全部文献期刊会议图书|学者科研项目
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作者:Jessica N. Blom , Qingping Feng
来源:[J].Pharmacology and Therapeutics(IF 7.793), 2018, Vol.186, pp.114-129
摘要:... The advancement of treatments to improve cardiac repair post-MI requires the discovery of new targeted treatment strategies. Recent studies have highlighted the importance of the epicardial covering of the heart in both cardiac development and lower vertebrate cardiac regener...
作者:Kazumasa Unno , Angelos Oikonomopoulos , Yusuke Fujikawa ...
来源:[J].Journal of Molecular and Cellular Cardiology(IF 5.148), 2019, Vol.133, pp.174-187
摘要:... While studies suggest that, at best, the adult mammalian heart is capable of very limited regeneration arising from the proliferation of existing cardiomyocytes, how myocardial stress affects endogenous cardiac regeneration or repair is unknown. To define the relationship bet...
作者:Meng-Xin Cai , Xiu-Chao Shi , Ting Chen ...
来源:[J].Life Sciences(IF 2.555), 2016, Vol.149, pp.1-9
摘要:... The Neuregulin 1 (NRG1)/ErbB signaling plays a critical role in cardiac repair and regeneration in the failing heart. We sought to investigate whether ET following MI could activate the NRG1/ErbB signaling and promote cardiac repair and regeneration.(#br)Main methods(#br)Male...
作者:Zefu Yang , Jianping Wan , Wei Pan ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018, Vol.113, pp.179-185
摘要:... In conclusion, the increased vascular endothelial growth factor expression could play an essential role in cardiac repair following the onset of acute myocardial infarction.
作者:Wenjuan Yin , Jian Guo , Chongyu Zhang ...
来源:[J].Journal of Molecular and Cellular Cardiology(IF 5.148), 2019, Vol.132, pp.36-48
摘要:Abstract(#br)Background(#br)Cardiac repair depends on angiogenesis and cell proliferation. Previously we identified Canopy 2 (CNPY2) as a secreted angiogenic growth factor which promotes neovascularization. We investigated the role of CNPY2 in cardiac repair following myocardia...
作者:Kai Zhu , Meiying Wu , Hao Lai ...
来源:[J].Biomaterials(IF 7.604), 2016, Vol.74, pp.188-199
摘要:Abstract(#br)Transplantation of gene-transfected bone marrow-derived mesenchymal stem cells (BMMSCs) is a promising strategy for ischemic myocardium repair, but current therapeutic strategy suffers from high toxicity and inefficient gene transfection in primary BMMSCs. Here ...
作者:Yanqing Gong , Yujing Zhao , Ying Li ...
来源:[J].Journal of the American College of Cardiology(IF 14.086), 2014, Vol.63 (25), pp.2862-2872
摘要:Objectives(#br)The purpose of this study was to investigate the role of plasminogen (Plg) in stem cell–mediated cardiac repair and regeneration after myocardial infarction (MI).(#br)Background(#br)An MI induces irreversible tissue damage, eventually leading to heart failure. ...
作者:Kaveh Moradi , Mehdi Abbasi , Farid Aboulhasani ...
来源:[J].Iranian Journal of Basic Medical Sciences(IF 0.243), 2015, Vol.18 (6), pp.563-570
摘要:... In order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hUCM and VEGF on an infarcted heart. The main objective of this research is to investigate the combinatory effect of dhUCM an...
作者:Y. Wang , P. Lu , D. Zhao ...
来源:[J].Herz(IF 0.779), 2017, Vol.42 (7), pp.662-668
摘要:... Recently, the Hh signal pathway has emerged as an important regulator that can increase cardiomyocyte proliferation, inhibit cardiomyocyte death and apoptosis, recruit endothelial progenitor cell (EPCs) into sites of myocardial ischemia, and direct stem cells to differentiate into cardiac...
作者:Qian Zhang , Weixin Sun , Jie Han ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2020, Vol.523 (4), pp.993-1000
摘要:... In the present study, we examined a circular RNA, hsa_circ_0007623, which is highly expressed in hypoxia-induced human umbilical vein endothelial cells (HUVECs) and can act as a sponge for miR-297, which is involved in cardiac repair after acute myocardial ischemia. In hypoxi...

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