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作者:Pan Meng , Shanshan Zhang , Xuejun Jiang ...
来源:[J].Ecotoxicology and Environmental Safety(IF 2.203), 2020, Vol.194
摘要:Abstract(#br)Ferroptosis is a newly identified form of cell death characterized by accumulation of intracellular iron and requirement of lipid peroxidation. However, whether arsenite triggers testicular cell death via ferroptosis remains unclear. In this study, after administrati...
作者:Huizhong Feng , Kenji Schorpp , Jenny Jin ...
来源:[J].Cell Reports, 2020, Vol.30 (10), pp.3411-3423.e7
摘要:Summary(#br)Ferroptosis is a type of regulated cell death driven by the iron-dependent accumulation of oxidized polyunsaturated fatty acid-containing phospholipids. There is no reliable way to selectively stain ferroptotic cells in tissue sections to characterize the extent of ferroptosis...
作者:Yan Chen , Ning Li , Haijing Wang ...
来源:[J].Life Sciences(IF 2.555), 2020, Vol.247
摘要:... The cycle-related proteins, ferroptosis-related protein, autophagy-related protein, and the phosphorylation of AMPK, mTOR and p70S6K were analyzed by western blotting. The autophagic flux was observed by transfecting cells with mRFP-GFP-LC3 plasmids. The xenograft murine mode...
作者:Haiyang Zhang , Ting Deng , Rui Liu ...
来源:[J].Molecular Cancer(IF 5.134), 2020, Vol.19 (14), pp.646-674Springer
摘要:Abstract(#br)Background(#br)Ferroptosis is a novel mode of non-apoptotic cell death induced by build-up of toxic lipid peroxides (lipid-ROS) in an iron dependent manner. Cancer-associated fibroblasts (CAFs) support tumor progression and drug resistance by secreting various bioact...
作者:Khatereh Khorsandi , Zahra Kianmehr , Zohreh hosseinmardi ...
来源:[J].Cancer Cell International(IF 2.093), 2020, Vol.20 (1), pp.61-38Springer
摘要:... The apoptosis and ferroptosis assays confirmed the MTT results which combination treatment with low-level laser and then GA increase the cell death probably via apoptosis and ferroptosis cell death mechanisms compared to GA alone. Conclusions(#br)This study suggests that low-...
作者:Minyi Xu , Jin Tao , Yidong Yang ...
来源:[J].Cell Death & Disease(IF 6.044), 2020, Vol.11 (2), pp.1756-1770Springer
摘要:Abstract(#br)Ferroptosis has recently emerged as an iron-dependent form of nonapoptotic cell death, which is also a regulated necrosis process and a response to tumor suppression. However, whether ferroptosis is involved in ulcerative colitis (UC) is unknown. The aims of this s...
作者:Niloofar Rashidipour , Somayyeh Karami-Mohajeri , Ali Mandegary ...
来源:[J].Toxicology(IF 4.017), 2020, Vol.433-434Elsevier
摘要:... Ferroptosis is the result of the loss of glutathione peroxidase 4 (GPX4) activity that transforms iron-dependent lipid hydroperoxides to lipid alcohols, which are inert in the biological environment. Impaired iron metabolism and lipid peroxidation are increasingly known as th...
作者:Yu-Jing He , Xiao-Ying Liu , Lei Xing ...
来源:[J].Biomaterials(IF 7.604), 2020, Vol.241Elsevier
摘要:Abstract(#br)Ferroptosis, a newfound non-apoptotic cell death pathway, results from the accumulation of iron-dependent lipid peroxide (LPO). Recently, emerging iron-based nanomaterials have been extensively developed to induce Fenton reaction-dependent ferroptosis for cancer ther...
作者:Zhaoxin Hu , Hao Zhang , Bin Yi ...
来源:[J].Cell Death & Disease(IF 6.044), 2020, Vol.11 (1), pp.756-766Springer
摘要:... Ferroptosis was recently reported to be involved in AKI. Here in this study, we investigated the internal relation between ferroptosis and the protective effect of VDR in cisplatin induced AKI. By using ferroptosis inhibitor ferrostatin-1 and measurement of ferroptotic cell d...
作者:Liyan Hou , Ruixue Huang , Fuqiang Sun ...
来源:[J].Toxicology(IF 4.017), 2019, Vol.417, pp.64-73Elsevier
摘要:... Ferroptosis, a recently recognized form of regulated cell death, has been implicated in the pathogenesis of multiple neurodegenerative diseases. This study is designed to investigate whether ferroptosis is involved in NADPH oxidase-regulated dopaminergic neurotoxicity. In vit...

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