全部文献期刊会议图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Robert Plummer , Guo-fu Hu , Tiegang Liu ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2020
摘要:... The expression of cyclo-oxygenase-2 (COX-2) and phosphorylation of PKD was assessed by Western Blot.(#br)Results(#br)Primary mouse and human colonic myofibroblasts exposed to TNF-α/BK led to enhanced PKD phosphorylation and synergistic COX-2 expression. 18Co cells secret...
作者:Hu Yang , Yang Xuefeng , Wu Shandong ...
来源:[J].Clinica Chimica Acta(IF 2.85), 2020
摘要:Abstract(#br)As a vital inducible sensor, cyclooxygenase-2 (COX-2) plays an important role in the progress of hepatic fibrogenesis. Activation of hepatic stellate cells (HSCs) in the liver can significantly accelerate the onset and development of liver fibrosis. COX-2 overexpress...
作者:Asweni Baskaran , Kek Heng Chua , Vikineswary Sabaratnam ...
来源:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
摘要:Pleurotus giganteus (Berk. Karunarathna and K.D. Hyde), has been used as a culinary mushroom and is known to have medicinal properties but its potential as an anti-inflammatory agent to mitigate inflammation triggered diseases is untapped. In this study, the molecular mechanism u...
作者:Ping Zhou , Jiaqi Qin , Yuan Li ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:... Recent studies demonstrate that the melanoma metastasis has correlations with the heightened activations of protein kinase C ζ (PKCζ) and cyclooxygenase-2 (COX-2) signaling pathways. Targeted inhibitions for PKCζ and COX-2 have been considered as the promising strategies ...
作者:Wei Li , Yuanyuan Cao , Jinling Xu ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:... COX-2 (cyclooxygenase 2) is involved in drug resistance and poor prognosis of many neoplastic diseases or cancers. However, investigations identifying new modulators of COX-2 pathway and searching for new chemicals targeting these valid resistant biomarkers are still greatly ...
作者:Gerardo Botti , Federica Fratangelo , Margherita Cerrone ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2017, Vol.15 (1)Springer
摘要:... COX-2 is currently investigated as a major player of tumor progression in several type of malignancies including melanoma. In the present study we investigated the potential relationship between COX-2 and PD-L1 expression in melanoma.
作者:Chi F , Wu R , Jin X ...
来源:[J].OncoTargets and Therapy(IF 2.073), 2016, Vol.2016 (Issue 1), pp.2709-2716DOAJ
摘要:... In this study, quantitative reverse transcription polymerase chain reaction (qRT-PCR) was performed to detect HER2 and COX-2 expression in NSCLC tissues. Then, pcDNA3.1-HER2 was used to overexpress HER2, while HER2 siRNA and COX-2 siRNA were used to silence HER2 and COX-2...
作者:Hui-juan Su , Yang Zhang , Lian Zhang ...
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:... To investigate the association between methylation of COX-2 in blood leukocyte DNA and risk of gastric cancer (GC), a nested case–control study was conducted in Linqu County, Shandong Province, a high risk area of GC in China.(#br) Methods(#br)Association between blood...
作者:Tong F , Dong B , Chai R ...
来源:[J].International Journal of Nanomedicine(IF 3.463), 2017, Vol.Volume 12, pp.2477-2488DOAJ
摘要:Fei Tong,1 Bo Dong,1 Rongkui Chai,1 Ke Tong,2,3 Yini Wang,4 Shipiao Chen,1 Xinmei Zhou,1 Daojun Liu5 1Department of Pathology and Pathophysiology, Provincial Key Discipline of Pharmacology, Jiaxing University Medical College, Jiaxing, Zhejiang, 2College of Life Science and Engineering, 3State Defense Key Laboratory of Fundamental Science on Nuclear Wastes and Environment, Southwest University of Science and Technology, Mianyang, Sichuan, 4Department of Nursing, Zhejiang Rongjun Hospital, The Third People’s Hospital of Jiaxing, Jiaxing, Zhejiang, 5Department of Pharmacochemistry, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China Abstract: The purpose of the research was to explore the therapeutic action of simvastatin-loaded poly(ethylene glycol)-b-poly(gamma-benzyl l-glutamate) (PEG-b-PBLG50) on intestinal ischemia/reperfusion injury (II/RI) through downregulating bone morphogenetic protein 4 (BMP4)/cyclooxygenase-2 (COX-2
作者:Eun-Mi Choi , Sahng-June Kwak , Young-Myeong Kim ...
来源:[J].Experimental & Molecular Medicine, 2005, Vol.37 (3), pp.199-203
摘要:Abstract(#br)Cyclooxygenase-2 (COX-2) has been reported to be associated with tumor development and progression as well as to protect cells from apoptosis induced by various cellular stresses. Through a tetracycline-regulated COX-2 overexpression system, we found that COX-2 inhib...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×