全部文献期刊会议图书|学者科研项目
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作者:Malte Puchert , Fabian Pelkner , Gregor Stein ...
来源:[J].Molecular and Cellular Neuroscience(IF 3.837), 2017, Vol.85, pp.105-118
摘要:Abstract(#br)Based on our previous demonstration of CXCR7 as the major mediator of CXCL12 signaling in cultured astrocytes, we have now compared astrocytic expression of the CXCL12 receptors, CXCR7 and CXCR4, during CNS development and disease. In addition, we asked whether di...
作者:Dominik Rath , Madhumita Chatterjee , Lennart Meyer ...
来源:[J].Atherosclerosis(IF 3.706), 2018
摘要:... SDF-1 ligates to CXCR4 and CXCR7 and contributes to the regulation of platelet survival. Platelet CXCR4/CXCR7 are involved in myocardial regeneration after infarction and are associated with outcomes in patients with symptomatic coronary artery disease. This study investiga...
作者:Zhi-Yu Song , Feng Wang , Shu-Xiang Cui ...
来源:[J].Oncogene(IF 7.357), 2019, Vol.38 (9), pp.1560-1575
摘要:... Compared with adjacent non-neoplastic tissue, human colorectal cancer (CRC) tissue showed a significant higher expression of CXCR4 and CXCR7, which was colocalized in the cancer cell epithelium. The CXCR/CXCR4 heterodimerization was associated with increased histone demethyl...
作者:Y Qiao , C Zhang , A Li ...
来源:[J].Oncogene(IF 7.357), 2018, Vol.37 (7), pp.873-883
摘要:... We found that interleukin 6 (IL6) derived mainly from cancer-associated fibroblasts played the most important role in chemoresistance by upregulating C-X-C motif chemokine receptor 7 (CXCR7) expression through signal transducer and activator of transcription 3/nuclear facto...
作者:A C Stacer , J Fenner , S P Cavnar ...
来源:[J].Oncogene(IF 7.357), 2016, Vol.35 (13), pp.1716-1724
摘要:Abstract(#br)Atypical chemokine receptor CXCR7 (ACKR3) functions as a scavenger receptor for chemokine CXCL12, a molecule that promotes multiple steps in tumor growth and metastasis in breast cancer and multiple other malignancies. Although normal vascular endothelium express...
作者:Delaine K. Ceholski , Irene C. Turnbull , Venu Pothula ...
来源:[J].Stem Cell Research(IF 4.467), 2017, Vol.23, pp.77-86
摘要:Abstract(#br)CXCR4 and CXCR7 are prominent G protein-coupled receptors (GPCRs) for chemokine stromal cell-derived factor-1 (SDF-1/CXCL12). This study demonstrates that CXCR4 and CXCR7 induce differential effects during cardiac lineage differentiation and β-adrenergic response i...
作者:Dong Chen , Yanli Xia , Ke Zuo ...
来源:[J].Scientific Reports(IF 2.927), 2015, Vol.5 (1), pp.505-513
摘要:... CXCR7, a novel receptor for SDF-1, has been identified recently. We aimed to explore the roles of SDF-1/CXCR4 and SDF-1/CXCR7 pathway and their crosstalk in CSCs migration. In the present study, CXCR4 and CXCR7 expression were identified in CSCs. Transwell assay showed that S...
作者:Y-C Wu , S-J Tang , G-H Sun ...
来源:[J].Oncogene(IF 7.357), 2016, Vol.35 (16), pp.2123-2132
摘要:... We found that CXCR7 was the most upregulated chemokine receptor induced by TGFβ1. CXCR7 knockdown resulted in reduction of migration, invasion and EMT induced by TGFβ1, whereas CXCR4 knockdown did not reverse TGFβ1-promoted EMT. CXCR7 silencing significantly decre...
作者:Mingang Hao , Xiaoling Weng , Yingying Wang ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2018, Vol.147, pp.128-140
摘要:Abstract(#br)Chemokine (C-X-C motif) receptor 7 (CXCR7) has been established to be involved in breast cancer (BCa) progression. However, the role of CXCR7 in different subtype of BCa still remains unclear. Here we note that CXCR7 expression is significantly amplified in Luminal ...
作者:Françoise Trousse , Achraf Jemli , Michèle Silhol ...
来源:[J].Brain Behavior and Immunity(IF 5.612), 2019, Vol.80, pp.697-710
摘要:Abstract(#br)In adult brain, the chemokine CXCL12 and its receptors CXCR4 and CXCR7 are expressed in neural progenitor and glial cells. Conditional Cxcl12 or Cxcr4 gene knockout in mice leads to severe alterations in neural progenitor proliferation, migration and differentiatio...

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