全部文献期刊会议图书|学者科研项目
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作者:Hongzhou Lu
来源:[J].BioScience Trends(IF 1.582), 2020
摘要:... At present, there is no vaccine or antiviral treatment for human and animal coronavirus, so that identifying the drug treatment options as soon as possible is critical for the response to the 2019-nCoV outbreak. Three general methods, which include existing broad-spectrum ant...
作者:Alexandros G. Asimakopoulos , Pranav Kannan , Sean Higgins ...
来源:[J].Analytical and Bioanalytical Chemistry(IF 3.659), 2017, Vol.409 (26), pp.6205-6225
摘要:A liquid chromatography-triple quadrupole-tandem mass spectrometry (LC-qQq-MS/MS) method was developed for simultaneous determination of 89 legal neuropsychiatric pharmaceuticals and illicit drugs (both parent compounds and metabolites) and other micropollutants in unfiltered...
作者:Jill S. Waibel , Ashley Rudnick , Deborah R. Shagalov ...
来源:[J].Advances in Therapy(IF 2.125), 2017, Vol.34 (8), pp.1840-1849
摘要:Ablative fractional lasers (AFXL) enhance uptake of therapeutics and this newly emerging field is called laser-assisted drug delivery (LAD). This new science has emerged over the past decade and is finding its way into clinical practice. LAD is poised to change how medicine deliv...
作者:Shivani Kumar , Suman Chowdhury , Suresh Kumar
来源:[J].BMC Neuroscience(IF 3), 2017, Vol.18 (1)
摘要:... Drug repurposing offers an opportunity to reinvigorate the slowing drug discovery process by finding new uses for existing drugs. The major advantage of the drug repurposing approach is that the safety issues are already investigated in the clinical trials and the drugs are ...
作者:Katarína Maráková , Juraj Piešťanský , Peter Mikuš
来源:[J].Chromatographia(IF 1.437), 2017, Vol.80 (4), pp.537-546
摘要:A capillary electrophoresis (CE) method hyphenated with tandem mass spectrometry (triple quadrupole, QqQ MS) was developed for the simultaneous determination of six selected drugs used in Crohn’s disease treatment, namely, azathioprine, 6-thioguanine, 6-mercaptopurine, mesa...
作者:Lin Cong , Yong Liao , Suteng Yang ...
来源:[J].Mycopathologia(IF 1.489), 2017, Vol.182 (9-10), pp.829-837
摘要:... asahii ) is an opportunistic pathogen that can cause life-threatening infections in immunocompromised patients, with high mortality rates up to 80% despite treated with antifungal drugs. The biofilms-forming ability of T. asahii on indwelling medical devices may account for ...
作者:Pierre-André Billat , Franck Saint-Marcoux
来源:[J].Analytical and Bioanalytical Chemistry(IF 3.659), 2017, Vol.409 (25), pp.5837-5853
摘要:Understanding the efficacy and/or toxicity of most drugs requires effective intracellular measurements of the drug and its metabolites. Nevertheless, the most common plasma marker of the biological effect of the drug is the area under the curve. Compared with drug determination ...
作者:Isabella S. Sørensen , Christian Janfelt , Mette Marie B. Nielsen ...
来源:[J].Analytical and Bioanalytical Chemistry(IF 3.659), 2017, Vol.409 (21), pp.4993-5005
摘要:Study of skin penetration and distribution of the drug compounds in the skin is a major challenge in the development of topical drug products for treatment of skin diseases. It is crucial to have fast and efficacious screening methods which can provide information concerning the ...
作者:Shu-Wen Xue , Jing Li , Li Xu
来源:[J].Analytical and Bioanalytical Chemistry(IF 3.659), 2017, Vol.409 (12), pp.3103-3113
摘要:... Its application was demonstrated by magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs coupled to high performance liquid chromatography-UV analysis. Under the optimal conditions, the proposed method showed broad linear range of 1–5000 ng mL...
作者:Emina Mehanović , Harsheth Kaur Virk , Ibanga Akanidomo ...
来源:[J].Drug and Alcohol Dependence(IF 3.141), 2020, Vol.206
摘要:Abstract(#br)Background(#br)The burden of cannabis and other illicit drug use among youth represent a serious public health problem. The aim of the present study is to explore factors associated with cannabis and other illicit drug use among Nigerian secondary school adolesce...

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