全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Valdet Uka , Geromy G. Moore , Natalia Arroyo-Manzanares ...
来源:[J].Toxins(IF 2.129), 2017, Vol.9 (1)DOAJ
摘要:Cyclopiazonic acid (α-cyclopiazonic acid, α-CPA) is an indole-hydrindane-tetramic acid neurotoxin produced by various fungal species, including the notorious food and feed contaminant Aspergillus flavus. Despite its discovery in A. flavus cultures approximately 40 years ago, ...
作者:Rocío Casquete , María José Benito , Emilio Aranda ...
来源:[J].Fungal Biology(IF 2.082), 2019Elsevier
摘要:Abstract(#br)Expression of genes associated with cyclopiazonic acid (CPA) biosynthesis by Penicillium strains in a cheese-based medium has not been previously studied. To control CPA biosynthesis, it would be useful to understand the changes in gene expression during cheese pr...
作者:Parisa Ansari , Georg Häubl
来源:[J].Food Chemistry(IF 3.334), 2016, Vol.211, pp.978-982Elsevier
摘要:Abstract(#br)For the determination of cyclopiazonic acid (CPA) in food and feed samples a simple and accurate LC–MS/MS method, which does not require extensive sample clean-up steps, was developed and validated. A fully carbon-13-labelled internal standard was used to compens...
作者:Dilek Heperkan , Sukran Somuncuoglu , Funda Karbancioglu-Güler ...
来源:[J].Food Control(IF 2.738), 2012, Vol.23 (1), pp.82-86Elsevier
摘要:Abstract(#br)Natural cyclopiazonic acid (CPA) and aflatoxin (AF) contamination were investigated in Aspergillus section Flavi positive dried fig samples collected from orchards after harvesting. Cyclopiazonic acid and AF were determined by thin layer chromatography (TLC) and high...
作者:Rui Cui , Yizhuo Wang , Liu Wang ...
来源:[J].Antiviral Research(IF 3.925), 2016, Vol.132, pp.38-45Elsevier
摘要:... To search for new anti-RSV agents, we developed a cell-based assay that measures inhibition of RSV-induced cytopathic effect (CPE) and identified cyclopiazonic acid (CPA), an intracellular calcium ATPase inhibitor as a RSV inhibitor (EC 50 values 4.13 μM) by screening of na...
作者:Maria L. Marin , Shu-Shyan Wong , James J. Pestka
来源:[J].Toxicology(IF 4.017), 1996, Vol.114 (1), pp.67-79Elsevier
摘要:Abstract(#br)The effects of the mycotoxin cyclopiazonic acid (CPA) on cytokine secretion and gene expression were evaluated in the WEHI-3 murine macrophage cell line. Lipopolysaccharide (LPS)-stimulated and non-stimulated cells were exposed to various concentrations of CPA a...
作者:Nolwenn Hymery , Floriane Masson , Georges Barbier ...
来源:[J].Toxicology in Vitro(IF 2.65), 2014, Vol.28 (5), pp.940-947Elsevier
摘要:Abstract(#br)In this study, in vitro cytotoxicity and immunotoxicity of the mycotoxin cyclopiazonic acid (CPA) was evaluated on human cells. To evaluate cytoxicity, several cellular targets were used (CD34+, monocytes, THP-1 and Caco-2). Monocytes were more sensitive to CPA than...
作者:Mariëlla E.M Kuilman-Wahls , Mònica Sabater Vilar , Lilian de Nijs-Tjon ...
来源:[J].Environmental Toxicology and Pharmacology(IF 2.005), 2002, Vol.11 (3), pp.207-212Elsevier
摘要:Abstract(#br)Cyclopiazonic acid and aflatoxin B 1 are mycotoxins which can both be produced by the same moulds. Men can be exposed to these mycotoxins directly via ingestion of plant-derived food, as well as, indirectly via consumption of animal products. Although it is well know...
作者:Yu Huang , Kwok-Kin Cheung
来源:[J].European Journal of Pharmacology(IF 2.592), 1997, Vol.332 (2), pp.167-172Elsevier
摘要:Abstract(#br)The action of cyclopiazonic acid, the putative inhibitor of the Ca 2+ -ATPase of endoplasmic reticulum, on phenylephrine-evoked isometric contractions in rat isolated mesenteric arteries were investigated. Cyclopiazonic acid (3 μ M) induced an initial relaxation f...
作者:A. Badaoui , C. Huchet-Cadiou , C. Léoty
来源:[J].Journal of Molecular and Cellular Cardiology(IF 5.148), 1995, Vol.27 (11), pp.2495-2505Elsevier
摘要:Abstract(#br)The effects of cyclopiazonic acid, a specific inhibitor of the sarcoplasmic reticulum Ca 2+ -ATPase, on membrane currents and contraction were investigated under voltage clamped conditions on frog atrial trabeculae using the double mannitol-gap technique. In Ring...

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