全部文献期刊会议图书|学者科研项目
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作者:G. Alessandro Digesu , Elena Verdi , Linda Cardozo ...
来源:[J].Urology(IF 2.424), 2012, Vol.80 (1), pp.48-54
摘要:Objective(#br)To evaluate the efficacy and safety of elocalcitol in the treatment of women with overactive bladder and idiopathic detrusor overactivity.(#br)Methods(#br)The study was a multicenter, double-blind, randomized, placebo-controlled, parallel-group trial of women with ...
作者:Cristina Antinozzi , Clarissa Corinaldesi , Carla Giordano ...
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2017, Vol.167, pp.169-181
摘要:... We aim to evaluate in vitro the effect of elocalcitol, a non-hypercalcemic VDR agonist, on the biomolecular metabolic machinery of human skeletal muscle cells (Hfsmc), vs. insulin (I). We analyzed GLUT4, Flotillin-1, Caveolin-3 and Caveolin-1 cell expression/localization; mTO...
作者:Luciano Adorini , Giuseppe Penna , Susana Amuchastegui ...
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2007, Vol.103 (3-5), pp.689-693
摘要:... Preclinical data demonstrate that VDR agonists, and notably BXL-628 (elocalcitol), reduce the static component of BPH by inhibiting the activity of intra-prostatic growth factors downstream of the androgen receptor, and the dynamic component by targeting bladder cells. In add...
作者:Tomi Streng , Karl‐Erik Andersson , Petter Hedlund ...
来源:[J].BJU International(IF 3.046), 2012, Vol.110 (2b), pp.E125-E131
摘要:...(#br)It has previously been shown that elocalcitol might protect bladder contractile function in experimental models and that elocalcitol has beneficial effects in patients with LUTS. In humans, elocalcitol was demonstrated with a very good safety profile but only exhibited l...
作者:Won Seok Yang , Hoon Yu , Jin Ju Kim ...
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2016, Vol.155, pp.18-25
摘要:...(#br)25-Hydroxyvitamin D 3 (25D 3 ), a precursor of 1,25D 3 , and elocalcitol, an analog of 1,25D 3 , caused ectodomain shedding of TNFR1 within 30 min, whereas 1,25-dihydroxyvitamin D 2 (1,25D 2 ) and paricalcitol, a derivative of 1,25D 2 , did not. Both 25D 3 and elocalcitol...

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