全部文献期刊会议图书|学者科研项目
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作者:Yueting Peng , Zhongyuan Chen , Yu Chen ...
来源:[J].Acta Biomaterialia(IF 5.093), 2019, Vol.88, pp.86-101
摘要:... However, the biomechanical behavior of tumor cells and the underlying mechanotransduction pathways remain unclear. Here, we used polyacrylamide (PAA) substrates to simulate tissue stiffness at different progress stages of breast cancer in vitro , and we observed that moderat...
作者:Pilar Bayo , Adriana Jou , Albrecht Stenzinger ...
来源:[J].Molecular Oncology(IF 6.701), 2015, Vol.9 (8), pp.1704-1719
摘要:Abstract(#br)Recurrent gain on chromosome 3q26 encompassing the gene locus for the transcription factor SOX2 is a frequent event in human squamous cell carcinoma, including head and neck squamous cell carcinoma (HNSCC). Numerous studies demonstrated that SOX2 expression and funct...
作者:Miriam Bern , Alexander King , Derek A. Applewhite ...
来源:[J].BMC Bioinformatics(IF 3.024), 2019, Vol.20 (S12), pp.1-13
摘要:... Recently, both diseases have been associated with disrupted neuron motility and migration patterns, suggesting that aberrant cell motility is a phenotype for these neurological diseases. Results We formulate the Polygenic Disease Phenotype Problem which seeks to identify c...
作者:Atsuko Takatsuka , Reiko Yagi , Masato Koike ...
来源:[J].Developmental Biology(IF 3.868), 2008, Vol.315 (2), pp.474-488
摘要:Abstract(#br)Src family kinases (SFKs) have been implicated in the regulation of cell motility. To verify their in vivo roles during development, we generated mutant mice in which Csk, a negative regulator of SFKs, was inactivated in neural crest lineages using the Protein zero ...
作者:Pratik Rajeev Chaudhari , Silvania Emlit Charles , Zinia Charlotte D'Souza ...
来源:[J].Experimental Cell Research(IF 3.557), 2017
摘要:Abstract(#br)BPAG1e and Plectin are hemidesmosomal linker proteins which anchor intermediate filament proteins to the cell surface through β4 integrin. Recent reports indicate that these proteins play a role in various cellular processes apart from their known anchoring functi...
作者:Francesca Brescia , Martina Marchetti-Deschmann , Rita Musetti ...
来源:[J].Microbiological Research(IF 1.993), 2020, Vol.234
摘要:... The lower quantity of nutrients available in RMA as compared with LBA was associated to a higher expression of a gene encoding cAMP-receptor-like protein (Clp), responsible for cell motility and biofilm formation regulation. AZ78 cells on RMA were motile, equipped with cell s...
作者:Carla Zimmerman , Pamela Austin , Anthony Khong ...
来源:[J].Experimental Cell Research(IF 3.557), 2013, Vol.319 (6), pp.908-917
摘要:Abstract(#br)Individual tumor cells utilize one of two modes of motility to invade the extracellular matrix, mesenchymal or amoeboid. We have determined that the diterpenoid genkwanine M (GENK) enhances the mesenchymal mode of cell motility that is intrinsic to HT-1080 osteosarco...
作者:Evan Mills , Kevin Truong
来源:[J].Cell Calcium(IF 4.327), 2013, Vol.53 (3), pp.231-240
摘要:Abstract(#br)Several recent reports have demonstrated how engineered proteins can control cell motility, an important functional module for ultimately programming cells as therapeutics. We have reported two engineered proteins that regulate the blebbing cell morphology using chim...
作者:Jian Jing , Elizabeth Tarbutton , Gayle Wilson ...
来源:[J].European Journal of Cell Biology(IF 3.213), 2009, Vol.88 (6), pp.325-341
摘要:Abstract(#br)Cell adhesion and motility are very dynamic processes that require the temporal and spatial coordination of many cellular structures. ADP-ribosylation factor 6 (Arf6) has emerged as master regulator of endocytic membrane traffic and cytoskeletal dynamics during cell ...
作者:Chien-Chang Chen , Patrick Chin-Ho Hsieh , Guo-Ming Wang ...
来源:[J].Materials Letters(IF 2.224), 2009, Vol.63 (21), pp.1872-1875
摘要:Abstract(#br)The purpose of this study is to measure the cell motility under different stiffness and pattern of the substrata. Human melanoma cells were used for this study. Three surface patterns including flat, 6 µm-cone, and 6 µm-groove on polydimethylsiloxane (PDMS) were c...

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