全部文献期刊会议图书|学者科研项目
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作者:Hongmao Sun , Yuhong Wang , Dorian M. Cheff ...
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2020
摘要:Abstract(#br)Cytotoxicity is a critical property in determining the fate of a small molecule in the drug discovery pipeline. Cytotoxic compounds are identified and triaged in both target-based and cell-based phenotypic approaches due to their off-target toxicity or on-target...
作者:Mayu Yasunaga , Yasuko Fujita , Rumiko Saito ...
来源:[J].BMC Biotechnology(IF 2.165), 2017, Vol.17 (1)Springer
摘要:... Generally, in the repeated treatment test to assess cytotoxicity in the spheroids, ATP assay, colorimetric measurement using pigments or high-content imaging analysis is performed. However, continuous assessment of cytotoxicity in the same spheroids using the above assays or ...
作者:Muhammad Imran Din , Farhan Arshad , Zaib Hussain ...
来源:[J].Nanoscale Research Letters(IF 2.524), 2017, Vol.12 (1)Springer
摘要:... CuNPs show catalytic, antibacterial, antioxidant, and antifungal activities along with cytotoxicity and anticancer properties in many different applications. Many physical and chemical methods have been used to synthesize nanoparticles including laser ablation, microwave-assi...
作者:Haiyun Guo , Zhengwu Peng , Liu Yang ...
来源:[J].BMC Anesthesiology(IF 1.188), 2017, Vol.17 (1)Springer
摘要:... However, little attention has been paid to exploring the possible cytotoxicity of inhalation anaesthetics, such as isoflurane, in astrocytes. In this research, we determined that prolonged exposure to an inhalation anaesthetic caused cytotoxicity in astrocytes, and we identif...
作者:Mattia Di Nunzio , Veronica Valli , Lidia Tomás-Cobos ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
摘要:... To avoid misleading results, concentration and chemical form, exposure time, and potential cytotoxicity of the tested bioactives should be carefully set prior to any other experiments.
作者:Kai Dai , Zubing Chen , Sha She ...
来源:[J].Immunobiology(IF 2.814), 2020
摘要:... In the present study, we investigated the role of LRCH1 in NK-92 cell cytotoxicity. LRCH1 was ablated in NK-92 cells through CRISP-Cas9-mediated knockout. LRCH1 knockout did not influence the basal behavior of NK-92 cells such as cell survival, expression of natural cytotoxicity...
作者:Maryam Poormontaseri , Saeid Hosseinzadeh , Seyed Shahram Shekarforoush ...
来源:[J].BMC Microbiology(IF 3.104), 2017, Vol.17 (1)Springer
摘要:Some Bacillus strains have recently been identified for potential use as probiotics and food additives. The present study evaluated the antimicrobial effects of Bacillus subtilis ATCC 6633 and its metabolite on the enterotoxin and vegetative cells, spore and germinated spore of C...
作者:Victor Kuete , Fabrice W. Fokou , Oğuzhan Karaosmanoğlu ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
摘要:Cancer still constitutes one of the major health concerns globally, causing serious threats on patients, their families, and the healthcare system.
作者:Jinhui Wang , Xinyi Niu , Jian Sun ...
来源:[J].Science of the Total Environment(IF 3.258), 2020, Vol.715
摘要:...5 emitted from E-waste has the highest cytotoxicity and special protections should be aimed at mitigating it. The Pearson correlation coefficient demonstrated that elemental carbon, heavy metals, and nitrated PAHs were strongly correlated with VSMC bioreactivity. Light elemen...
作者:Saba Hemmati , Ahmad Ahmeda , Yaser Salehabadi ...
来源:[J].Polyhedron(IF 1.813), 2020, Vol.180
摘要:... The purpose of the study was chemical characterization and assessment of cytotoxicity, antioxidant, antifungal, antibacterial, and cutaneous wound healing properties of copper nanoparticles (CuNPs) using the aqueous extract of Strawberry fruit and l -Ascorbic acid as reducin...

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