全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Sohyun Jeong , Minji Sohn , Jae Hyun Kim ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:Clinical trial globalization is a major trend for industry-sponsored clinical trials. There has been a shift in clinical trial sites towards emerging regions of Eastern Europe, Latin America, Asia, the Middle East, and Africa. Our study objectives were to evaluate the current...
作者:Abebaw Fekadu , Asrat Hailu , Eyasu Makonnen ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:Just over 2 years ago on 20 May 2014, we celebrated the first International Clinical Trial Day (ICTD) in Ethiopia at the College of Health Sciences, Addis Ababa University. The main aim of the celebration was to express solidarity with clinical researchers, particularly clinical ...
作者:Catrin Tudur Smith , Sarah Nevitt , Duncan Appelbe ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:Demands are increasingly being made for clinical trialists to actively share individual participant data (IPD) collected from clinical trials using responsible methods that protect the confidentiality and privacy of clinical trial participants. Clinical trialists, particularly th...
作者:Susan Eggly , Lauren M. Hamel , Elisabeth Heath ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Cancer clinical trials are essential for testing new treatments and represent state-of-the-art cancer treatment, but only a small percentage of patients ever enroll in a trial. Under-enrollment is an even greater problem among minorities, particularly African Americans, repr...
作者:Leonid Hanin
来源:[J].BMC Medical Research Methodology(IF 2.211), 2017, Vol.17 (1)Springer
摘要:One area of biomedical research where the replication crisis is most visible and consequential is clinical trials. Why do outcomes of so many clinical trials contradict each other? Why is the effectiveness of many drugs and other medical interventions so low? Why have prescrip...
作者:Per Winkel , Philip M. Bath , Christian Gluud ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:... In phase II trials, cooling awake patients with ischaemic stroke has been shown to be feasible and safe, but the effects in functional outcomes has not yet been investigated in an adequately sized randomised clinical trial.
作者:Gyuri Kim , Ji Cheol Bae , Byoung Kee Yi ...
来源:[J].BMC Medical Informatics and Decision Making(IF 1.603), 2017, Vol.17 (1)Springer
摘要:... The aim of this study is to examine the efficacy and safety of insulin dose adjustment based on a smartphone PHR application in patients with diabetes mellitus (DM) and to confirm the validity and stability of an information and communication technology (ICT)-based centralized clinical trial...
作者:Sudip Chatterjee , Richeek Pradhan
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:Arch and colleagues in their 24 October 2016 paper in Trials focus on the issue of centralised versus local measurement of glycated haemoglobin (HbA1c) in clinical trial settings. Resolution of the debate is important: while local HbA1c measurement is less costly, and would ther...
作者:Anna Kearney , Anne Daykin , Alison R. G. Shaw ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:The failure to retain patients or collect primary-outcome data is a common challenge for trials and reduces the statistical power and potentially introduces bias into the analysis. Identifying strategies to minimise missing data was the second highest methodological research prio...
作者:Julia Lawton , David White , David Rankin ...
来源:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
摘要:The ending of a clinical trial may be challenging, particularly if staff are required to withdraw the investigated treatment(s); however, this aspect of trial work is surprisingly under-researched. To address this gap, we explored the experiences of staff involved in closing out ...

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