全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Jegan Iyyathurai , Jean-Paul Decuypere , Luc Leybaert ...
来源:[J].BMC Cell Biology(IF 2.808), 2016, Vol.17 (S1)Springer
摘要:Abstract(#br)Connexins mediate intercellular communication by assembling into hexameric channel complexes that act as hemichannels and gap junction channels. Most connexins are characterized by a very rapid turn-over in a variety of cell systems. The regulation of connexin turn-o...
作者:Thomas Desplantez
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:This review comes after the International Gap Junction Conference (IGJC 2015) and describes the current knowledge on the function of the specific motifs of connexins in the regulation of the formation of gap junction channels. Moreover the review is complemented by a summarized d...
作者:Daniela Begandt , Miranda E Good , Alex S. Keller ...
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:... Channels formed by connexins or pannexins that connect the intra- and extracellular compartments allow the release of paracrine signals, such as ATP and prostaglandins, and thus play a central role in achieving fine regulation and coordination of vascular function. This revie...
作者:Lina Rimkutė , Vaidas Jotautis , Alina Marandykina ...
来源:[J].BMC Cell Biology(IF 2.808), 2016, Vol.17 (1)Springer
摘要:... The morphology of TTs was not influenced by expression of examined connexins; however, Cx36-EGFP-expressing cells formed more TTs while cells expressing Cx43-EGFP, Cx45, and Cx47 formed fewer TTs between each other compared with wt and Cx40-CFP-expressing cells. Also, Cx...
作者:Viviana M. Berthoud , Anaclet Ngezahayo
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:The lens is an avascular organ composed of an anterior epithelial cell layer and fiber cells that form the bulk of the organ. The lens expresses connexin43 (Cx43), connexin46 (Cx46) and connexin50 (Cx50). Epithelial Cx50 has critical roles in cell proliferation and differentiatio...
作者:Joanna Gemel , Zihan Su , Alex Gileles-Hillel ...
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:Obstructive sleep apnea has been linked to the development of heart disease and arrhythmias, including atrial fibrillation. Since altered conduction through gap junction channels can contribute to the pathogenesis of such arrhythmias, we examined the abundance and distributions o...
作者:F. Villanelo , Y. Escalona , C. Pareja-Barrueto ...
来源:[J].BMC Cell Biology(IF 2.808), 2017, Vol.18 (1)Springer
摘要:Gap junction channels (GJCs) are massive protein channels connecting the cytoplasm of adjacent cells. These channels allow intercellular transfer of molecules up to ~1 kDa, including water, ions and other metabolites. Unveiling structure-function relationships coded into the mole...
作者:Gabriele Sala , Salvatore Badalamenti , Claudio Ponticelli
来源:[J].American Journal of Kidney Diseases(IF 5.294), 2016, Vol.67 (4), pp.677-687Elsevier
摘要:Connexins are membrane-spanning proteins that allow for the formation of cell-to-cell channels and cell-to–extracellular space hemichannels. Many connexin subtypes are expressed in kidney cells. Some mutations in connexin genes have been linked to various human pathologies,...
作者:Lilian I. Plotkin , Dale W. Laird , Joelle Amedee
来源:[J].BMC Cell Biology(IF 2.808), 2016, Vol.17 (S1)Springer
摘要:... These intercellular channels formed from connexins are present in bone forming osteoblasts, bone resorbing osteoclasts, and osteocytes (mature osteoblasts embedded in the mineralized bone matrix). More recently, genetic and pharmacologic studies revealed the role of connexins...
作者:Hideyuki eTakeuchi , Akio eSuzumura
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2014, Vol.8DOAJ
摘要:Microglia are macrophage-like resident immune cells that contribute to the maintenance of homeostasis in the central nervous system (CNS). Abnormal activation of microglia can cause damage in the CNS, and accumulation of activated microglia is a characteristic pathological o...

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