全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Robert Glyde , Fuzhou Ye , Vidya Chandran Darbari ...
来源:[J].Molecular Cell(IF 15.28), 2017, Vol.67 (1), pp.106-116.e4Elsevier
摘要:... For transcription to occur, the closed promoter complex (RPc), where DNA is double stranded, must isomerize into an open promoter complex (RPo), where the DNA is melted out into a transcription bubble and the single-stranded template DNA is delivered to the RNAP active si...
作者:Siva R. Wigneshweraraj , Dhruti Savalia , Konstantin Severinov ...
来源:[J].Journal of Molecular Biology(IF 3.905), 2006, Vol.359 (5), pp.1182-1195Elsevier
摘要:Abstract(#br)The bacterial RNA polymerase (RNAP) is a multi-subunit, structurally flexible, complex molecular machine, in which activities associated with DNA opening for transcription-competent open promoter complex (OC) formation reside in the catalytic β and β′ subunits ...
作者:Christian Dienemann , Björn Schwalb , Sandra Schilbach ...
来源:[J].Molecular Cell(IF 15.28), 2019, Vol.73 (1), pp.97-106.e4Elsevier
摘要:Summary(#br)Transcription initiation requires opening of promoter DNA in the RNA polymerase II (Pol II) pre-initiation complex (PIC), but it remains unclear how this is achieved. Here we report the cryo-electron microscopic (cryo-EM) structure of a yeast PIC that contains underwo...
作者:Y. Charles Li , David Retzloff
来源:[J].Mathematical Biosciences(IF 1.454), 2006, Vol.203 (1), pp.137-147Elsevier
摘要:Abstract(#br)We propose a dynamic model of DNA opening for replication and transcription. Numerical simulations on this model strongly indicate a phase transition mechanism of DNA opening.
作者:Helen George , Isao Kuraoka , David A. Nauman ...
来源:[J].Current Biology(IF 9.494), 2000, Vol.10 (2), pp.103-106Elsevier
摘要:Abstract(#br)The Escherichia coli RuvA and RuvB proteins promote the branch migration of Holliday junctions during the late stages of homologous recombination and DNA repair (reviewed in [1]). Biochemical and structural studies of the RuvAB–Holliday junction complex have show...
作者:Robert Glyde , Fuzhou Ye , Milija Jovanovic ...
来源:[J].Molecular Cell(IF 15.28), 2018, Vol.70 (6), pp.1111-1120.e3Elsevier
摘要:... Transcription initiation is a dynamic multi-step process that involves the opening of the double-stranded DNA to form a transcription bubble and delivery of the template strand deep into the RNAP for RNA synthesis. Applying cryoelectron microscopy to a unique transcription ...
作者:Srivithya Vellampatti , Sekhar Babu Mitta , Jang Ah Kim ...
来源:[J].Current Applied Physics(IF 1.814), 2015, Vol.15 (8), pp.851-856Elsevier
摘要:Abstract(#br)DNA is one of the most promising molecules for use in nanotechnology because it has a nanoscale size and also has the ability for self-assembly. In this paper, we discuss the use of free-solution growth for a 1D DNA open tube (OT) and substrate-assisted growth for ...
作者:Frédéric Coin , Valentyn Oksenych , Jean-Marc Egly
来源:[J].Molecular Cell(IF 15.28), 2007, Vol.26 (2), pp.245-256Elsevier
摘要:... A mutation found among XP-B patients (F99S) weakens this interaction and the resulting ATPase stimulation, thereby explaining the defect in the damaged DNA opening. We next found that mutations in the helicase motifs III (T469A) and VI (Q638A) that inhibit XPB helicase activi...
作者:Qi-zhuang Lv , Kang-kang Guo , Yan-ming Zhang
来源:[J].Virus Genes(IF 1.769), 2014, Vol.49 (1), pp.1-10Springer
摘要:... The genomic DNA of PCV2 is predicted to contain 11 open reading frames (ORFs) and at least seven potential ORFs-encoding proteins larger than 5 kDa. Currently, however, only five virally encoded proteins (Rep, Rep′, Cap, ORF3, and ORF4 protein) have been identified in P...
作者:Virginia Muto
来源:[J].Journal of Biological Physics(IF 0.951), 1993, Vol.19 (2), pp.113-122Springer
摘要:Abstract(#br)A two-dimensional anharmonic model, the so-called Toda-Lennard-Jones model, is considered in order to investigate the problems related to the lifetime of the open states precursors to full denaturation, in inhomogeneous ring-shaped DNA molecules. It is found that a t...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×