全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Lingling Sun , Rui Dong , Xin Xu ...
来源:[J].Journal of Neuroinflammation(IF 4.351), 2017, Vol.14 (1)Springer
摘要:... Accumulated evidence indicates that cannabinoid receptor type 2 (CB2R) can mediate anti-inflammatory and immunomodulatory effects in part by controlling microglial activity. However, the impact of CB2R on postoperative cognition has not been investigated. We hypothesized that...
作者:Teruyo Hosoya , Dai Fukumoto , Takeharu Kakiuchi ...
来源:[J].Journal of Neuroinflammation(IF 4.351), 2017, Vol.14 (1)Springer
摘要:Upregulated levels of 18-kDa translocator proteins (TSPO) and type 2 endocannabinoid receptors (CB2) are considered to reflect different aspects of microglia-related neuroinflammatory responses in the brain. Relative to the increase in the TSPO expression that occurs slightly lat...
作者:Gabriele Murineddu , Battistina Asproni , Paola Corona ...
来源:[J].Molecules(IF 2.428), 2019, Vol.24 (9)DOAJ
摘要:In this work, the synthesis of the cannabinoid receptor 1 neutral antagonists 8-chloro-1-(2,4-dichlorophenyl)- N -piperidin-1-yl-4,5-dihydrobenzo-1 H -6-oxa-cyclohepta[1,2- c ]pyrazole-3-carboxamide 1a and its deaza N- cyclohexyl analogue 1b has led to a deepening of the str...
作者:Evelyn López-Dyck , Felipa Andrade-Urzúa , Alejandro Elizalde ...
来源:[J].Pharmacological Reports(IF 1.965), 2017Elsevier
摘要:...(#br)Methods(#br)To screen the expression of CB 1 (Cannabinoid receptor 1) and CB 2 (Cannabinoid receptor 2) receptors in arterial rings or isolated smooth muscle cells obtained from the artery, immunocytochemistry, immunohistochemistry, and confocal microscopy were performed....
作者:M. Yu. Bobrov , V. V. Bezuglov , L. G. Khaspekov ...
来源:[J].Bulletin of Experimental Biology and Medicine(IF 0.341), 2017, Vol.163 (2), pp.272-275Springer
摘要:Differential expression of type 1 cannabinoid receptors (CR1) was evaluated at different stages of human skin fibroblast transformation into terminally differentiated neurons. Immunocytochemical staining detected no CR1 on fibroblasts, but their transformation into induced plurip...
作者:Arulkumar Nagappan , Jooyeon Shin , Myeong Ho Jung
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2019, Vol.20 (9)DOAJ
摘要:Endogenous cannabinoids (ECs) are lipid-signaling molecules that specifically bind to cannabinoid receptor types 1 and 2 (CB1R and CB2R) and are highly expressed in central and many peripheral tissues under pathological conditions. Activation of hepatic CB1R is associated with ob...
作者:Zhen Xu , Xiao-Ai Lv , Qun Dai ...
来源:[J].Molecular Brain(IF 4.202), 2016, Vol.9 (1)Springer
摘要:... Type-1 cannabinoid receptor (CB1) is a G-protein coupled receptor (GPCR) enriched on neuronal plasma membrane. Recent evidences point to the substantial presence of CB1 receptors on neuronal mitochondrial outer membranes (mtCB1) and the activation of mtCB1 influences aerobic ...
作者:Antonietta Gentile , Diego Fresegna , Alessandra Musella ...
来源:[J].Journal of Neuroinflammation(IF 4.351), 2016, Vol.13 (1)Springer
摘要:... Anatomical, biochemical, and pharmacological evidence indicates that type-1 cannabinoid receptor (CB1R) is implicated in the control of emotional behavior and is modulated during inflammatory neurodegenerative diseases such as MS and experimental autoimmune encephalomyel...
作者:Qi-xin Shi , Liu-kun Yang , Wen-long Shi ...
来源:[J].Molecular Brain(IF 4.202), 2017, Vol.10 (1)Springer
摘要:The G protein-coupled receptor 55 (GPR55) is a novel cannabinoid receptor, whose exact role in anxiety remains unknown. The present study was conducted to explore the possible mechanisms by which GPR55 regulates anxiety and to evaluate the effectiveness of O-1602 in the treatment...
作者:Evelyn López-Dyck , Felipa Andrade-Urzúa , Alejandro Elizalde ...
来源:[J].Pharmacological Reports(IF 1.965), 2017, Vol.69 (vember), pp.1131-1139Springer
摘要:... Methods(#br)To screen the expression of CB1 (Cannabinoid receptor 1) and CB2 (Cannabinoid receptor 2) receptors in arterial rings or isolated smooth muscle cells obtained from the artery, immunocytochemistry, immunohistochemistry, and confocal microscopy...

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