全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Soichiro Ide , Yuiko Ikekubo , Masayoshi Mishina ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2017, Vol.135 (3), pp.138-140DOAJ
摘要:We investigated the rapid and sustained antidepressant effects of enantiomers of ketamine in N-methyl-d-aspartate (NMDA) receptor GluN2D subunit knockout (GluN2D-KO) mice. Intraperitoneal administration of ketamine or its enantiomers 10 min before the tail-suspension test exerted...
作者:Hideko Yamamoto , Etsuko Kamegaya , Yoko Hagino ...
来源:[J].Neuropharmacology(IF 4.114), 2017, Vol.112, pp.188-197Elsevier
摘要:... The GluN2D subunit of the NMDA receptor has low expression in the mature brain, and its role is not fully understood. In the present study, the effects of GluN2D subunit deficiency on emotional and cognitive function were investigated in GluN2D knockout (KO) mice. We found ...
作者:Hassan A. Alsaad , Nicholas W. DeKorver , Zhihao Mao ...
来源:[J].Neurochemical Research(IF 2.125), 2019, Vol.44 (1), pp.61-77Springer
摘要:... While the actions of the predominate GluN2 NMDAR subunits, GluN2A and GluN2B are relatively well understood, the function of GluN2C and GluN2D subunits in the telencephalon is largely unknown. To better understand the possible role of GluN2C subunits, we used fluorescence in ...
作者:Vivek Gautam , Jonathan C. Trinidad , Ronald A. Rimerman ...
来源:[J].Neuropharmacology(IF 4.114), 2013, Vol.74, pp.96-107Elsevier
摘要:... In this study, we used a series of tagged, carboxy terminal constructs of GluN2D to identify associating proteins from rat brain. Of seven different GluN2D C-terminal fragments used as bait, only the construct containing amino acids 983–1097 associated with an E3 ubiqui...
作者:Toshifumi Yamamoto , Tomomi Nakayama , Junji Yamaguchi ...
来源:[J].Neuroscience Letters(IF 2.026), 2016, Vol.610, pp.48-53Elsevier
摘要:... Even three administrations of ketamine, daily or weekly, induced a rapid increase in locomotor activity in wild-type (WT), but not in GluN2D knockout (GluN2D-KO) mice. Furthermore, for WT mice receiving daily ketamine, elevated locomotor activity was maintained after a 1-...
作者:Swanger Sharon A. , Vance Katie M. , Pare Jean-François ...
来源:[J].Journal of Neuroscience(IF 6.908), 2015, Vol.35 (48), pp.15971-15983The Royal Society
摘要:The GluN2D subunit of the NMDA receptor is prominently expressed in the basal ganglia and associated brainstem nuclei, including the subthalamic nucleus (STN), globus pallidus, striatum, and substantia nigra. However, little is known about how GluN2D-containing NMDA receptor...
作者:Kamalesh B. Ruppa , Dalton King , Richard E. Olson
来源:[J].Annual Reports in Medicinal Chemistry(IF 1.611), 2012, Vol.47, pp.89-103Elsevier
摘要:... Novel antagonist or modulator ligands for GluN2A, GluN2C, and GluN2D are just emerging. This chapter review discusses the recent research and developments in the area of GluN2B receptors and other receptor subtypes
作者:Xiaoqun Zhang , Ze‐Jun Feng , Karima Chergui
来源:[J].Journal of Neurochemistry(IF 3.973), 2014, Vol.129 (4), pp.581-590Wiley
摘要:... Through the use of amperometry and field potential recordings in mouse brain slices, we found that NMDAR s that contain the GluN2D subunit contribute to NMDA ‐induced inhibition of evoked dopamine release and of glutamatergic neurotransmission in the striatum of control...
作者:Amandine Jullienne , Axel Montagne , Cyrille Orset ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2011, Vol.6 (1)Springer
摘要:... At the molecular level, it has been proposed that the pro-neurotoxicity mediated by tPA might occur through extrasynaptic NMDAR containing the GluN2D subunit. Thus, selective antagonists targeting tPA/GluN2D-containing NMDAR signaling would be of interest to prevent noxious e...
作者:P S Suryavanshi , R R Ugale , D Yilmazer‐Hanke ...
来源:[J].British Journal of Pharmacology(IF 5.067), 2014, Vol.171 (3), pp.799-809Wiley
摘要:... NMDA receptor sub‐types differ in their subunit composition, with varied GluN2 subunits ( GluN2A ‐ GluN2D ) imparting different physiological, biochemical and pharmacological properties. CIQ is a positive allosteric modulator that is selective for GluN2C / GluN2D ‐con...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×