全部文献期刊会议图书|学者科研项目
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作者:Lining Zhang , Ruolan Song , Dongsheng Gu ...
来源:[J].Cell & Bioscience(IF 3), 2017, Vol.7 (1)Springer
摘要:Colorectal cancer is a leading cause of cancer-related mortality worldwide, with Fluorouracil (5-FU)-based chemotherapy as the major treatment for advanced disease. Many patients with advanced colorectal cancer eventually succumb to the disease despite some patients responded ini...
作者:Emilie Lereclus , Mira Tout , Alban Girault ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Colorectal cancer is a major public health issue worldwide. Interleukin-17 (IL-17) and Th17 (T-helper cell type 17)-related molecules are involved in tumor development and in resistance to bevacizumab, an anti-vascular endothelial growth factor monoclonal antibody used in associa...
作者:Bello Arkilla Magaji , Foong Ming Moy , April Camilla Roslani ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Colorectal cancer is the third most commonly diagnosed malignancy and the fourth leading cause of cancer-related death globally. It is the second most common cancer among both males and females in Malaysia. The economic burden of colorectal cancer is likely to increase over time ...
作者:Lenora W. M. Loo , Mathieu Lemire , Loïc Le Marchand
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:Genome-wide association studies have identified 55 genetic variants associated with colorectal cancer risk to date. However, potential causal genes and pathways regulated by these risk variants remain to be characterized. Therefore, we performed gene ontology enrichment and pathw...
作者:Jasmine Lee , Yin-Yi Xiao , Yan Yu Sun ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM . A non-hereditary, acquired process of hypermethylation ...
作者:Jiao Yang , Xianglin L. Du , Shuting Li ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Among colorectal cancer (CRC) survivors, how the prior tumor location affects the risk of subsequent primary colorectal cancer (SPCRC) and the outcome of those suffering from SPCRC remain unknown.
作者:Yoon Dae Han , Mahdi Hussain Al Bandar , Audrius Dulskas ...
来源:[J].BMC Surgery(IF 1.973), 2017, Vol.17 (1)Springer
摘要:Ulcerative colitis (UC) harbours a high risk of UC-associated colorectal cancer (UCCC), which is important cause of morbidity and mortality in patients with inflammatory bowel disease. Overall Survival (OS) of patients with UCCC has not been addressed well in the literature. Thus...
作者:John R. Stevens , Jennifer S. Herrick , Roger K. Wolff ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:microRNAs are small non-protein-coding RNA molecules that regulate gene expression, and have a potential epigenetic role in disease progression and survival of colorectal cancer. In terms of tumor-normal expression differences, many microRNAs exhibit evidence of being up-regul...
作者:Hege Berg Henriksen , Hanna Ræder , Siv Kjølsrud Bøhn ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Colorectal cancer survivors are not only at risk for recurrent disease but also at increased risk of comorbidities such as other cancers, cardiovascular disease, diabetes, hypertension and functional decline. In this trial, we aim at investigating whether a diet in accordance wit...
作者:Mariko Carey , Robert Sanson-Fisher , Finlay Macrae ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Colorectal cancer (CRC) survivors are at increased risk of developing the disease again. Surveillance guidelines are aimed at maximising the early detection of recurring or new cancers and pre-cancerous polyps. The frequency and type of surveillance recommended depends on the ty...

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