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作者:Elham Ansarifar , Fakhri Shahidi , Mohebbat Mohebbi ...
来源:[J].LWT(IF 2.546), 2019, Vol.115
摘要:Abstract(#br)Fibril from food-grade materials is an important fundamental area of current researches in food systems. At first, in this study emulsifying properties of non-heated soy protein isolate (native SPI) and SPI fibril were compared. Then, the optimal concentration of SPI...
作者:Allan Speed , Alexander Groetsch , J. Jakob Schwiedrzik ...
来源:[J].Journal of the Mechanical Behavior of Biomedical Materials(IF 2.368), 2020, Vol.105
摘要:... For both criteria apparent yield stress of the mineralised collagen fibril decreased to 25.3–31.4% when varying fibril orientation from 0° to 90°. This study identified yield properties of extrafibrillar matrix using an aligned mineralised tissue. The ability to obtai...
作者:Chiharu Mizuguchi , Mitsuki Nakamura , Naoko Kurimitsu ...
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (Pt 1), pp.48-60
摘要:Abstract(#br)Here, we examined the effects of phosphatidylserine (PS) and cholesterol on the fibril-forming properties of the N-terminal 1‒83 fragment of an amyloidogenic G26R variant of apoA-I bound to small unilamellar vesicles. A thioflavin T fluorescence assay togethe...
作者:Jiranuwat Sapudom , Liv Kalbitzer , Xiancheng Wu ...
来源:[J].Biomaterials(IF 7.604), 2019, Vol.193, pp.47-57
摘要:... An increase of collagen fibril diameter and lysyl-oxidase mediated crosslinking has been observed in advanced tumor stages. Many current reports suggest that the local mechanical properties of single fibrillar components dominantly regulate cancer cell behavior. Here, we dem...
作者:Kseniia Afitska , Anastasiia Priss , Dmytro A. Yushchenko ...
来源:[J].Journal of Molecular Biology(IF 3.905), 2020, Vol.432 (4), pp.967-977
摘要:... Inhibition of the fibril growth is considered a promising therapeutic approach. However, the majority of the existing inhibitors are either unspecific or work at high micromolar concentrations. Earlier, we created a protein-based inhibitor of α-synuclein fibril growth th...
作者:Javed Masood Khan , Mohd. Shahnawaz Khan , Atiyatul Qadeer ...
来源:[J].Colloids and Surfaces A: Physicochemical and Engineering Aspects(IF 2.108), 2017, Vol.522, pp.494-502
摘要:... In order to develop drug condidate which can dissolve the amyloid fibrils and turned protein functional, it is urgent need to elucidate the mechanism of amyloid fibril formation under different conditions. In this study, we have taken a step to find the mechanism of amyloid fibril...
作者:Tim Bevan , Nadege Merabet , Jack Hornsby ...
来源:[J].Journal of Biomechanics(IF 2.716), 2018, Vol.74, pp.192-196
摘要:... Mechanical behaviour at low stretches is governed by fibril straightening, transitioning into load-bearing at recruitment stretch, resulting in a tissue stiffening effect. Previous investigations have suggested theoretical relationships between stress-stretch measurements and...
作者:J.S. Espinoza Ortiz , Cristiano L. Dias
来源:[J].Physica A: Statistical Mechanics and its Applications(IF 1.676), 2018
摘要:... This model is then extended to take into account proteins that can aggregate forming amyloid-like fibril structures. Changes to the model were guided by our current understanding of the thermodynamics of fibril formation. We provide analytical equations for different thermod...
作者:Raphaela Araujo Mantovani , Guilherme de Figueiredo Furtado , Flavia Maria Netto ...
来源:[J].Journal of Food Engineering(IF 2.276), 2018, Vol.223, pp.99-108
摘要:Abstract(#br)The effect of pH and mechanical processes on non-heated whey protein isolate (WPI) and WPI fibril was evaluated from structural, physical and emulsifying properties. Fibril aggregation was observed increasing pH from 2 to 7 whilst mechanical processes with high energ...
作者:Liv Kalbitzer , Tilo Pompe
来源:[J].Acta Biomaterialia(IF 5.093), 2018, Vol.67, pp.206-214
摘要:... Various physicochemical parameters of buffer conditions for in vitro fibril formation are well known, including pH-value, ion concentrations and temperature. However, there is a lack of a detailed understanding of reconstituting well-defined 3D network topologies, which is re...

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