全部文献期刊会议图书|学者科研项目
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作者:Andrea De Luca , Zita Jorge Sidumo , Giacomo Zanelli ...
来源:[J].BMC Infectious Diseases(IF 3.025), 2017, Vol.17 (1)Springer
摘要:We describe the accumulation of HIV-1 drug resistance and its effect on the activity of next-line components in patients with virological failure (HIV-1 RNA >1000 copies/mL) after 1 year (t1) of first-line antiretroviral therapy (ART) not switching to second-line drugs for one ad...
作者:Malek Chouchi , Wajih Kaabachi , Hedia Klaa ...
来源:[J].BMC Neurology(IF 2.564), 2017, Vol.17 (1)Springer
摘要:Antiepileptic drugs (AEDs) are effective medications available for epilepsy. However, many patients do not respond to this treatment and become resistant. Genetic polymorphisms may be involved in the variation of AEDs response. Therefore, we conducted an updated systematic review...
作者:Huaifu Dong , Huiping Cao , Haiyan Zheng
来源:[J].BMC Pediatrics(IF 1.982), 2017, Vol.17 (1)Springer
摘要:This study aimed to summarize common pathogens and associated drug resistance in neonatal sepsis (NS).
作者:Vu Quoc Dat , Hieu Ngoc Vu , Hung Nguyen The ...
来源:[J].BMC Infectious Diseases(IF 3.025), 2017, Vol.17 (1)Springer
摘要:Bloodstream infections (BSIs) are associated with high morbidity and mortality worldwide. However their aetiology, antimicrobial susceptibilities and associated outcomes differ between developed and developing countries. Systematic data from Vietnam are scarce. Here we present ae...
作者:Cheng-Yu Yang , Cheng-Chih Hsieh , Chih-Kung Lin ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
摘要:... This study investigated the antiproliferative effects of a Danshen extract on human oral cancer SAS, SCC25, OEC-M1, and KB drug-resistant cell lines and elucidated the possible underlying mechanism.
作者:Shu-Jung Lai , I-Fan Tu , Wan-Ling Wu ...
来源:[J].BMC Microbiology(IF 3.104), 2017, Vol.17 (1)Springer
摘要:Phosphorylation of amino acid residues on proteins is an important and common post-translational modification in both eukaryotes and prokaryotes. Most research work has been focused on phosphorylation of serine, threonine or tyrosine residues, whereas phosphorylation of other ami...
作者:Mohammad Hassan Moshafi , Saeid Ghasemshirazi , Ardavan Abiri
来源:[J].Medical Hypotheses(IF 1.054), 2020
摘要:Abstract(#br)The development of drug resistance is one of the most significant challenges of the current century in the pharmaceutical industry. Superinfections, cancer chemoresistance, and resistance observed in many non-infectious diseases are nullifying the efforts and monetar...
作者:Qiang Gao , Xiu-xiu Li , Yi-ming Xu ...
来源:[J].Cancer Letters(IF 4.258), 2020, Vol.476, pp.67-74
摘要:Abstract(#br)Drug resistance is a big problem in cancer treatment and one of the most prominent mechanisms underlain is overexpression of ATP-binding cassette (ABC) transporters, particularly ABCB1, ABCC1 and ABCG2. Inhibition of ABC transporters is an important approach to ove...
作者:Wan-mei Song , Yi-fan Li , Jin-yue Liu ...
来源:[J].Respiratory Medicine(IF 2.585), 2020, Vol.163
摘要:Abstract(#br)Background(#br)Although the association between diabetes mellitus (DM) and tuberculosis (TB) has been well-documented for centuries, evidence of the link between diabetes and drug resistance among previously treated TB patients remains limited and inconsistent.(#br...
作者:Wamidh H. Talib
来源:[J].Nutrition(IF 2.859), 2020, Vol.72
摘要:... However, the emergence of resistance to chemotherapeutic agents is still a major obstacle in the successful management of resistant tumors. Therefore, development of new mechanisms to overcome drug resistance is essential and may be further developed into effective therapies ...

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