全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Lei Yin , Youying Mao , Hejie Song ...
来源:[J].Cell & Bioscience(IF 3), 2017, Vol.7 (1)Springer
摘要:... In both in vitro and in vivo models, VCR suppresses ADR-induced overexpression of α3β1 integrin and focal adhesion kinase (FAK). These data suggest that VCR may relieve ADR-induced nephropathy through inhibiting injury-induced activation of integrin outside-in signaling ...
作者:Hong-Yi Chen , Mei-Hui Lin , Chien-Cheng Chen ...
来源:[J].BMC Microbiology(IF 3.104), 2017, Vol.17 (1)Springer
摘要:Fibronectin (Fn) plays a major role in the attachment of Staphylococcus aureus to host cells by bridging staphylococcal fibronectin-binding proteins (FnBPs) and cell-surface integrins. A previous study demonstrated that the phagocytosis of S. aureus by macrophages is enhanced in ...
作者:Andrei B. Belousov , Joseph D. Fontes , Moises Freitas-Andrade ...
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:Gap junctions are unique membrane channels that play a significant role in intercellular communication in the developing and mature central nervous system (CNS). These channels are composed of connexin proteins that oligomerize into hexamers to form connexons or hemichannels. Man...
作者:Yo-Chen Chang , Yuh-Shin Chang , Ming-Chu Hsieh ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2016, Vol.132 (4), pp.262-270Elsevier
摘要:... Adhesion kinetics with or without ATRA treatment were profiled by adhesion assay. Surface coating with type IV collagen, fibronectin, laminin, but not type I collagen, significantly enhanced adhesion and spreading of ARPE-19 cells, while ATRA at subtoxic doses (ranging from...
作者:Guodong Tie , Yongqiang Tian , Shuyi Chen ...
来源:[J].Chinese Science Bulletin(IF 1.319), 2003, Vol.48 (5), pp.475-479Springer
摘要:Abstract(#br)The interaction of extracellular matrix-integrin markedly influences the adhesion, outgrowth, differentiation and expression of serine proteinases by the blastocyst, so it is regarded as a vital factor in blastocyst implantation. Although the mechanism of extracellu...
作者:Chunyu Zhang , Enkui Duan , Yujing Cao ...
来源:[J].Chinese Science Bulletin(IF 1.319), 1998, Vol.43 (17), pp.1473-1480Springer
摘要:Abstract(#br)Mouse embryo implantation is a complex process that includes trophoblast cells derived from ectoplacental cone (EPC) adhesion to and migration through the extracellular matrix (ECM) of uterine endometrium and invasion into the decidua. At the time of implantation, ...
作者:Jin-Shuen Chen , Herng-Sheng Lee , Jong-Shiaw Jin ...
来源:[J].Journal of Biomedical Science(IF 2.458), 2004, Vol.11 (2), pp.142-151Springer
摘要:Abstract(#br)Hyperglycemia and mannitol activate protein kinase C (PKC) and induce mesangial cell hypocontractility that subsequently may modulate renal function. Since focal adhesion kinase (FAK) activation is known to be linked with PKC activity, FAK may also be involved i...
作者:Christine J. Oates , Weiyan Wen , Douglas W. Hamilton
来源:[J].Materials(IF 2.247), 2011, Vol.4 (5), pp.893DOAJ
摘要:Changes of titanium surface roughness and surface free energy may influence protein absorption that increases cell differentiation through activation of focal adhesion kinase related pathways. However, the influence of titanium surface roughness and hydrophilicity on fibroblast ...
作者:Guang-Pu Fan , Wei Wang , Hui Zhao ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2015, Vol.37 (2), pp.515-526DOAJ
摘要:Background: To investigate the role of focal adhesion kinase (FAK)-mediated signaling in hypoxia-induced cardiac fibroblasts (CFs) differentiation and cardiac fibrosis post-myocardial infarction (MI) on a mice model. Methods: CFs of neonatal C57BL/6 mice were treated under n...
作者:Dale D. Tang , Brennan D. Gerlach
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)Springer
摘要:... c-Abl tyrosine kinase plays a critical role in regulating actin dynamics and migration of airway smooth muscle cells and nonmuscle cells. Recent studies suggest that intermediate filaments undergo reorganization during migration, which coordinates focal adhesion dynamics, cel...

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