J].Psychoneuroendocrinology(IF 5.137), 2018
摘要:... however, failure of the hypothalamic-pituitary-adrenal (HPA) axis to habituate (i.e., nonhabituation) involves continuing to become highly activated in response to repeated exposure of the same stimulus and is considered maladaptive. Although 50-75% of individuals assessed in...
作者:Laverne Camille Melón , Andrew Hooper , Xuzhong Yang ...
来源:[J].Psychoneuroendocrinology(IF 5.137), 2018, Vol.90, pp.182-193
摘要:Abstract(#br)The stress-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis is normally suppressed during pregnancy. Dysregulation of the HPA axis has been proposed to play a role in postpartum depression. However, direct investigation into the relationship bet...
作者:Andrew Hooper , Rumzah Paracha , Jamie Maguire
来源:[J].Epilepsy & Behavior(IF 1.844), 2018, Vol.78, pp.124-133
摘要:Abstract(#br)Our laboratory recently demonstrated that seizures activate the hypothalamic-pituitary-adrenal (HPA) axis, increasing circulating levels of corticosterone (O'Toole et al., 2013). Given the well-established proconvulsant actions of corticosterone, we hypothesized th...
作者:Xiao-Jie Zhao , Zhan Zhao , Dan-Dan Yang ...
来源:[J].Brain Research Bulletin(IF 2.935), 2017, Vol.130, pp.146-155
摘要:Abstract(#br)Stress-induced disturbance of the hypothalamic-pituitary-adrenal (HPA) axis is strongly implicated in incidence of mood disorders. A heightened neuroinflammatory response and oxidative stress play a fundamental role in the dysfunction of the HPA axis. We have previ...
作者:Robert L Spencer , Terrence Deak
来源:[J].Physiology & Behavior(IF 3.16), 2016
摘要:Abstract(#br)Glucocorticoid hormones (cortisol and corticosterone - CORT) are the effector hormones of the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic intercellular signal whose level predictably varies with time of day and dynamically incr...
作者:Carolina de Weerth
来源:[J].Neuroscience and Biobehavioral Reviews(IF 9.44), 2017, Vol.83, pp.458-471
摘要:... The Hypothalamic-Pituitary-Adrenal axis (HPA axis) is a major physiological stress system that produces cortisol. This hormone is involved in responding to environmental stress and also shapes many aspects of brain development. Both the HPA axis and the intestinal microbiota ...
作者:Mohammad Hossein Esmaeili , Behnam Bahari , Ali-Akbar Salari
来源:[J].Brain Research Bulletin(IF 2.935), 2018, Vol.137, pp.265-276
摘要:... Dysregulation of the hypothalamic-pituitary-adrenal-(HPA) axis has been reported in affective disorders and AD. Recent studies revealed that current antidepressant drugs are not completely effective for treating anxiety- and depression-related disorders in people with dem...
作者:Kirsten Cherian , Alan F. Schatzberg , Jennifer Keller
来源:[J].Schizophrenia Research(IF 4.59), 2019, Vol.213, pp.72-79
摘要:Abstract(#br)The Hypothalamic Pituitary Adrenal (HPA) axis has been implicated in the pathophysiology of a variety of mood and cognitive disorders. Neuroendocrine studies have demonstrated HPA axis overactivity in major depression, a relationship of HPA axis activity to cognitive...
作者:Bruno Agustini , Mariia Bocharova , Adam J. Walker ...
来源:[J].Journal of Affective Disorders(IF 3.295), 2019, Vol.256, pp.584-593
摘要:... However, there are no systematic reviews on SAD and Hypothalamic-Pituitary-Adrenal (HPA) axis function. This review intends to summarize these findings.(#br)Methods(#br)Using the PRISMA (2009) guideline recommendations we searched for relevant articles indexed in databases...
作者:Nathan K. Evanson , James P. Herman
来源:[J].Physiology & Behavior(IF 3.16), 2015, Vol.150, pp.2-7
摘要:Abstract(#br)Glutamate is an important neurotransmitter in the regulation of the neural portion of hypothalamus–pituitary–adrenal (HPA) axis activity, and signals through ionotropic and metabotropic receptors. In the current studies we investigated the role of hypothalamic p...

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