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作者:Marília Berlofa Visacri , Eder de Carvalho Pincinato , Graziele Baldan Ferrari ...
来源:[J].DARU Journal of Pharmaceutical Sciences, 2017, Vol.25 (1)
摘要:... however, it causes significant adverse drug reactions (ADRs). Potential pharmacokinetic markers must be studied to predict or prevent cisplatin-induced ADRs and achieve better prognosis. This study was designed to investigate the relationship between ADRs and kinetics of cisp...
作者:Olivia Wilcox , Mohamed Hassanein , John Armstrong ...
来源:[J].BMC Pulmonary Medicine(IF 2.76), 2017, Vol.17 (1)
摘要:Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity drug reaction involving the skin and multiple internal organ systems. The symptoms typically present with fever and skin rash, and rapidly progress to multiple organ failures. Vancomycin is...
作者:Wiparat Manuyakorn , Plernpit Likkasittipan , Sukanya Wattanapokayakit ...
来源:[J].Epilepsy Research(IF 2.241), 2020
摘要:Abstract(#br)Purpose(#br)Phenytoin (PHT) is a common causative drug for severe cutaneous adverse drug reactions (SCARs) in children. SCARs, including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TE...
作者:Ayşe Kaçar Bayram , Mehmet Canpolat , Salih Levent Çınar ...
来源:[J].Journal of Emergency Medicine(IF 1.331), 2016, Vol.50 (2), pp.e61-e66
摘要:Abstract(#br)Background(#br)Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare, life-threatening hypersensitivity drug reaction. Patients present with cutaneous rash, fever, lymphadenopathy, hematologic abnormalities with eosinophilia and atypical ly...
作者:Janine Arnott , Hannah Hesselgreaves , Anthony J Nunn ...
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.7 (10)
摘要:There is little research on parents' experiences of suspected adverse drug reactions in their children and hence little evidence to guide clinicians when communicating with families about problems associated with medicines.To identify any unmet information and communication needs...
作者:Arantza Casillas , Alicia Pérez , Maite Oronoz ...
来源:[J].Expert Systems With Applications(IF 1.854), 2016, Vol.61, pp.235-245
摘要:Abstract(#br)Objective : To tackle the extraction of adverse drug reaction events in electronic health records. The challenge stands in inferring a robust prediction model from highly unbalanced data. According to our manually annotated corpus, only 6% of the drug-disease entity ...
作者:Kingston Rajiah , Mari Kannan Maharajan , Shashina Nair
来源:[J].Saudi Pharmaceutical Journal(IF 0.954), 2016, Vol.24 (5), pp.600-604
摘要:Abstract(#br)Pharmacy students’ knowledge about adverse drug reaction reporting can impact their attitude towards patient care and issues on patient safety. The aim of this study was to investigate the knowledge and perception of pharmacy students about adverse drug reaction...
作者:Leàn Rolfes , Florence van Hunsel , Laura van der Linden ...
来源:[J].Drug Safety(IF 3.408), 2017, Vol.40 (7), pp.607-614
摘要:Clinical information is needed to assess the causal relationship between a drug and an adverse drug reaction (ADR) in a reliable way. Little is known about the level of relevant clinical information about the ADRs reported by patients.
作者:F Kheloufi , A Default , F Rouby ...
来源:[J].European Journal of Clinical Pharmacology(IF 2.741), 2017, Vol.73 (8), pp.1009-1018
摘要:... We aim to describe the patterns of patient adverse drug reaction (ADR) reporting in France and estimate the contribution of a review by a PVC assessor on the informativeness of these reports.
作者:James W. S. Young , Neil H. Shear
来源:[J].Drugs & Aging(IF 2.646), 2017, Vol.34 (9), pp.655-672
摘要:Cutaneous adverse drug reactions comprise a significant proportion of all adverse drug reactions. They may mimic other dermatologic or systemic illnesses and may cause significant morbidity or mortality. Seven morphologic groups encompass the most commonly encountered cutaneous drug reaction...

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