全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Liv B. Gansmo , Merete Bjørnslett , Mari Kyllesø Halle ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:The del1518 (rs3730485) polymorphism is an in/del variant in the MDM2 promoter P1. The variant is in complete linkage disequilibrium with MDM2 SNP309 (rs2279744) and has previously been found associated with an increased risk of colon cancer. In this study we assessed the impact ...
作者:Hua WF , Zhang A , Duan P ...
来源:[J].OncoTargets and Therapy(IF 2.073), 2017, Vol.Volume 10, pp.3773-3780DOAJ
摘要:... The association of del1518 polymorphism (rs3730485) in the MDM2 promoter with cancer susceptibility has been extensively studied; however, the results are contradictory. To quantify the association between this polymorphism and overall cancer risk, we conducted a meta-an...
作者:Wenfeng Hua , Anqi Zhang , Ping Duan ...
来源:[J].OncoTargets and Therapy(IF 2.073), 2017, Vol.2017 (default), pp.3773-3780Dove
摘要:... The association of del1518 polymorphism (rs3730485) in the MDM2 promoter with cancer susceptibility has been extensively studied; however, the results are contradictory. To quantify the association between this polymorphism and overall cancer risk, we conducted a meta-analysi...
作者:Gansmo Liv B , Vatten Lars , Romundstad Pål ...
来源:[J].Oncotarget(IF 6.636), 2016, Vol.7 (19), pp.28637-46PubMed
摘要:... del1518 (rs3730485) is an indel polymorphism residing in the MDM2 promoter P1 and is in almost complete linkage disequilibrium with the MDM2 promoter P2 polymorphism SNP309T>G (rs2279744). Cancer risk assessments of del1518 have previously been conducted in relatively smal...
作者:Gallegos-Arreola Martha Patricia , Márquez-Rosales María Guadalupe , Sánchez-Corona José ...
来源:[J].Annals of clinical and laboratory science, 2017, Vol.47 (3), pp.291-297PubMed
摘要:... The data on the Del1518 promoter polymorphism in the MDM2 gene have revealed associations with cancer.;;We examined the role of the MDM2 Del1518 polymorphism through a comparison of the genotypes of 345 healthy Mexican women with those of 742 Mexican women with breast cancer ...
作者:Zhang Lin , Zhu Zhendong , Wu Hongyan ...
来源:[J].Annals of clinical and laboratory science, 2015, Vol.45 (4), pp.433-7PubMed
摘要:...The current study aims to investigate the association of SNP309 and del1518 polymorphisms as well as their haplotypes in MDM2 with the risk of esophageal squamous cell carcinoma (ESCC) in the Chinese population. This study included 132 patients with ESCC and 132 age-matched he...
作者:金明娟
来源:[D].浙江大学  2007CNKI
摘要:... 为验证上述研究假设,研究以我国结直肠癌高发县——浙江省嘉善县为研究现场,采用自然人群为基础的病例对照研究设计,以OGG1 Ser326Cys、XRCC1 Arg194Trp、XRCC1Arg280His、XRCC1 Arg399Gln、XPD Lys751Gln和XRCC3 Thr241Met等常见DNA修复基因多态以及P53 Intron3 16bp duplication、P53 Exon4 Arg72Pro、P53 Intron6 G/A transition、MDM2 Del1518...
被引频次:1下载频次:579
作者:Hongxia Ma , Zhibin Hu , Xiangjun Zhai ...
来源:[J].Cancer Letters(IF 4.258), 2005, Vol.240 (2), pp.261-267Elsevier
摘要:... To test the hypothesis that this functional variant in the MDM2 promoter is associated with risk of breast cancer, we conducted a molecular epidemiological study of 366 breast cancer cases (BC), 263 patients with benign breast diseases (BBD) and 605 cancer-free controls in China, in which we genotyped this T/G variant and another common insertion/deletion polymorphism (Del1518...
作者:曹延延
来源:[D].河北医科大学  2007CNKI
摘要:...本课题研究了MDM2启动子区SNP309、Del1518以及53BP1启动子区T885G、外显子区P909L、W1488G基因多态性,与中国河北高发区人群食管鳞癌(esophageal squamous cell carcinoma, ESCC)和贲门腺癌(gastric cardiac adenocarcinoma, GCA)遗传易...
被引频次:-下载频次:92
作者:曹延延 , 张秀凤 , 郭炜 ...
来源:[J].肿瘤, 2007, (08), pp.628-632CNKI
摘要:目的:研究MDM2启动子区SNP309和Del1518基因多态性与中国河北省高发区人群食管鳞状细胞癌(esophagealsquamous cell carcinoma,ESCC)和贲门腺癌(gastric cardiac adenocarcinoma,GCA)易感性的关系。方法:应用引物引入限制性内切酶分析-聚...
被引频次:5下载频次:195

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